STRINGSTRING
NEU2 NEU2 DEGS1 DEGS1 SMPD4 SMPD4 ACER1 ACER1 KDSR KDSR ASAH2 ASAH2 SMPD1 SMPD1 PSAP PSAP CERS6 CERS6 ASAH1 ASAH1 ENPP7 ENPP7 CERS3 CERS3 ACER3 ACER3 SMPD3 SMPD3 UGCG UGCG NEU1 NEU1 SGPP1 SGPP1 SPHK2 SPHK2 CERS2 CERS2 GBA2 GBA2 B4GALT6 B4GALT6 SPTLC2 SPTLC2 SPHK1 SPHK1 SGPL1 SGPL1 GLA GLA SPTLC1 SPTLC1 GALC GALC ACER2 ACER2 GLB1 GLB1 CERS1 CERS1 PSAPL1 PSAPL1 GBA GBA DEGS2 DEGS2 CERK CERK GAL3ST1 GAL3ST1 NEU4 NEU4 SGPP2 SGPP2 ARSA ARSA SGMS2 SGMS2 UGT8 UGT8 SMPD2 SMPD2 SPTLC3 SPTLC3 SGMS1 SGMS1 PLPP3 PLPP3 PLPP1 PLPP1 CERS4 CERS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEU2Neuraminidase 2. (381 aa)
DEGS1Sphingolipid delta(4)-desaturase DES1. (323 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (827 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
ASAH2Neutral ceramidase. (780 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (629 aa)
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)
CERS6Uncharacterized protein. (392 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (527 aa)
CERS3Ceramide synthase 3. (385 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
NEU1Neuraminidase 1. (416 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)
SPHK2DAGKc domain-containing protein. (669 aa)
CERS2LAG1 longevity assurance homolog 2. (380 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (927 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (560 aa)
SPHK1Sphingosine kinase 1. (470 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
GLAAlpha-galactosidase. (429 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (473 aa)
GALCGalactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. (685 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
GLB1Beta-galactosidase. (739 aa)
CERS1LAG1 longevity assurance homolog 1 isoform 1. (350 aa)
PSAPL1Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. (521 aa)
GBAGlucosylceramidase. (533 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)
CERKCeramide kinase. (537 aa)
GAL3ST1Galactose-3-O-sulfotransferase 1. (423 aa)
NEU4Neuraminidase 4. (492 aa)
SGPP2acidPPc domain-containing protein. (399 aa)
ARSAArylsulfatase A. (507 aa)
SGMS2Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (548 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (552 aa)
SGMS1Phosphatidylcholine:ceramide cholinephosphotransferase 1. (413 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
PLPP1Lipid phosphate phosphohydrolase 1 isoform 2. (285 aa)
CERS4Ceramide synthase 4. (595 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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