STRINGSTRING
GNAZ GNAZ KRAS KRAS IGF1 IGF1 GRID2 GRID2 RYR1 RYR1 GNA11 GNA11 CACNA1A CACNA1A PLA2G4B PLA2G4B PLCB1 PLCB1 GNAI3 GNAI3 GRIA3 GRIA3 LOC694289 LOC694289 PRKG1 PRKG1 IGF1R IGF1R MAPK1 MAPK1 PLCB3 PLCB3 NOS1 NOS1 PLA2G4C PLA2G4C GNA13 GNA13 MAP2K1 MAP2K1 PRKG2 PRKG2 GNAO1 GNAO1 GNAI2 GNAI2 PPP2CB PPP2CB PLA2G4A PLA2G4A CRH CRH HRAS HRAS PPP2R1A PPP2R1A GNAI1 GNAI1 PRKCG PRKCG PLA2G4F PLA2G4F ITPR2 ITPR2 ITPR3 ITPR3 BRAF BRAF ITPR1 ITPR1 PLA2G4E PLA2G4E PPP2R1B PPP2R1B NRAS NRAS GNA12 GNA12 LYN LYN GUCY1B1 GUCY1B1 MAPK3 MAPK3 PLA2G4D PLA2G4D RAF1 RAF1 GRIA1 GRIA1 GRIA2 GRIA2 GNAQ GNAQ PRKCB PRKCB PLCB4 PLCB4 PLCB2 PLCB2 MAP2K2 MAP2K2 PRKCA PRKCA PPP1R17 PPP1R17 GUCY1A2 GUCY1A2 ARAF ARAF GUCY1A1 GUCY1A1 GRM1 GRM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
KRASKRAS proto-oncogene, GTPase. (412 aa)
IGF1Insulin like growth factor 1. (208 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
RYR1Ryanodine receptor 1. (4928 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
LOC694289Uncharacterized protein. (394 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
PLA2G4CPhospholipase A2 group IVC. (564 aa)
GNA13G protein subunit alpha 13. (409 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PRKG2cGMP-dependent protein kinase. (781 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PLA2G4APhospholipase A2. (749 aa)
CRHCorticotropin releasing hormone. (196 aa)
HRASTransforming protein p21. (189 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
PLA2G4FPhospholipase A2. (849 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
PLA2G4EPhospholipase A2. (891 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (716 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNA12G protein subunit alpha 12. (463 aa)
LYNTyrosine-protein kinase. (577 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PLA2G4DPhospholipase A2. (822 aa)
RAF1Uncharacterized protein. (668 aa)
GRIA1Uncharacterized protein. (916 aa)
GRIA2Uncharacterized protein. (883 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17 isoform 1. (155 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (733 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GRM1Metabotropic glutamate receptor 1 isoform alpha. (1195 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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