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| | PDE3B | Phosphodiesterase. (1117 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | RYR2 | Ryanodine receptor 2. (4967 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (412 aa) |
| | RYR1 | Ryanodine receptor 1. (4928 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa) |
| | RPS6KB2 | Non-specific serine/threonine protein kinase. (512 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (884 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa) |
| | MRAS | Uncharacterized protein. (214 aa) |
| | SPP1 | Secreted phosphoprotein 1. (314 aa) |
| | ADCY10 | Adenylate cyclase 10. (1609 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | APLNR | Apelin receptor; Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. P [...] (380 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (280 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa) |
| | LOC712274 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa) |
| | NOTCH3 | Notch receptor 3. (2321 aa) |
| | NOS1 | Nitric oxide synthase 1. (1468 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | MYL3 | Myosin light chain 3. (254 aa) |
| | MYLK | Myosin light chain kinase. (1914 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform 1. (331 aa) |
| | GNA13 | G protein subunit alpha 13. (409 aa) |
| | MEF2D | Myocyte-specific enhancer factor 2D. (521 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | CALML5 | Calmodulin-like protein 5. (146 aa) |
| | ACTA2 | Uncharacterized protein. (396 aa) |
| | LIPE | Lipase E, hormone sensitive type. (1072 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | TFAM | Transcription factor A, mitochondrial. (248 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa) |
| | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | ADCY4 | Adenylate cyclase 4. (1299 aa) |
| | HRAS | Transforming protein p21. (189 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | TTC33 | Non-specific serine/threonine protein kinase. (581 aa) |
| | RRAS | Ras-related protein R-Ras. (218 aa) |
| | SPHK2 | DAGKc domain-containing protein. (669 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C isoform 1. (473 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (908 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | MEF2B | MADS-box domain-containing protein. (490 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | GABARAPL1 | Uncharacterized protein. (146 aa) |
| | ADCY5 | Adenylate cyclase 5. (1263 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CALML3 | Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa) |
| | MEF2A | Myocyte-specific enhancer factor 2A isoform 2. (503 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | RYR3 | Ryanodine receptor 3. (4870 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | MYL2 | Myosin light chain 2. (166 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (594 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (818 aa) |
| | LOC702827 | Uncharacterized protein. (117 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1123 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa) |
| | MYLK2 | Myosin light chain kinase 2. (603 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | CAMK4 | Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (473 aa) |
| | PLIN1 | Perilipin 1. (597 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa) |
| | MYLK4 | Myosin light chain kinase family member 4. (541 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | NRF1 | Nuclear respiratory factor 1. (582 aa) |
| | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (407 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa) |
| | RRAS2 | Ras-related protein R-Ras2 isoform a. (204 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa) |
| | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa) |
| | LOC719662 | Guanylate cyclase domain-containing protein. (1263 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa) |
| | CALM2 | Uncharacterized protein; Belongs to the calmodulin family. (204 aa) |
| | CALM3 | Calmodulin 3; Belongs to the calmodulin family. (194 aa) |
| | BECN2 | Beclin 2. (431 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa) |
| | CCND1 | Uncharacterized protein; Belongs to the cyclin family. (303 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1299 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
