STRINGSTRING
AVPR1A AVPR1A RYR2 RYR2 PDE1A PDE1A PLCE1 PLCE1 ERBB4 ERBB4 TACR1 TACR1 ADRB2 ADRB2 CAMK2B CAMK2B DRD5 DRD5 RYR1 RYR1 GNA11 GNA11 CACNA1A CACNA1A STIM1 STIM1 PLCB1 PLCB1 TPCN1 TPCN1 PDGFA PDGFA DRD1 DRD1 PLCG2 PLCG2 PDGFD PDGFD MCOLN3 MCOLN3 PTGER1 PTGER1 GRIN2D GRIN2D ITPKA ITPKA P2RX1 P2RX1 ATP2A3 ATP2A3 CACNA1F CACNA1F TRHR TRHR CACNA1B CACNA1B EGF EGF LTB4R2 LTB4R2 GRM5 GRM5 LOC694289 LOC694289 LHCGR LHCGR ATP2B3 ATP2B3 PDGFRB PDGFRB HTR2B HTR2B CAMK1D CAMK1D PLCB3 PLCB3 CACNA1C CACNA1C ENSMMUP00000017083 ENSMMUP00000017083 CYSLTR1 CYSLTR1 PLCD3 PLCD3 NOS1 NOS1 CHRM5 CHRM5 PPP3CC PPP3CC CACNA1E CACNA1E MYLK MYLK CD38 CD38 TACR2 TACR2 FIP1L1 FIP1L1 PPP3CB PPP3CB NTSR1 NTSR1 GNA14 GNA14 CHRM1 CHRM1 PTGER3 PTGER3 CACNA1S CACNA1S CALML5 CALML5 ITPKC ITPKC PTK2B PTK2B ATP2B2 ATP2B2 PRKACG PRKACG MCU MCU NOS3 NOS3 ADCY4 ADCY4 PHKG2 PHKG2 CAMK2G CAMK2G CHRM3 CHRM3 PLCZ1 PLCZ1 CHRNA7 CHRNA7 ATP2B1 ATP2B1 P2RX5 P2RX5 GRPR GRPR PRKCG PRKCG SPHK2 SPHK2 ADRB3 ADRB3 EDNRA EDNRA CACNA1G CACNA1G STIM2 STIM2 HTR2A HTR2A CCKBR CCKBR CACNA1I CACNA1I P2RX7 P2RX7 ITPR2 ITPR2 GRIN1 GRIN1 PHKA2 PHKA2 VDAC3 VDAC3 ITPR3 ITPR3 ATP2A2 ATP2A2 ADCY8 ADCY8 SPHK1 SPHK1 PDE1B PDE1B CALML6 CALML6 EGFR EGFR GRIN2A GRIN2A HRH2 HRH2 ITPR1 ITPR1 ADRB1 ADRB1 ADCY3 ADCY3 ORAI1 ORAI1 ASPH ASPH ERBB3 ERBB3 CACNA1D CACNA1D BDKRB2 BDKRB2 EDNRB EDNRB SLC8A2 SLC8A2 CALML3 CALML3 PRKACA PRKACA ADRA1A ADRA1A F2R F2R RYR3 RYR3 CACNA1H CACNA1H PLCG1 PLCG1 AGTR1 AGTR1 P2RX4 P2RX4 CAMK1G CAMK1G ADCY2 ADCY2 PRKACB PRKACB PHKA1 PHKA1 PPP3R1 PPP3R1 HTR7 HTR7 PTAFR PTAFR ADORA2B ADORA2B GNAQ GNAQ PRKCB PRKCB MYLK2 MYLK2 PPIF PPIF P2RX3 P2RX3 PLCB4 PLCB4 AVPR1B AVPR1B CAMK4 CAMK4 PHKB PHKB SLC25A6 SLC25A6 PLCD1 PLCD1 CASQ1 CASQ1 GNA15 GNA15 HTR6 HTR6 ADRA1D ADRA1D ERBB2 ERBB2 CASQ2 CASQ2 OXTR OXTR ORAI3 ORAI3 CXCR4 CXCR4 CHRM2 CHRM2 MYLK4 MYLK4 HTR2C HTR2C HRH1 HRH1 PDGFB PDGFB CAMK1 CAMK1 CYSLTR2 CYSLTR2 SLC25A31 SLC25A31 LOC106999628 LOC106999628 SLC8A3 SLC8A3 HTR5A HTR5A SH2B1 SH2B1 PTGFR PTGFR PLCB2 PLCB2 LOC710149 LOC710149 ADCY9 ADCY9 CAMK2A CAMK2A ADCY1 ADCY1 PRKCA PRKCA ITPKB ITPKB GRIN2C GRIN2C TPCN2 TPCN2 GNAL GNAL ORAI2 ORAI2 ADCY7 ADCY7 PDGFC PDGFC MCOLN2 MCOLN2 CALM2 CALM2 TNNC1 TNNC1 VDAC2 VDAC2 TBXA2R TBXA2R ENSMMUP00000076578 ENSMMUP00000076578 PDE1C PDE1C CCKAR CCKAR CALM3 CALM3 VDAC1 VDAC1 ATP2B4 ATP2B4 HRC HRC TACR3 TACR3 NOS2 NOS2 ADRA1B ADRA1B GRM1 GRM1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
RYR2Ryanodine receptor 2. (4967 aa)
PDE1APhosphodiesterase. (570 aa)
PLCE1Phosphoinositide phospholipase C. (2317 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (415 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (668 aa)
DRD5D(1B) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (478 aa)
RYR1Ryanodine receptor 1. (4928 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa)
STIM1Stromal interaction molecule 1. (684 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
TPCN1Two pore segment channel 1. (888 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa)
DRD1D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. (446 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PDGFDPlatelet-derived growth factor D isoform 1. (370 aa)
MCOLN3Mucolipin 3. (553 aa)
PTGER1Prostaglandin E receptor 1. (581 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1092 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1970 aa)
TRHRThyrotropin-releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (398 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2338 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
LTB4R2Leukotriene B4 receptor 2. (389 aa)
GRM5Metabotropic glutamate receptor 5 isoform a. (1212 aa)
LOC694289Uncharacterized protein. (394 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (704 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D isoform 2; Belongs to the protein kinase superfamily. (385 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
ENSMMUP00000017083Ig-like domain-containing protein. (183 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
CHRM5Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. (532 aa)
PPP3CCSerine/threonine-protein phosphatase. (511 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2412 aa)
MYLKMyosin light chain kinase. (1914 aa)
CD38ADP-ribosyl cyclase 1. (301 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
FIP1L1Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
NTSR1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
GNA14G protein subunit alpha 14. (355 aa)
CHRM1Muscarinic acetylcholine receptor M1; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. (460 aa)
PTGER3Prostaglandin E receptor 3. (460 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CALML5Calmodulin-like protein 5. (146 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
