STRINGSTRING
RPA3 RPA3 RFC3 RFC3 RFC4 RFC4 RFC2 RFC2 RFC5 RFC5 RPA2 RPA2 POLD3 POLD3 MLH1 MLH1 MSH6 MSH6 PMS2 PMS2 MSH2 MSH2 EXO1 EXO1 RPA1 RPA1 MSH3 MSH3 RFC1 RFC1 PCNA PCNA MLH3 MLH3 LIG1 LIG1 SSBP1 SSBP1 POLD2 POLD2 POLD4 POLD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA3Replication protein A 14 kDa subunit. (121 aa)
RFC3Replication factor C subunit 3 isoform 1. (356 aa)
RFC4Replication factor C subunit 4. (363 aa)
RFC2Replication factor C subunit 2. (233 aa)
RFC5Replication factor C subunit 5 isoform 1. (340 aa)
RPA2Uncharacterized protein. (270 aa)
POLD3DNA polymerase delta subunit 3. (466 aa)
MLH1MutL homolog 1. (756 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (938 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa)
EXO1Exonuclease 1. (846 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1124 aa)
RFC1Replication factor C subunit 1. (1146 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MLH3Uncharacterized protein. (1505 aa)
LIG1DNA ligase. (1108 aa)
SSBP1Uncharacterized protein. (163 aa)
POLD2DNA polymerase delta 2, accessory subunit. (536 aa)
POLD4DNA polymerase delta subunit p12. (107 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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