12 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1730 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (194 aa)
	CALM2	Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
	BDNF	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
	CALML3	Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
	CALML6	Calmodulin like 6. (181 aa)
	LOC717686	Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
	CALML5	Calmodulin-like protein 5. (146 aa)
	CNTNAP2	Contactin associated protein like 2. (1331 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2163 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	CALM2	ENSMMUP00000059263	ENSMMUP00000076065	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Uncharacterized protein; Belongs to the calmodulin family.	0.623
BDNF	CALM3	ENSMMUP00000059263	ENSMMUP00000076991	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin 3; Belongs to the calmodulin family.	0.623
BDNF	CALML3	ENSMMUP00000059263	ENSMMUP00000053471	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	0.622
BDNF	CALML5	ENSMMUP00000059263	ENSMMUP00000022969	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin-like protein 5.	0.623
BDNF	CALML6	ENSMMUP00000059263	ENSMMUP00000045683	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin like 6.	0.632
BDNF	LOC717686	ENSMMUP00000059263	ENSMMUP00000045604	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Uncharacterized protein; Belongs to the calmodulin family.	0.623
BDNF	MECP2	ENSMMUP00000059263	ENSMMUP00000055953	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.910
CALM2	BDNF	ENSMMUP00000076065	ENSMMUP00000059263	Uncharacterized protein; Belongs to the calmodulin family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.623
CALM2	CALM3	ENSMMUP00000076065	ENSMMUP00000076991	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin 3; Belongs to the calmodulin family.	0.904
CALM2	CALML3	ENSMMUP00000076065	ENSMMUP00000053471	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	0.902
CALM2	CALML5	ENSMMUP00000076065	ENSMMUP00000022969	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin-like protein 5.	0.908
CALM2	CALML6	ENSMMUP00000076065	ENSMMUP00000045683	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin like 6.	0.904
CALM3	BDNF	ENSMMUP00000076991	ENSMMUP00000059263	Calmodulin 3; Belongs to the calmodulin family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.623
CALM3	CALM2	ENSMMUP00000076991	ENSMMUP00000076065	Calmodulin 3; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.904
CALM3	CALML3	ENSMMUP00000076991	ENSMMUP00000053471	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	0.901
CALM3	CALML5	ENSMMUP00000076991	ENSMMUP00000022969	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin-like protein 5.	0.904
CALM3	CALML6	ENSMMUP00000076991	ENSMMUP00000045683	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin like 6.	0.917
CALML3	BDNF	ENSMMUP00000053471	ENSMMUP00000059263	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.622
CALML3	CALM2	ENSMMUP00000053471	ENSMMUP00000076065	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.902
CALML3	CALM3	ENSMMUP00000053471	ENSMMUP00000076991	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	Calmodulin 3; Belongs to the calmodulin family.	0.901