STRINGSTRING
ANGPT4 ANGPT4 LPAR2 LPAR2 FARP2 FARP2 PLCE1 PLCE1 KRAS KRAS IGF1 IGF1 RASSF5 RASSF5 CSF1 CSF1 DOCK4 DOCK4 PIK3R2 PIK3R2 ITGB3 ITGB3 SIPA1L3 SIPA1L3 VEGFC VEGFC PLCB1 PLCB1 ID1 ID1 VEGFA VEGFA FGFR4 FGFR4 PDGFA PDGFA PIK3CA PIK3CA PDGFD PDGFD GNAI3 GNAI3 THBS1 THBS1 TEK TEK FNIP1 FNIP1 MET MET LPAR1 LPAR1 FGF2 FGF2 MRAS MRAS MAPK14 MAPK14 PIK3CB PIK3CB FGF5 FGF5 PFN4 PFN4 LOC705671 LOC705671 FGF7 FGF7 FGF9 FGF9 EGF EGF ANGPT2 ANGPT2 LOC694289 LOC694289 RAC3 RAC3 PIK3R1 PIK3R1 PDGFRB PDGFRB FGF16 FGF16 CDH1 CDH1 IGF1R IGF1R MAPK1 MAPK1 ITGA2B ITGA2B KDR KDR VEGFB VEGFB PLCB3 PLCB3 FPR1 FPR1 PARD6G PARD6G MAPK11 MAPK11 DRD2 DRD2 NGFR NGFR LOC710997 LOC710997 FIP1L1 FIP1L1 VEGFD VEGFD FGF8 FGF8 MAP2K1 MAP2K1 VAV2 VAV2 CALML5 CALML5 MAGI1 MAGI1 ANGPT1 ANGPT1 ITGB1 ITGB1 MAGI3 MAGI3 PRKD2 PRKD2 EFNA5 EFNA5 HGF HGF FLT4 FLT4 PRKCZ PRKCZ GRIN2B GRIN2B FGF18 FGF18 GNAO1 GNAO1 FGFR3 FGFR3 AKT3 AKT3 GNAI2 GNAI2 SRC SRC ADCY4 ADCY4 AFDN AFDN RAC1 RAC1 FYB1 FYB1 FLT1 FLT1 HRAS HRAS PRKD1 PRKD1 GNAI1 GNAI1 PRKCG PRKCG RRAS RRAS FGF21 FGF21 ITGAL ITGAL RGS14 RGS14 MAP2K3 MAP2K3 RAPGEF5 RAPGEF5 PARD3 PARD3 RALB RALB F6SS94_MACMU F6SS94_MACMU LOC106995524 LOC106995524 CTNND1 CTNND1 INS INS P2RY1 P2RY1 GRIN1 GRIN1 CDC42 CDC42 KRIT1 KRIT1 CRK CRK ACTG1 ACTG1 RAPGEF2 RAPGEF2 ADCY8 ADCY8 BRAF BRAF CALML6 CALML6 PFN3 PFN3 RHOA RHOA EGFR EGFR NGF NGF GRIN2A GRIN2A SIPA1L1 SIPA1L1 FGFR2 FGFR2 ARAP3 ARAP3 ADCY3 ADCY3 TLN2 TLN2 NRAS NRAS MAGI2 MAGI2 ITGAM ITGAM ADCY5 ADCY5 RAP1B RAP1B SIPA1 SIPA1 MAPK3 MAPK3 CSF1R CSF1R CALML3 CALML3 FGF10 FGF10 RAPGEF4 RAPGEF4 F2R F2R RAC2 RAC2 RAPGEF3 RAPGEF3 PLCG1 PLCG1 RAF1 RAF1 RASGRP3 RASGRP3 LCP2 LCP2 TIAM1 TIAM1 LOC710293 LOC710293 TLN1 TLN1 VAV1 VAV1 AKT2 AKT2 MAP2K6 MAP2K6 ADCY2 ADCY2 PIK3R3 PIK3R3 KIT KIT AKT1 AKT1 ADORA2B ADORA2B GNAQ GNAQ PRKCB PRKCB PLCB4 PLCB4 CTNNB1 CTNNB1 EFNA3 EFNA3 ADCY6 ADCY6 RASGRP2 RASGRP2 PDGFB PDGFB FGF23 FGF23 BCAR1 BCAR1 PFN2 PFN2 RALA RALA PIK3CD PIK3CD PLCB2 PLCB2 FGF6 FGF6 LOC710149 LOC710149 RAP1GAP RAP1GAP PARD6B PARD6B ADCY9 ADCY9 PRKCI PRKCI MAP2K2 MAP2K2 ADCY1 ADCY1 CNR1 CNR1 APBB1IP APBB1IP PRKCA PRKCA RAP1A RAP1A FGF1 FGF1 F2RL3 F2RL3 RAPGEF1 RAPGEF1 ENAH ENAH VAV3 VAV3 ITGB2 ITGB2 FGF22 FGF22 LPAR3 LPAR3 ADCY7 ADCY7 LPAR5 LPAR5 PDGFC PDGFC EFNA2 EFNA2 PARD6A PARD6A CALM2 CALM2 SIPA1L2 SIPA1L2 PFN1 PFN1 ENSMMUP00000076578 ENSMMUP00000076578 SKAP1 SKAP1 CALM3 CALM3 EFNA1 EFNA1 LPAR4 LPAR4 KITLG KITLG FGF4 FGF4 EPHA2 EPHA2 FGF3 FGF3 PRKD3 PRKD3 FGF20 FGF20 FGF19 FGF19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANGPT4Angiopoietin 4. (503 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1055 aa)
PLCE1Phosphoinositide phospholipase C. (2317 aa)
KRASKRAS proto-oncogene, GTPase. (412 aa)
IGF1Insulin like growth factor 1. (208 aa)
RASSF5Ras association domain family member 5. (418 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1981 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1777 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ID1DNA-binding protein inhibitor ID-1 isoform a. (154 aa)
VEGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (489 aa)
FGFR4Fibroblast growth factor receptor. (859 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PDGFDPlatelet-derived growth factor D isoform 1. (370 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
THBS1Thrombospondin 1. (1170 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
FNIP1Uncharacterized protein. (1651 aa)
METUncharacterized protein. (1381 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
MRASUncharacterized protein. (214 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
LOC705671Uncharacterized protein. (398 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
ANGPT2Angiopoietin 2. (496 aa)
LOC694289Uncharacterized protein. (394 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
FPR1fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity). (352 aa)
PARD6GPar-6 family cell polarity regulator gamma. (376 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
NGFRNerve growth factor receptor. (427 aa)
LOC710997Ras-GEF domain-containing protein. (490 aa)
FIP1L1Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform 1. (878 aa)
CALML5Calmodulin-like protein 5. (146 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1470 aa)
