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| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | COL1A1 | Collagen alpha-1(I) chain preproprotein. (1464 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (412 aa) |
| | MMP1 | Matrix metallopeptidase 1. (469 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | MMP13 | Matrix metallopeptidase 13. (471 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | VEGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (489 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (783 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) |
| | SHC1 | SHC-transforming protein 1 isoform 3. (584 aa) |
| | COL4A6 | Collagen type IV alpha 6 chain. (1705 aa) |
| | COL4A1 | Collagen type IV alpha 1 chain. (1669 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | LOC694289 | Uncharacterized protein. (394 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa) |
| | COL4A4 | Collagen type IV alpha 4 chain. (1692 aa) |
| | NOS1 | Nitric oxide synthase 1. (1468 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa) |
| | MMP9 | Uncharacterized protein. (707 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 1. (520 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | ACTA2 | Uncharacterized protein. (396 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | GNAO1 | Guanine nucleotide-binding protein G(O) subunit alpha isoform a. (354 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (603 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | ADCY4 | Adenylate cyclase 4. (1299 aa) |
| | HRAS | Transforming protein p21. (189 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1739 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | NFKB1 | Uncharacterized protein. (977 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa) |
| | RXFP4 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (373 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform 1. (217 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | COL3A1 | Collagen alpha-1(III) chain preproprotein. (1466 aa) |
| | EGFR | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa) |
| | SOS2 | Uncharacterized protein. (1332 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | SHC3 | Uncharacterized protein. (596 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa) |
| | MMP2 | 72 kDa type IV collagenase isoform a preproprotein. (660 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | ADCY5 | Adenylate cyclase 5. (1263 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | RLN2 | Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. (185 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (317 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa) |
| | SHC4 | Src-like proteiny 2 domain-containing-transforming protein C4. (630 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | COL4A5 | Collagen type IV alpha 5 chain. (1691 aa) |
| | ATF6B | Activating transcription factor 6 beta. (711 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (594 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1274 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | INSL5 | Insulin like 5. (135 aa) |
| | EDN1 | Preproendothelin-1. (211 aa) |
| | GNA15 | Uncharacterized protein. (414 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3. (372 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa) |
| | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa) |
| | RXFP3 | Relaxin family peptide receptor 3. (469 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1345 aa) |
| | ARRB2 | Arrestin beta 2. (575 aa) |
| | RLN3 | Relaxin 3. (166 aa) |
| | RXFP2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (753 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | LOC114675602 | IlGF domain-containing protein. (132 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa) |
| | ATF4 | BZIP domain-containing protein. (351 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa) |
| | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa) |
| | FOS | V-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1674 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (334 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa) |
| | ARRB1 | Arrestin beta 1. (529 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1299 aa) |
