STRINGSTRING
HCK HCK SCIN SCIN PLA2G6 PLA2G6 PIK3R2 PIK3R2 PLA2G4B PLA2G4B PIK3CA PIK3CA PIP5K1A PIP5K1A PLCG2 PLCG2 RPS6KB2 RPS6KB2 ARPC3 ARPC3 NCF1 NCF1 PIK3CB PIK3CB INPP5D INPP5D MARCKSL1 MARCKSL1 INPPL1 INPPL1 PIK3R1 PIK3R1 ASAP1 ASAP1 MAPK1 MAPK1 ENSMMUP00000017083 ENSMMUP00000017083 GSN GSN PLA2G4C PLA2G4C PRKCE PRKCE DNM2 DNM2 MAP2K1 MAP2K1 VAV2 VAV2 DOCK1 DOCK1 PAK1 PAK1 AKT3 AKT3 RAC1 RAC1 PLA2G4A PLA2G4A ARPC2 ARPC2 PLD1 PLD1 PRKCG PRKCG SPHK2 SPHK2 LIMK1 LIMK1 PLA2G4F PLA2G4F MYO10 MYO10 FCGR1A FCGR1A CDC42 CDC42 MARCKS MARCKS CRK CRK ASAP2 ASAP2 SPHK1 SPHK1 ASAP3 ASAP3 FCGR3 FCGR3 PLA2G4E PLA2G4E LYN LYN MAPK3 MAPK3 PTPRC PTPRC PLA2G4D PLA2G4D WAS WAS ARPC5L ARPC5L RAC2 RAC2 PLCG1 PLCG1 RAF1 RAF1 CFL1 CFL1 VAV1 VAV1 GAB2 GAB2 AKT2 AKT2 PIK3R3 PIK3R3 AKT1 AKT1 PRKCB PRKCB WASF1 WASF1 WASF3 WASF3 PLD2 PLD2 SYK SYK LOC106999628 LOC106999628 PIK3CD PIK3CD PRKCA PRKCA PIP5K1C PIP5K1C VAV3 VAV3 ARPC1A ARPC1A WASF2 WASF2 CFL2 CFL2 PRKCD PRKCD PLPP3 PLPP3 PIP5K1B PIP5K1B ARF6 ARF6 PLPP1 PLPP1 FCGR2A FCGR2A LIMK2 LIMK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCKTyrosine-protein kinase. (504 aa)
SCINScinderin. (715 aa)
PLA2G6Phospholipase A2 group VI. (935 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type-1 alpha isoform 1. (561 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
RPS6KB2Non-specific serine/threonine protein kinase. (512 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1208 aa)
MARCKSL1MARCKS-related protein. (195 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1315 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1221 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSMMUP00000017083Ig-like domain-containing protein. (183 aa)
GSNGelsolin. (809 aa)
PLA2G4CPhospholipase A2 group IVC. (564 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
DNM2Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform 1. (878 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1883 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RAC1Uncharacterized protein. (212 aa)
PLA2G4APhospholipase A2. (749 aa)
ARPC2Actin related protein 2/3 complex subunit 2. (603 aa)
PLD1Phospholipase. (1086 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
SPHK2DAGKc domain-containing protein. (669 aa)
LIMK1LIM domain kinase 1 isoform 1. (647 aa)
PLA2G4FPhospholipase A2. (849 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2058 aa)
FCGR1AFCGRI variant 1. (357 aa)
CDC42Cell division control protein 42 homolog isoform 1. (191 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (331 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
SPHK1Sphingosine kinase 1. (470 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
FCGR3Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Binds IgG1 and IgG2 (By similarity). (277 aa)
PLA2G4EPhospholipase A2. (891 aa)
LYNTyrosine-protein kinase. (577 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
PLA2G4DPhospholipase A2. (822 aa)
WASWASP actin nucleation promoting factor. (503 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
RAF1Uncharacterized protein. (668 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (177 aa)
VAV1Vav guanine nucleotide exchange factor 1. (928 aa)
GAB2GRB2 associated binding protein 2. (677 aa)
AKT2AKT serine/threonine kinase 2. (594 aa)
PIK3R3Uncharacterized protein. (507 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
WASF3Wiskott-Aldrich syndrome protein family member 3. (502 aa)
PLD2Phospholipase. (933 aa)
SYKTyrosine-protein kinase. (635 aa)
LOC106999628Ig-like domain-containing protein. (242 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (718 aa)
VAV3Vav guanine nucleotide exchange factor 3. (1128 aa)
ARPC1AUncharacterized protein. (684 aa)
WASF2WASP family member 2. (498 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
PRKCDProtein kinase C. (729 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type-1 beta isoform 2. (540 aa)
ARF6Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (190 aa)
PLPP1Lipid phosphate phosphohydrolase 1 isoform 2. (285 aa)
FCGR2AUncharacterized protein. (316 aa)
LIMK2LIM domain kinase 2. (793 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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