(54 nodes) Regulation of lipolysis in adipocytes network (Macaca mulatta)

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second shell of interactors

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Your Input:
	PDE3B	Phosphodiesterase. (1117 aa)
	ABHD5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5. (349 aa)
	ADRB2	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (415 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	NPR1	Guanylate cyclase. (1061 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	LOC694289	Uncharacterized protein. (394 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	FABP4	Adipocyte-type fatty acid-binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PTGS1	Prostaglandin-endoperoxide synthase 1. (599 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	PTGER3	Prostaglandin E receptor 3. (460 aa)
	LIPE	Lipase E, hormone sensitive type. (1072 aa)
	PLAAT2	Phospholipase A and acyltransferase 3. (256 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	PRKG2	cGMP-dependent protein kinase. (781 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	FABP9	Uncharacterized protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	GNAI2	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
	PRKACG	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
	ADCY4	Adenylate cyclase 4. (1299 aa)
	IRS2	Insulin receptor substrate 2. (1394 aa)
	GNAI1	G protein subunit alpha i1. (422 aa)
	ADRB3	Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (418 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	IRS1	Insulin receptor substrate 1. (1253 aa)
	ADRB1	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (478 aa)
	MGLL	Monoglyceride lipase. (352 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	ADCY5	Adenylate cyclase 5. (1263 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
	AKT2	AKT serine/threonine kinase 2. (594 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
	PIK3R3	Uncharacterized protein. (507 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	AQP7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (395 aa)
	PLIN1	Perilipin 1. (597 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (601 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	NPY	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. (169 aa)
	TSHB	Thyroid stimulating hormone subunit beta. (158 aa)
	CGA	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (161 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
	NPY1R	Neuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD5	LIPE	ENSMMUP00000001382	ENSMMUP00000023553	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Lipase E, hormone sensitive type.	0.704
ABHD5	MGLL	ENSMMUP00000001382	ENSMMUP00000048181	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Monoglyceride lipase.	0.468
ABHD5	PLIN1	ENSMMUP00000001382	ENSMMUP00000062850	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Perilipin 1.	0.899
ABHD5	PNPLA2	ENSMMUP00000001382	ENSMMUP00000067557	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Patatin like phospholipase domain containing 2.	0.969
ADCY1	ADCY2	ENSMMUP00000069811	ENSMMUP00000059741	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.486
ADCY1	ADCY3	ENSMMUP00000069811	ENSMMUP00000049332	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	ADCY4	ENSMMUP00000069811	ENSMMUP00000027242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 4.	0.468
ADCY1	ADCY5	ENSMMUP00000069811	ENSMMUP00000052487	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5.	0.457
ADCY1	ADCY6	ENSMMUP00000069811	ENSMMUP00000064485	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.441
ADCY1	ADCY7	ENSMMUP00000069811	ENSMMUP00000075019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.509
ADCY1	ADCY8	ENSMMUP00000069811	ENSMMUP00000044242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.951
ADCY1	ADCY9	ENSMMUP00000069811	ENSMMUP00000068875	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	AKT1	ENSMMUP00000069811	ENSMMUP00000061388	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.694
ADCY1	AKT2	ENSMMUP00000069811	ENSMMUP00000059674	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AKT serine/threonine kinase 2.	0.694
ADCY1	AKT3	ENSMMUP00000069811	ENSMMUP00000026292	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.694
ADCY1	GNAI1	ENSMMUP00000069811	ENSMMUP00000030898	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.809
ADCY1	GNAI2	ENSMMUP00000069811	ENSMMUP00000026482	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	0.802
ADCY1	GNAI3	ENSMMUP00000069811	ENSMMUP00000007669	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.809
ADCY1	LOC694289	ENSMMUP00000069811	ENSMMUP00000013436	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.968
ADCY1	NPPA	ENSMMUP00000069811	ENSMMUP00000010290	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Natriuretic peptide A.	0.463