STRINGSTRING
SNRPD3 SNRPD3 TXNL4A TXNL4A HNRNPA3 HNRNPA3 RBM25 RBM25 U2SURP U2SURP RP9 RP9 SYF2 SYF2 THOC2 THOC2 PQBP1 PQBP1 TRA2A TRA2A THOC1 THOC1 SRSF1 SRSF1 U2AF2 U2AF2 MAGOHB MAGOHB SF3A1 SF3A1 PRPF4 PRPF4 SNRPD2 SNRPD2 SF3B4 SF3B4 SRSF8 SRSF8 SMNDC1 SMNDC1 NCBP2 NCBP2 DDX5 DDX5 EIF4A3 EIF4A3 DHX15 DHX15 SNRPB SNRPB PRPF38B PRPF38B SNRNP27 SNRNP27 SRSF7 SRSF7 ISY1 ISY1 SF3B2 SF3B2 HNRNPA1 HNRNPA1 EFTUD2 EFTUD2 PPIH PPIH PRPF38A PRPF38A CDC5L CDC5L BCAS2 BCAS2 RBM17 RBM17 PRPF6 PRPF6 SRSF9 SRSF9 SF3B3 SF3B3 USP39 USP39 HNRNPM HNRNPM PPIE PPIE WBP11 WBP11 SNRNP40 SNRNP40 FUS FUS DHX16 DHX16 RBM22 RBM22 SRSF5 SRSF5 SRSF2 SRSF2 SF3B1 SF3B1 SLU7 SLU7 SNRNP200 SNRNP200 SNRNP70 SNRNP70 PUF60 PUF60 F6XM83_MACMU F6XM83_MACMU SNRPC SNRPC HSPA1L HSPA1L DDX46 DDX46 U2AF1 U2AF1 PRPF18 PRPF18 HNRNPU HNRNPU CTNNBL1 CTNNBL1 SRSF6 SRSF6 TRA2B TRA2B LOC708923 LOC708923 LOC106995413 LOC106995413 ALYREF ALYREF LSM2 LSM2 SNRPA SNRPA TCERG1 TCERG1 PCBP1 PCBP1 THOC3 THOC3 LSM7 LSM7 DHX8 DHX8 DDX39B DDX39B SNW1 SNW1 SRSF10 SRSF10 DDX42 DDX42 DDX23 DDX23 ACIN1 ACIN1 NCBP1 NCBP1 SNU13 SNU13 PLRG1 PLRG1 HSPA8 HSPA8 SRSF4 SRSF4 PRPF40B PRPF40B CDC40 CDC40 SF3B6 SF3B6 CWC15 CWC15 RBMXL2 RBMXL2 RBMXL1 RBMXL1 NAA38-2 NAA38-2 PRPF31 PRPF31 LSM6 LSM6 SART1 SART1 LOC106995411 LOC106995411 SNRPD1 SNRPD1 LSM5 LSM5 XAB2 XAB2 PRPF8 PRPF8 PRPF40A PRPF40A SNRPG SNRPG PHF5A PHF5A SF3A3 SF3A3 RBMX RBMX BUD31 BUD31 HSPA1A HSPA1A CCDC12 CCDC12 AQR AQR SRSF3 SRSF3 PPIL1 PPIL1 SNRPB2 SNRPB2 LOC106995447 LOC106995447 NCBP2L NCBP2L ZMAT2 ZMAT2 SF3A2 SF3A2 DHX38 DHX38 RBM8A RBM8A HNRNPC-2 HNRNPC-2 CHERP CHERP HNRNPK HNRNPK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD3Small nuclear ribonucleoprotein D3 polypeptide. (259 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
HNRNPA3Uncharacterized protein. (378 aa)
RBM25RNA binding motif protein 25. (843 aa)
U2SURPU2 snRNP associated SURP domain containing. (1045 aa)
RP9Uncharacterized protein. (221 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
THOC2THO complex subunit 2. (1593 aa)
PQBP1Polyglutamine binding protein 1. (286 aa)
TRA2ATransformer-2 protein homolog alpha. (282 aa)
THOC1THO complex subunit 1. (657 aa)
SRSF1Uncharacterized protein. (287 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (471 aa)
MAGOHBProtein mago nashi homolog 2. (148 aa)
SF3A1Splicing factor 3A subunit 1 isoform 1. (793 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4. (521 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
SF3B4Splicing factor 3B subunit 4. (424 aa)
SRSF8Serine/arginine-rich splicing factor 8. (287 aa)
SMNDC1Survival of motor neuron-related-splicing factor 30. (238 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (204 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
DHX15Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (795 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
PRPF38BPre-mRNA processing factor 38B. (546 aa)
SNRNP27U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (155 aa)
SRSF7Serine and arginine rich splicing factor 7. (329 aa)
ISY1Uncharacterized protein. (408 aa)
SF3B2Splicing factor 3B subunit 2. (895 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1 isoform b. (372 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component isoform a. (972 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
PRPF38APre-mRNA-splicing factor 38A. (312 aa)
CDC5LCell division cycle 5-like protein. (802 aa)
BCAS2Pre-mRNA-splicing factor SPF27. (225 aa)
RBM1745 kDa-splicing factor. (401 aa)
PRPF6Pre-mRNA processing factor 6. (920 aa)
SRSF9Serine/arginine-rich splicing factor 9. (221 aa)
SF3B3Spliceosome-associated protein 130. (1217 aa)
USP39Ubiquitin specific peptidase 39. (732 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
PPIEPeptidylprolyl isomerase E. (369 aa)
WBP11WW domain-binding protein 11. (641 aa)
SNRNP40WD_REPEATS_REGION domain-containing protein. (358 aa)
