STRINGSTRING
P2RY12 P2RY12 COL1A1 COL1A1 GP1BA GP1BA PIK3R2 PIK3R2 ITGB3 ITGB3 PLA2G4B PLA2G4B STIM1 STIM1 PLCB1 PLCB1 FCER1G FCER1G PIK3CA PIK3CA PLCG2 PLCG2 PIK3R5 PIK3R5 GNAI3 GNAI3 P2RX1 P2RX1 MAPK14 MAPK14 PIK3CB PIK3CB LOC705671 LOC705671 LOC694289 LOC694289 PRKG1 PRKG1 PIK3R1 PIK3R1 MAPK1 MAPK1 ITGA2B ITGA2B PTGS1 PTGS1 FERMT3 FERMT3 PLCB3 PLCB3 PPP1CC PPP1CC MAPK11 MAPK11 PLA2G4C PLA2G4C MYLK MYLK GNA13 GNA13 PPP1CA PPP1CA ITGB1 ITGB1 RASGRP1 RASGRP1 PRKCZ PRKCZ PPP1R12A PPP1R12A PRKG2 PRKG2 AKT3 AKT3 GNAI2 GNAI2 SRC SRC PRKACG PRKACG NOS3 NOS3 PPP1CB PPP1CB ADCY4 ADCY4 FGB FGB FGA FGA FGG FGG PLA2G4A PLA2G4A GNAI1 GNAI1 PLA2G4F PLA2G4F PIK3R6 PIK3R6 VAMP8 VAMP8 ROCK2 ROCK2 P2RY1 P2RY1 ITPR2 ITPR2 BTK BTK GP1BB GP1BB ITPR3 ITPR3 ACTG1 ACTG1 ADCY8 ADCY8 RHOA RHOA COL3A1 COL3A1 ITPR1 ITPR1 ROCK1 ROCK1 ADCY3 ADCY3 PLA2G4E PLA2G4E TLN2 TLN2 ORAI1 ORAI1 ARHGAP35 ARHGAP35 LOC106994860 LOC106994860 LYN LYN ADCY5 ADCY5 GUCY1B1 GUCY1B1 RAP1B RAP1B ITGA2 ITGA2 MAPK3 MAPK3 VWF VWF PLA2G4D PLA2G4D PRKACA PRKACA ARHGEF12 ARHGEF12 F2R F2R LCP2 LCP2 PTGIR PTGIR TLN1 TLN1 AKT2 AKT2 ADCY2 ADCY2 PRKACB PRKACB PIK3R3 PIK3R3 COL1A2 COL1A2 AKT1 AKT1 GNAQ GNAQ MYLK2 MYLK2 PLCB4 PLCB4 GP9 GP9 SYK SYK ADCY6 ADCY6 RASGRP2 RASGRP2 MYLK4 MYLK4 PIK3CG PIK3CG PIK3CD PIK3CD PLCB2 PLCB2 ADCY9 ADCY9 PRKCI PRKCI ADCY1 ADCY1 APBB1IP APBB1IP RAP1A RAP1A F2RL3 F2RL3 GUCY1A2 GUCY1A2 GP5 GP5 ADCY7 ADCY7 GUCY1A1 GUCY1A1 TBXA2R TBXA2R FCGR2A FCGR2A MYL12A MYL12A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
P2RY12p2Y purinoceptor 12. (342 aa)
COL1A1Collagen alpha-1(I) chain preproprotein. (1464 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (754 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
PLA2G4BPhospholipase A2. (1012 aa)
STIM1Stromal interaction molecule 1. (684 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (884 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC705671Uncharacterized protein. (398 aa)
LOC694289Uncharacterized protein. (394 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
FERMT3Fermitin family member 3. (744 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
PLA2G4CPhospholipase A2 group IVC. (564 aa)
MYLKMyosin light chain kinase. (1914 aa)
GNA13G protein subunit alpha 13. (409 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
RASGRP1RAS guanyl releasing protein 1. (826 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
PRKG2cGMP-dependent protein kinase. (781 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
SRCTyrosine-protein kinase. (644 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (928 aa)
FGGFibrinogen gamma chain. (437 aa)
PLA2G4APhospholipase A2. (749 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PLA2G4FPhospholipase A2. (849 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
BTKTyrosine-protein kinase. (659 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
RHOARas homolog family member A. (209 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1466 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PLA2G4EPhospholipase A2. (891 aa)
TLN2Talin 2. (2547 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (301 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
LOC106994860IG domain-containing protein. (241 aa)
LYNTyrosine-protein kinase. (577 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
RAP1BRas-related protein Rap-1b isoform 1. (184 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
VWFUncharacterized protein. (2888 aa)
PLA2G4DPhospholipase A2. (822 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
TLN1Talin 1. (2558 aa)
AKT2AKT serine/threonine kinase 2. (594 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
PIK3R3Uncharacterized protein. (507 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
MYLK2Myosin light chain kinase 2. (603 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
GP9Uncharacterized protein. (246 aa)
SYKTyrosine-protein kinase. (635 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
RASGRP2RAS guanyl-releasing protein 2. (609 aa)
MYLK4Myosin light chain kinase family member 4. (541 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (674 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (733 aa)
GP5Glycoprotein V platelet. (561 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
FCGR2AUncharacterized protein. (316 aa)
MYL12AUncharacterized protein. (232 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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