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CLOCK CLOCK SCN8A SCN8A GABRG2 GABRG2 PDXK PDXK APEH APEH YWHAH YWHAH SCN1A SCN1A PER3 PER3 MECP2 MECP2 KCNJ10 KCNJ10 GABRB1 GABRB1 CHRNA2 CHRNA2 DBP DBP KCNA1 KCNA1 SCN1B SCN1B LOC719678 LOC719678 CRY2 CRY2 SLC7A6OS SLC7A6OS GABRA1 GABRA1 GABRB3 GABRB3 CRY1 CRY1 ARX ARX EEF1A2 EEF1A2 TEF TEF CHRNB2 CHRNB2 SLC22A1 SLC22A1 HLF HLF GNAO1 GNAO1 PER2 PER2 STXBP1 STXBP1 KCNQ2 KCNQ2 CHRNA4 CHRNA4 KCNQ5 KCNQ5 GAD1 GAD1 DNM1 DNM1 ABCB1 ABCB1 KCNQ3 KCNQ3 SLC6A1 SLC6A1 SLC6A11 SLC6A11 ALB ALB CACNA1A CACNA1A PNPO PNPO SCN2A SCN2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLOCKClock circadian regulator. (852 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
GABRG2Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
PDXKPyridoxal kinase. (312 aa)
APEHPeptidase_S9 domain-containing protein. (773 aa)
YWHAHDEP domain-containing protein. (1603 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
PER3Period circadian regulator 3. (1178 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (530 aa)
DBPD-box binding PAR bZIP transcription factor. (434 aa)
KCNA1Voltage-gated potassium channel subunit Kv1.1; Belongs to the potassium channel family. (495 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
LOC719678Uncharacterized protein. (626 aa)
CRY2Cryptochrome circadian regulator 2. (593 aa)
SLC7A6OSSolute carrier family 7 member 6 opposite strand. (308 aa)
GABRA1Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3 isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
ARXAristaless related homeobox. (562 aa)
EEF1A2Eukaryotic translation elongation factor 1 alpha 2. (706 aa)
TEFTEF transcription factor, PAR bZIP family member. (303 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
SLC22A1Solute carrier family 22 member 1. (554 aa)
HLFHepatic leukemia factor. (295 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa)
PER2Period circadian regulator 2. (1254 aa)
STXBP1Syntaxin-binding protein 1 isoform a; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2. (1110 aa)
CHRNA4Uncharacterized protein. (625 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)
GAD1Glutamate decarboxylase 1 isoform GAD67. (594 aa)
DNM1Dynamin-1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ABCB1ATP binding cassette subfamily B member 4. (1316 aa)
KCNQ3Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family. (872 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (632 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa)
PNPOPyridoxamine 5'-phosphate oxidase. (261 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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