102 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CPEB2	Cytoplasmic polyadenylation element binding protein 2. (1037 aa)
	CDC23	Cell division cycle protein 23 homolog. (597 aa)
	ANAPC2	Anaphase-promoting complex subunit 2; Belongs to the cullin family. (822 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (668 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (499 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	LOC704010	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	YWHAZ	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	SMC3	Structural maintenance of chromosomes protein. (1196 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (471 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	CDC25C	Cell division cycle 25C. (507 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	AR	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (895 aa)
	PGR	Uncharacterized protein. (936 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (511 aa)
	MOS	Proto-oncogene serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (346 aa)
	SLK	STE20 like kinase. (1236 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
	PLK1	Serine/threonine-protein kinase PLK. (603 aa)
	CALML5	Calmodulin-like protein 5. (146 aa)
	STAG3	SCD domain-containing protein. (1342 aa)
	CDC27	Cell division cycle protein 27 homolog isoform 1. (830 aa)
	FBXO5	F-box protein 5. (448 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (293 aa)
	PRKACG	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (410 aa)
	ADCY4	Adenylate cyclase 4. (1299 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (735 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2120 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	PLCZ1	Phosphoinositide phospholipase C. (608 aa)
	SPDYE4	Uncharacterized protein. (237 aa)
	LOC718058	Uncharacterized protein. (307 aa)
	CCNB1	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
	ANAPC4	Anaphase promoting complex subunit 4. (981 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	CDC16	Cell division cycle protein 16 homolog. (620 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (313 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	AURKA	Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
	ANAPC5	Anaphase-promoting complex subunit 5 isoform a. (755 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
	CDC20	Cell division cycle protein 20 homolog. (499 aa)
	CDK2	Diacylglycerol kinase. (1053 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	CALML6	Calmodulin like 6. (181 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (758 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
	YWHAE	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (860 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1085 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (716 aa)
	BTRC	Uncharacterized protein. (629 aa)
	ADCY5	Adenylate cyclase 5. (1263 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	CALML3	Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (505 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
	SKP1-2	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (108 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (768 aa)
	CPEB1	Uncharacterized protein. (584 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	YWHAQ	14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
	PPP3R1	Uncharacterized protein. (171 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa)
	PTTG1	Securin. (202 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (718 aa)
	YWHAG	14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (809 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha. (622 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (2016 aa)
	MAD2L1	Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (599 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1243 aa)
	CDC26	Anaphase-promoting complex subunit CDC26. (85 aa)
	CALM2	Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (194 aa)
	ANAPC13	Anaphase-promoting complex subunit 13. (74 aa)
	CPEB4	Cytoplasmic polyadenylation element-binding protein 4. (729 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSMMUP00000069811	ENSMMUP00000059741	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.486
ADCY1	ADCY3	ENSMMUP00000069811	ENSMMUP00000049332	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	ADCY4	ENSMMUP00000069811	ENSMMUP00000027242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 4.	0.468
ADCY1	ADCY5	ENSMMUP00000069811	ENSMMUP00000052487	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5.	0.457
ADCY1	ADCY6	ENSMMUP00000069811	ENSMMUP00000064485	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.441
ADCY1	ADCY7	ENSMMUP00000069811	ENSMMUP00000075019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.509
ADCY1	ADCY8	ENSMMUP00000069811	ENSMMUP00000044242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.951
ADCY1	ADCY9	ENSMMUP00000069811	ENSMMUP00000068875	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	CALM2	ENSMMUP00000069811	ENSMMUP00000076065	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.936
ADCY1	CALM3	ENSMMUP00000069811	ENSMMUP00000076991	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3; Belongs to the calmodulin family.	0.942
ADCY1	CALML3	ENSMMUP00000069811	ENSMMUP00000053471	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	0.954
ADCY1	CALML5	ENSMMUP00000069811	ENSMMUP00000022969	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 5.	0.977
ADCY1	CALML6	ENSMMUP00000069811	ENSMMUP00000045683	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.943
ADCY1	CAMK2A	ENSMMUP00000069811	ENSMMUP00000068951	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha.	0.718
ADCY1	CAMK2B	ENSMMUP00000069811	ENSMMUP00000003272	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.761
ADCY1	CAMK2G	ENSMMUP00000069811	ENSMMUP00000028185	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.742
ADCY1	PRKACA	ENSMMUP00000069811	ENSMMUP00000054168	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.932
ADCY1	PRKACB	ENSMMUP00000069811	ENSMMUP00000059748	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.	0.940
ADCY1	PRKACG	ENSMMUP00000069811	ENSMMUP00000026815	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.	0.932
ADCY2	ADCY1	ENSMMUP00000059741	ENSMMUP00000069811	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.486