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| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (158 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (412 aa) |
| | TRAF3IP2 | SEFIR domain-containing protein. (572 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1212 aa) |
| | RASSF5 | Ras association domain family member 5. (418 aa) |
| | TSC2 | TSC complex subunit 2. (2057 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | GPR83 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (778 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | MRAS | Uncharacterized protein. (214 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | PTEN | Uncharacterized protein. (589 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MAMU-F | Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system. (348 aa) |
| | CCNA2 | Cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | CAPN2 | Calpain-2 catalytic subunit isoform 1; Belongs to the peptidase C2 family. (700 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | IGFBP3 | Insulin-like growth factor-binding protein 3 isoform b. (291 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1025 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (511 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa) |
| | CALML5 | Calmodulin-like protein 5. (146 aa) |
| | PPID | Peptidyl-prolyl cis-trans isomerase D. (370 aa) |
| | GATA4 | GATA binding protein 4. (443 aa) |
| | FOXM1 | Forkhead box protein M1 isoform 2. (770 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MCU | Mitochondrial calcium uniporter. (351 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (548 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform a. (524 aa) |
| | HRAS | Transforming protein p21. (189 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (409 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | RRAS | Ras-related protein R-Ras. (218 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | E2F4 | Transcription factor E2F4. (416 aa) |
| | FOXO3 | Forkhead box O3. (672 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa) |
| | NFKB1 | Uncharacterized protein. (977 aa) |
| | MAP2K3 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (467 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | CHEK1 | STT3 oligosaccharyltransferase complex catalytic subunit A. (768 aa) |
| | CHEK2 | Checkpoint kinase 2. (539 aa) |
| | HIPK1 | Uncharacterized protein. (1598 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1. (165 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (357 aa) |
| | CDK2 | Diacylglycerol kinase. (1053 aa) |
| | CCNA1 | Cyclin-A1 isoform a; Belongs to the cyclin family. (465 aa) |
| | VDAC3 | Uncharacterized protein. (299 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (315 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | RAD1 | Uncharacterized protein. (282 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | GADD45G | Cytokine-responsive protein CR6. (159 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1141 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (767 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (344 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | RB1 | Retinoblastoma-associated protein. (928 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1411 aa) |
| | BTRC | Uncharacterized protein. (629 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CALML3 | Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | MYBL2 | Myb-related protein B. (700 aa) |
| | E2F5 | E2F transcription factor 5. (346 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1362 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (542 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (594 aa) |
| | MAP2K6 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (961 aa) |
| | PPP3R1 | Uncharacterized protein. (171 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (399 aa) |
| | HIPK3 | Homeodomain-interacting protein kinase 3 isoform 1. (1215 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (271 aa) |
| | LOC720132 | Major histocompatibility complex, class I, AG; Belongs to the MHC class I family. (339 aa) |
| | RHEB | Uncharacterized protein. (249 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (407 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | ZFP36L2 | Zinc finger protein 36, C3H1 type-like 2. (492 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | RRAS2 | Ras-related protein R-Ras2 isoform a. (204 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) |
| | LOC106995979 | Histone-binding protein RBBP4 isoform a. (425 aa) |
| | CAPN1 | Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (714 aa) |
| | CALM2 | Uncharacterized protein; Belongs to the calmodulin family. (204 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (308 aa) |
| | CALM3 | Calmodulin 3; Belongs to the calmodulin family. (194 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) |
| | CCND1 | Uncharacterized protein; Belongs to the cyclin family. (303 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (2379 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (943 aa) |
| | LOC697938 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | LIN52 | Protein lin-52 homolog. (116 aa) |