FUSTripartite motif containing 72. (534 aa)
DHX16Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform 1. (1044 aa)
RBM22Pre-mRNA-splicing factor RBM22. (420 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
SRSF2Serine/arginine-rich splicing factor 2. (221 aa)
SF3B1SF3b1 domain-containing protein. (1310 aa)
SLU7Pre-mRNA-splicing factor SLU7. (586 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2136 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (428 aa)
PUF60Poly(U) binding splicing factor 60. (586 aa)
F6XM83_MACMURRM domain-containing protein. (176 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (159 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
DDX46Putative ATP-dependent RNA helicase DDX46. (1032 aa)
U2AF1Uncharacterized protein. (240 aa)
PRPF18SFM domain-containing protein. (352 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
CTNNBL1DUF1716 domain-containing protein. (579 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
TRA2BTransformer 2 beta homolog. (331 aa)
LOC708923Uncharacterized protein. (320 aa)
LOC106995413Truncated RNA binding motif protein Y-linked. (231 aa)
ALYREFRRM domain-containing protein. (290 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
TCERG1Transcription elongation regulator 1. (1115 aa)
PCBP1Poly(rC)-binding protein 1. (356 aa)
THOC3THO complex subunit 3. (351 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (107 aa)
DHX8DEAH-box helicase 8. (1222 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
SNW1SNW domain-containing protein 1. (536 aa)
SRSF10RRM domain-containing protein. (261 aa)
DDX42ATP-dependent RNA helicase DDX42. (937 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (820 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1340 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
PLRG1Pleiotropic regulator 1 isoform 1. (514 aa)
HSPA8Heat shock cognate 71 kDa protein isoform 1; Belongs to the heat shock protein 70 family. (646 aa)
SRSF4Serine/arginine-rich splicing factor 4. (497 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (892 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
SF3B6Pre-mRNA branch site protein p14. (125 aa)
CWC15Protein CWC15 homolog. (229 aa)
RBMXL2RBMX like 2. (394 aa)
RBMXL1RBMX like 1. (391 aa)
NAA38-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF31Pre-mRNA processing factor 31. (525 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6. (80 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
LOC106995411RRM domain-containing protein. (380 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (152 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (102 aa)
XAB2Pre-mRNA-splicing factor SYF1. (855 aa)
PRPF8Pre-mRNA processing factor 8. (2339 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (957 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (79 aa)
PHF5APHD finger-like domain-containing protein 5A. (110 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
RBMXHeterogeneous nuclear ribonucleoprotein G isoform 1. (391 aa)
BUD31Protein BUD31 homolog. (144 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (642 aa)
CCDC12Coiled-coil domain containing 12. (323 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
SRSF3RRM domain-containing protein. (128 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
LOC106995447RRM domain-containing protein. (629 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
ZMAT2Zinc finger matrin-type 2. (305 aa)
SF3A2Splicing factor 3a subunit 2. (482 aa)
DHX38Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1227 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
HNRNPC-2RRM domain-containing protein. (299 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (927 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K isoform a. (464 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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