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| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | KCNJ14 | Potassium voltage-gated channel subfamily J member 14. (436 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (412 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (668 aa) |
| | GNA11 | Guanine nucleotide-binding protein subunit alpha-11. (359 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | CHAT | Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (737 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (884 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) |
| | KCNJ3 | G protein-activated inward rectifier potassium channel 1. (501 aa) |
| | CHRNB4 | Cholinergic receptor nicotinic beta 4 subunit. (492 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1970 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | KCNQ3 | Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family. (872 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2338 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) |
| | CHRM5 | Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. (532 aa) |
| | JAK2 | Tyrosine-protein kinase. (1137 aa) |
| | KCNQ5 | Potassium voltage-gated channel subfamily Q member 5. (951 aa) |
| | KCNQ2 | Potassium voltage-gated channel subfamily Q member 2. (1110 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 1. (520 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CHRM1 | Muscarinic acetylcholine receptor M1; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. (460 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa) |
| | KCNQ4 | Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa) |
| | GNAO1 | Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (603 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa) |
| | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa) |
| | ADCY4 | Adenylate cyclase 4. (1299 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (735 aa) |
| | CHRM3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa) |
| | HRAS | Transforming protein p21. (189 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | CHRNA3 | Cholinergic receptor nicotinic alpha 3 subunit. (497 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) |
| | KCNJ6 | G protein-activated inward rectifier potassium channel 2. (423 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa) |
| | LOC719678 | Uncharacterized protein. (626 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | SLC18A3 | Solute carrier family 18 member A3. (532 aa) |
| | CHRNA6 | Cholinergic receptor nicotinic alpha 6 subunit. (494 aa) |
| | CHRM4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa) |
| | ADCY5 | Adenylate cyclase 5. (1263 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa) |
| | KCNJ4 | Potassium voltage-gated channel subfamily J member 4. (445 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (594 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | CAMK4 | Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (473 aa) |
| | ACHE | Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (848 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3. (372 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa) |
| | CHRM2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (492 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha. (622 aa) |
| | ATF4 | BZIP domain-containing protein. (351 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa) |
| | BCL2 | BCL2 apoptosis regulator. (241 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa) |
| | SLC5A7 | Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa) |
| | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa) |
| | FOS | V-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa) |
| | KCNJ12 | Uncharacterized protein. (558 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa) |
| | KCNJ2 | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...] (427 aa) |
| | CHRNB2 | Neuronal acetylcholine receptor subunit beta-2. (502 aa) |
