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PIP4K2C PIP4K2C PLCE1 PLCE1 MTMR7 MTMR7 INPP5E INPP5E PIK3R2 PIK3R2 INPP4B INPP4B MTMR8 MTMR8 PLCB1 PLCB1 PIK3CA PIK3CA PIP5K1A PIP5K1A PLCG2 PLCG2 MTMR14 MTMR14 ITPKA ITPKA PTEN PTEN PIK3CB PIK3CB OCRL OCRL INPP5D INPP5D ITPK1 ITPK1 INPPL1 INPPL1 PIK3R1 PIK3R1 PLCB3 PLCB3 PI4KB PI4KB CDS2 CDS2 PLCD3 PLCD3 IP6K1 IP6K1 DGKQ DGKQ CALML5 CALML5 ITPKC ITPKC MTMR6 MTMR6 DGKB DGKB DGKG DGKG PI4KA PI4KA PLCZ1 PLCZ1 MTM1 MTM1 PIK3C2A PIK3C2A DGKH DGKH PRKCG PRKCG SYNJ2 SYNJ2 SYNJ1 SYNJ1 SACM1L SACM1L ITPR2 ITPR2 CDS1 CDS1 IP6K2 IP6K2 ITPR3 ITPR3 CALML6 CALML6 PIK3C3 PIK3C3 DGKI DGKI ITPR1 ITPR1 PI4K2A PI4K2A CDIPT CDIPT CALML3 CALML3 DGKE DGKE PI4K2B PI4K2B PIP4K2B PIP4K2B DGKZ DGKZ IMPA1 IMPA1 PLCG1 PLCG1 DGKK DGKK LOC717098 LOC717098 PIK3R3 PIK3R3 INPP5F INPP5F IPPK IPPK PRKCB PRKCB PLCB4 PLCB4 PIP4P1 PIP4P1 MTMR4 MTMR4 PLCD1 PLCD1 PPIP5K2 PPIP5K2 PIK3C2G PIK3C2G IPMK IPMK PIK3CD PIK3CD PLCB2 PLCB2 PIKFYVE PIKFYVE PRKCA PRKCA ITPKB ITPKB PIP5K1C PIP5K1C IMPAD1 IMPAD1 MTMR3 MTMR3 MTMR1 MTMR1 INPP5A INPP5A MTMR2 MTMR2 CALM2 CALM2 IMPA2 IMPA2 INPP1 INPP1 CALM3 CALM3 PIP5K1B PIP5K1B IP6K3 IP6K3 PIK3C2B PIK3C2B PIP4P2 PIP4P2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type-2 gamma isoform a. (421 aa)
PLCE1Phosphoinositide phospholipase C. (2317 aa)
MTMR7Myotubularin-related protein 7. (660 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (644 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
MTMR8Myotubularin related protein 8. (710 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type-1 alpha isoform 1. (561 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
MTMR14Myotubularin-related protein 14 isoform 2. (650 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PTENUncharacterized protein. (589 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform b. (893 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1208 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (611 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1315 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (834 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
DGKQDiacylglycerol kinase. (953 aa)
CALML5Calmodulin-like protein 5. (146 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
MTMR6Myotubularin related protein 6. (672 aa)
DGKBDiacylglycerol kinase. (803 aa)
DGKGDiacylglycerol kinase. (791 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2126 aa)
PLCZ1Phosphoinositide phospholipase C. (608 aa)
MTM1Myotubularin. (603 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
DGKHDiacylglycerol kinase. (1244 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
SYNJ2Synaptojanin 2. (1501 aa)
SYNJ1Synaptojanin 1. (1614 aa)
SACM1LUncharacterized protein. (587 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (549 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CALML6Calmodulin like 6. (181 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (908 aa)
DGKIDiacylglycerol kinase. (1100 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (480 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
DGKEDiacylglycerol kinase. (567 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (585 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
DGKZDiacylglycerol kinase. (1118 aa)
IMPA1Inositol-1-monophosphatase. (329 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
DGKKDiacylglycerol kinase. (1265 aa)
LOC717098Uncharacterized protein; Belongs to the histidine acid phosphatase family. (217 aa)
PIK3R3Uncharacterized protein. (507 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (536 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa)
MTMR4Uncharacterized protein. (1209 aa)
PLCD1Phosphoinositide phospholipase C. (777 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1278 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2110 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (718 aa)
IMPAD1Inositol monophosphatase domain containing 1. (384 aa)
MTMR3Myotubularin-related protein 3 isoform c. (1198 aa)
MTMR1Myotubularin related protein 1. (692 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (450 aa)
MTMR2Myotubularin-related protein 2 isoform 1. (643 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
INPP1Inositol polyphosphate-1-phosphatase. (522 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type-1 beta isoform 2. (540 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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