STRINGSTRING
BRAF BRAF SOS2 SOS2 ARAF ARAF IPO7 IPO7 NR4A1 NR4A1 MTOR MTOR LOX LOX FOS FOS SOS1 SOS1 IFNG IFNG ABL1 ABL1 RABIF RABIF KRAS KRAS NRAS NRAS PLK1 PLK1 NLK NLK BRD4 BRD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
SOS2Uncharacterized protein. (1332 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
IPO7Importin-7. (1038 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (670 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
LOXLysyl oxidase. (417 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1345 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
RABIFRAB interacting factor. (179 aa)
KRASKRAS proto-oncogene, GTPase. (412 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
BRD4Bromodomain containing 4. (1334 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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