STRINGSTRING
NXF1 NXF1 PPP2R3A PPP2R3A CPSF4L CPSF4L PELO PELO RNMT RNMT MAGOHB MAGOHB PPP2R3B PPP2R3B UPF3A UPF3A TARDBP TARDBP NCBP2 NCBP2 PPP2R5E PPP2R5E EIF4A3 EIF4A3 LOC106995243 LOC106995243 SAP18 SAP18 PABPC1 PABPC1 NXT2 NXT2 PABPC1L PABPC1L PPP2R2C PPP2R2C PPP1CC PPP1CC CPSF7 CPSF7 SYMPK SYMPK PPP1CA PPP1CA CPSF4 CPSF4 FUS FUS PPP2R3C PPP2R3C UPF3B UPF3B DDX19A DDX19A PPP1CB PPP1CB NXF3 NXF3 PPP2CB PPP2CB PABPC3 PABPC3 PPP2R1A PPP2R1A NXT1 NXT1 PPP2R2D PPP2R2D SMG6 SMG6 ETF1 ETF1 PAPOLG PAPOLG SMG7 SMG7 SRRM1 SRRM1 LOC706140 LOC706140 ALYREF ALYREF UPF1 UPF1 PPP2R2A PPP2R2A GLE1 GLE1 CASC3 CASC3 CPSF3 CPSF3 PPP2R1B PPP2R1B DDX39B DDX39B CSTF3 CSTF3 CSTF2 CSTF2 PAPOLA PAPOLA GSPT1 GSPT1 ACIN1 ACIN1 CPSF6 CPSF6 PPP2R5B PPP2R5B NCBP1 NCBP1 NUDT21 NUDT21 MSI2 MSI2 PPP2R5C PPP2R5C PPP2R2B PPP2R2B CSTF1 CSTF1 PPP2R5D PPP2R5D WDR33 WDR33 PABPC4L PABPC4L WDR82 WDR82 PABPC4 PABPC4 SMG1 SMG1 PPP2R5A PPP2R5A RNGTT RNGTT RNPS1 RNPS1 SMG5 SMG5 NCBP2L NCBP2L ENSMMUP00000075823 ENSMMUP00000075823 PYM1 PYM1 SSU72 SSU72 RBM8A RBM8A UPF2 UPF2 CPSF2 CPSF2 CSTF2T CSTF2T PNN PNN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NXF1Nuclear RNA export factor 1 isoform 1. (619 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1120 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (476 aa)
MAGOHBProtein mago nashi homolog 2. (148 aa)
PPP2R3BEF-hand domain-containing protein. (572 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (463 aa)
TARDBPTAR DNA-binding protein 43. (414 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (204 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (471 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
LOC106995243Polyadenylate-binding protein 1-like 2. (200 aa)
SAP18Histone deacetylase complex subunit SAP18. (172 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (638 aa)
NXT2NTF2-related export protein 2 isoform 1. (197 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (629 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (471 aa)
SYMPKSymplekin. (1274 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (224 aa)
FUSTripartite motif containing 72. (534 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (453 aa)
UPF3BUncharacterized protein. (483 aa)
DDX19AUncharacterized protein. (836 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
NXF3Nuclear RNA export factor 3. (543 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (637 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
SMG6Telomerase-binding protein EST1A isoform 1. (1419 aa)
ETF1Eukaryotic peptide chain release factor subunit 1. (437 aa)
PAPOLGPoly(A) polymerase gamma. (747 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1447 aa)
SRRM1Serine and arginine repetitive matrix 1. (906 aa)
LOC706140Tap-RNA_bind domain-containing protein. (356 aa)
ALYREFRRM domain-containing protein. (290 aa)
UPF1UPF1 RNA helicase and ATPase. (1129 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (459 aa)
GLE1Nucleoporin GLE1 isoform 1. (698 aa)
CASC3Btz domain-containing protein. (706 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (684 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (716 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
CSTF3Cleavage stimulation factor subunit 3 isoform 1. (717 aa)
CSTF2Cleavage stimulation factor subunit 2. (626 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
GSPT1G1 to S phase transition 1. (640 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1340 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (588 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (505 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
MSI2Musashi RNA binding protein 2. (340 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
WDR33WD repeat domain 33. (1387 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
WDR82WD repeat-containing protein 82. (313 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3660 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
RNPS1RNA-binding protein with serine-rich domain 1. (305 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1016 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
ENSMMUP00000075823Uncharacterized protein. (290 aa)
PYM1Mago-bind domain-containing protein. (295 aa)
SSU72SSU72 homolog, RNA polymerase II CTD phosphatase. (260 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1299 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
CSTF2TCleavage stimulation factor subunit 2 tau variant. (620 aa)
PNNPinin. (719 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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