MCUMitochondrial calcium uniporter. (351 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, testis/liver isoform isoform 1; Belongs to the protein kinase superfamily. (406 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (735 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
PLCZ1Phosphoinositide phospholipase C. (608 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
GRPRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (384 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
SPHK2DAGKc domain-containing protein. (669 aa)
ADRB3Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (418 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
STIM2Stromal interaction molecule 2. (840 aa)
HTR2A5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (471 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (450 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2111 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (573 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa)
VDAC3Uncharacterized protein. (299 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1011 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
SPHK1Sphingosine kinase 1. (470 aa)
PDE1BPhosphodiesterase. (538 aa)
CALML6Calmodulin like 6. (181 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
ADRB1Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (478 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (301 aa)
ASPHAspartate beta-hydroxylase. (756 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3 isoform 1. (1342 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
ADRA1AAdrenoceptor alpha 1A. (445 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RYR3Ryanodine receptor 3. (4870 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2352 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (467 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1223 aa)
PPP3R1Uncharacterized protein. (171 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (445 aa)
PTAFRPlatelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. (342 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MYLK2Myosin light chain kinase 2. (603 aa)
PPIFPeptidylprolyl isomerase F. (309 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (468 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (473 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1093 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (399 aa)
PLCD1Phosphoinositide phospholipase C. (777 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
GNA15Uncharacterized protein. (414 aa)
HTR6G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (440 aa)
ADRA1DAdrenoceptor alpha 1D. (570 aa)
ERBB2Receptor protein-tyrosine kinase. (1437 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (446 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
ORAI3Protein orai-3. (295 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (382 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (492 aa)
MYLK4Myosin light chain kinase family member 4. (541 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (489 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa)
CAMK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (494 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (332 aa)
SLC25A31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
LOC106999628Ig-like domain-containing protein. (242 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
SH2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa)
PTGFRProstaglandin F2-alpha receptor isoform a; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
LOC710149Ig-like domain-containing protein. (228 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (622 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1317 aa)
TPCN2Two pore segment channel 2. (823 aa)
GNALUncharacterized protein. (450 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (261 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (524 aa)
MCOLN2Mucolipin 2. (586 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (213 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
ENSMMUP00000076578Ig-like domain-containing protein. (275 aa)
PDE1CPhosphodiesterase. (793 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (283 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
HRCHistidine rich calcium binding protein. (799 aa)
TACR3NK-3 receptor; Belongs to the G-protein coupled receptor 1 family. (463 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1299 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
GRM1Metabotropic glutamate receptor 1 isoform alpha. (1195 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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