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AZI2 | 5-azacytidine induced 2. (394 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (384 aa) | ||||
IRF7 | Interferon regulatory factor 7. (504 aa) | ||||
TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (513 aa) | ||||
STING1 | Stimulator of interferon protein. (379 aa) | ||||
NLRX1 | NLR family member X1. (972 aa) | ||||
CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) | ||||
DDX58 | Putative ATP-dependent RNA helicase DDX58. (925 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
DHX58 | DExH-box helicase 58. (678 aa) | ||||
MAVS | Mitochondrial antiviral-signaling protein isoform 1. (541 aa) | ||||
TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
CXCL10 | C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (379 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
LOC694631 | Uncharacterized protein. (190 aa) | ||||
NFKBIB | NF-kappa-B inhibitor beta isoform a. (356 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7. (620 aa) | ||||
NFKB1 | Uncharacterized protein. (977 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. (716 aa) | ||||
SIKE1 | Suppressor of IKBKE 1. (211 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (489 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (464 aa) | ||||
LOC710751 | Uncharacterized protein. (189 aa) | ||||
DDX3X | ATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
OTUD5 | OTU deubiquitinase 5. (566 aa) | ||||
RNF125 | E3 ubiquitin-protein ligase RNF125. (232 aa) | ||||
TKFC | Triokinase and FMN cyclase. (598 aa) | ||||
CASP10 | Caspase 10; Belongs to the peptidase C14A family. (520 aa) | ||||
NFKBIA | NF-kappa-B inhibitor alpha. (317 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
TANK | TRAF family member-associated NF-kappa-B activator isoform a. (425 aa) | ||||
IFNK | Interferon kappa. (207 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
LOC710568 | Interferon alpha 16. (189 aa) | ||||
IFNA14 | Interferon alpha 14. (189 aa) | ||||
IFNW1 | Interferon alpha-II-1. (195 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) | ||||
IFNA6 | Interferon alpha-6. (189 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) | ||||
TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (308 aa) | ||||
CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
IFNA10 | Uncharacterized protein. (189 aa) | ||||
IFNA8 | Interferon alpha-8. (189 aa) | ||||
PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) | ||||
TBKBP1 | TBK1 binding protein 1. (669 aa) | ||||
IFNA13 | Uncharacterized protein. (190 aa) | ||||
ISG15 | Ubiquitin-like protein ISG15. (165 aa) | ||||
COIL | Tripartite motif containing 25. (899 aa) | ||||
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1508 aa) |