ANGPT1Angiopoietin-1 isoform 1. (498 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1482 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
EFNA5EPH-related receptor tyrosine kinase ligand 7; Belongs to the ephrin family. (228 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
SRCTyrosine-protein kinase. (644 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
AFDNAfadin, adherens junction formation factor. (1892 aa)
RAC1Uncharacterized protein. (212 aa)
FYB1FYN binding protein 1. (839 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1474 aa)
HRASTransforming protein p21. (189 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
RRASRas-related protein R-Ras. (218 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1169 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
MAP2K3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (467 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (883 aa)
PARD3Partitioning defective 3 homolog isoform 2. (1353 aa)
RALBUncharacterized protein. (286 aa)
F6SS94_MACMURas-GEF domain-containing protein. (447 aa)
LOC106995524Ras-GEF domain-containing protein. (553 aa)
CTNND1Uncharacterized protein. (968 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
CDC42Cell division control protein 42 homolog isoform 1. (191 aa)
KRIT1Krev interaction trapped protein 1 isoform 1. (736 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
CALML6Calmodulin like 6. (181 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
RHOARas homolog family member A. (209 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (294 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SIPA1L1Signal-induced proliferation-associated 1-like protein 1. (1804 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1546 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
TLN2Talin 2. (2547 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1271 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
RAP1BRas-related protein Rap-1b isoform 1. (184 aa)
SIPA1Signal-induced proliferation-associated protein 1. (1042 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1045 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1047 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
RAF1Uncharacterized protein. (668 aa)
RASGRP3Uncharacterized protein. (695 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
TIAM1Uncharacterized protein. (1591 aa)
LOC710293Ras-GEF domain-containing protein. (553 aa)
TLN1Talin 1. (2558 aa)
VAV1Vav guanine nucleotide exchange factor 1. (928 aa)
AKT2AKT serine/threonine kinase 2. (594 aa)
MAP2K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PIK3R3Uncharacterized protein. (507 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
CTNNB1Catenin beta-1. (781 aa)
EFNA3Ephrin-A3; Belongs to the ephrin family. (238 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
RASGRP2RAS guanyl-releasing protein 2. (609 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (935 aa)
PFN2Profilin; Belongs to the profilin family. (412 aa)
RALARas-related protein Ral-A. (206 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC710149Ig-like domain-containing protein. (228 aa)
RAP1GAPRAP1 GTPase activating protein. (853 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP (By similarity). In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. In [...] (472 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (674 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1297 aa)
ENAHENAH actin regulator. (805 aa)
VAV3Vav guanine nucleotide exchange factor 3. (1128 aa)
ITGB2Integrin beta. (911 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (524 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (213 aa)
PARD6APar-6 family cell polarity regulator alpha. (465 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
SIPA1L2Signal induced proliferation associated 1 like 2. (1761 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
ENSMMUP00000076578Ig-like domain-containing protein. (275 aa)
SKAP1Src kinase associated phosphoprotein 1. (457 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
LPAR4Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (283 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
EPHA2EPH receptor A2. (1033 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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