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GNG13 GNG13 RYR2 RYR2 CAMK2B CAMK2B RYR1 RYR1 GNB4 GNB4 PLCB1 PLCB1 GRIA4 GRIA4 GNB3 GNB3 ADCYAP1R1 ADCYAP1R1 GNAI3 GNAI3 GRIN2D GRIN2D RASD1 RASD1 KCNJ3 KCNJ3 GRIA3 GRIA3 LOC694289 LOC694289 ADCY10 ADCY10 PRKG1 PRKG1 MAPK1 MAPK1 PLCB3 PLCB3 CACNA1C CACNA1C NOS1 NOS1 GNB5 GNB5 CALML5 CALML5 MTNR1A MTNR1A PER2 PER2 GRIN2B GRIN2B PRKG2 PRKG2 GNAO1 GNAO1 GNAI2 GNAI2 PRKACG PRKACG ADCY4 ADCY4 CAMK2G CAMK2G PER1 PER1 GNG5 GNG5 GNAI1 GNAI1 PRKCG PRKCG CACNA1G CACNA1G KCNJ6 KCNJ6 CACNA1I CACNA1I CREB1 CREB1 GRIN1 GRIN1 RPS6KA5 RPS6KA5 ITPR3 ITPR3 ADCY8 ADCY8 CALML6 CALML6 GRIN2A GRIN2A ITPR1 ITPR1 GNGT1 GNGT1 ADCY3 ADCY3 CACNA1D CACNA1D GNG11 GNG11 GNG3 GNG3 ADCY5 ADCY5 GUCY1B1 GUCY1B1 MAPK3 MAPK3 CALML3 CALML3 PRKACA PRKACA PER3 PER3 RYR3 RYR3 CACNA1H CACNA1H ADCY2 ADCY2 PRKACB PRKACB GRIA1 GRIA1 GRIA2 GRIA2 GNAQ GNAQ PRKCB PRKCB MTNR1B MTNR1B PLCB4 PLCB4 ADCY6 ADCY6 KCNJ5 KCNJ5 GNB1 GNB1 KCNJ9 KCNJ9 GNG7 GNG7 PLCB2 PLCB2 ADCY9 ADCY9 CAMK2A CAMK2A ADCYAP1 ADCYAP1 ADCY1 ADCY1 PRKCA PRKCA GRIN2C GRIN2C GNB2 GNB2 LOC719662 LOC719662 FOS FOS GUCY1A2 GUCY1A2 ADCY7 ADCY7 GUCY1A1 GUCY1A1 CALM2 CALM2 CALM3 CALM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (668 aa)
RYR1Ryanodine receptor 1. (4928 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (884 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (538 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
RASD1Dexamethasone-induced Ras-related protein 1 isoform 1 proprotein. (279 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1. (501 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
LOC694289Uncharacterized protein. (394 aa)
ADCY10Adenylate cyclase 10. (1609 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
GNB5G protein subunit beta 5. (395 aa)
CALML5Calmodulin-like protein 5. (146 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
PER2Period circadian regulator 2. (1254 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
PRKG2cGMP-dependent protein kinase. (781 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (735 aa)
PER1Vesicle-associated membrane protein 2. (1369 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2111 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CALML6Calmodulin like 6. (181 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
PER3Period circadian regulator 3. (1178 aa)
RYR3Ryanodine receptor 3. (4870 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2352 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
GRIA1Uncharacterized protein. (916 aa)
GRIA2Uncharacterized protein. (883 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MTNR1BUncharacterized protein. (88 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (469 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (468 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (622 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (198 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1317 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
LOC719662Guanylate cyclase domain-containing protein. (1263 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (733 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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