STRINGSTRING
L1CAM L1CAM SCN8A SCN8A PKP2 PKP2 FGF14 FGF14 CD44 CD44 SHANK3 SHANK3 TRANK1 TRANK1 FGF2 FGF2 TNKS2 TNKS2 FGF5 FGF5 SHANK1 SHANK1 FGF7 FGF7 FGF9 FGF9 GABARAP GABARAP FGF16 FGF16 TGFB3 TGFB3 DMD DMD USP9X USP9X FGF8 FGF8 RHBG RHBG SCN3A SCN3A FGF18 FGF18 ZDHHC8 ZDHHC8 SRC SRC PRKACG PRKACG NRCAM NRCAM SEMA6B SEMA6B TGFB1 TGFB1 FGF21 FGF21 ZDHHC5 ZDHHC5 INS INS NGF NGF HOOK1 HOOK1 FGF13 FGF13 ATP1A1 ATP1A1 GABARAPL1 GABARAPL1 SCN1A SCN1A FGF10 FGF10 PRKACA PRKACA TIAM1 TIAM1 PRKACB PRKACB FADD FADD SCN1B SCN1B SCHIP1 SCHIP1 NFASC NFASC SYK SYK TGFB2 TGFB2 EMX1 EMX1 CREBBP CREBBP ANKRD16 ANKRD16 PVALB PVALB FGF6 FGF6 FGF1 FGF1 NDEL1 NDEL1 FGF22 FGF22 FGF12 FGF12 EFNB1 EFNB1 RABIF RABIF FGF11 FGF11 FGF4 FGF4 FGF3 FGF3 FYN FYN FGF20 FGF20 FGF19 FGF19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L1CAMUncharacterized protein. (1420 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
PKP2Plakophilin 2. (790 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
CD44Phagocytic glycoprotein I. (742 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1730 aa)
TRANK1Tetratricopeptide repeat and ankyrin repeat containing 1. (3088 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
TNKS2Poly [ADP-ribose] polymerase. (1258 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2163 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
DMDUncharacterized protein. (3685 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2559 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RHBGAmmonium transporter Rh type B; Functions as a specific ammonium transporter; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (458 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (778 aa)
SRCTyrosine-protein kinase. (644 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
NRCAMNeuronal cell adhesion molecule. (1308 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (948 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (672 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (294 aa)
HOOK1Hook microtubule tethering protein 1. (728 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
GABARAPL1Uncharacterized protein. (146 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
TIAM1Uncharacterized protein. (1591 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
SCHIP1Uncharacterized protein. (565 aa)
NFASCNeurofascin. (1464 aa)
SYKTyrosine-protein kinase. (635 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EMX1Homeobox protein EMX1. (290 aa)
CREBBPCREB-binding protein isoform a. (2442 aa)
ANKRD16Ankyrin repeat domain 16. (361 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (178 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (380 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
EFNB1EPH-related receptor tyrosine kinase ligand 2; Belongs to the ephrin family. (346 aa)
RABIFRAB interacting factor. (179 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
FYNTyrosine-protein kinase. (589 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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