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ACSL4 ACSL4 SDHB SDHB LAMP2 LAMP2 ATP5F1B ATP5F1B SUCLG1 SUCLG1 ATP5F1D ATP5F1D SOD2 SOD2 VDAC1 VDAC1 MDH2 MDH2 ATP5MG ATP5MG COX4I1 COX4I1 LOC700087 LOC700087 NDUFV2 NDUFV2 GCG GCG COX5B COX5B ATP5PB ATP5PB NDUFB7 NDUFB7 ATP5F1A ATP5F1A SDHD-2 SDHD-2 NDUFA5 NDUFA5 ATP5ME ATP5ME NDUFA10 NDUFA10 PALB2 PALB2 COX7C COX7C SDHA SDHA NDUFS1 NDUFS1 HSD17B10 HSD17B10 SDHC SDHC INS INS IDE IDE LOC716527 LOC716527 UQCRC2 UQCRC2 TCIRG1 TCIRG1 NDUFS8 NDUFS8 NDUFV1 NDUFV1 ASAH1 ASAH1 SDHD SDHD UQCRC1 UQCRC1 FLOT1 FLOT1 CD68 CD68 FLOT2 FLOT2 ATP5PD ATP5PD ETFA ETFA LAMP1 LAMP1 NDUFB5 NDUFB5 ATP5PF ATP5PF NDUFS3 NDUFS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACSL4Long-chain-fatty-acid--CoA ligase 4 isoform 2. (711 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
LAMP2Lysosome-associated membrane glycoprotein 2 isoform B. (410 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
ATP5F1DATP synthase subunit delta, mitochondrial. (168 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (283 aa)
MDH2Malate dehydrogenase. (338 aa)
ATP5MGATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (114 aa)
COX4I1Uncharacterized protein. (169 aa)
LOC700087Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
NDUFV2Uncharacterized protein. (253 aa)
GCGGlucagon. (263 aa)
COX5BCytochrome c oxidase subunit 5B. (182 aa)
ATP5PBUncharacterized protein. (290 aa)
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (137 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (623 aa)
SDHD-2Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (85 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
ATP5MEUncharacterized protein. (221 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (387 aa)
PALB2PALB2_WD40 domain-containing protein. (1205 aa)
COX7CCytochrome c oxidase subunit 7C. (91 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (705 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
HSD17B103-hydroxyacyl-CoA dehydrogenase type-2 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
SDHCUncharacterized protein. (176 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
IDEUncharacterized protein; Belongs to the peptidase M16 family. (1019 aa)
LOC716527Flotillin-2. (428 aa)
UQCRC2Uncharacterized protein; Belongs to the peptidase M16 family. (519 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (853 aa)
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (210 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (467 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (507 aa)
FLOT1Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (439 aa)
CD68CD68 molecule. (354 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
ETFAElectron transfer flavoprotein subunit alpha. (346 aa)
LAMP1Lysosomal associated membrane protein 1. (733 aa)
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 1. (189 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (116 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (264 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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