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ATP1B4 ATP1B4 ADRB2 ADRB2 LPO LPO PLCB1 PLCB1 LOC694289 LOC694289 CAMP CAMP PRKG1 PRKG1 ATP2B3 ATP2B3 PLCB3 PLCB3 NOS1 NOS1 BST1 BST1 CD38 CD38 TRPV6 TRPV6 CALML5 CALML5 ATP1A2 ATP1A2 KCNMA1 KCNMA1 MUC7 MUC7 PRKG2 PRKG2 ATP2B2 ATP2B2 PRKACG PRKACG SLC4A2 SLC4A2 ADCY4 ADCY4 ATP1B1 ATP1B1 DMBT1 DMBT1 CHRM3 CHRM3 ATP2B1 ATP2B1 PRKCG PRKCG ADRB3 ADRB3 LOC713027 LOC713027 ITPR2 ITPR2 KCNN4 KCNN4 ITPR3 ITPR3 LOC698176 LOC698176 ADCY8 ADCY8 CALML6 CALML6 LYZ LYZ ITPR1 ITPR1 ADRB1 ADRB1 ADCY3 ADCY3 ATP1A3 ATP1A3 ATP1A1 ATP1A1 ADCY5 ADCY5 GUCY1B1 GUCY1B1 LOC703642 LOC703642 CALML3 CALML3 PRKACA PRKACA ADRA1A ADRA1A ATP1B2 ATP1B2 SLC9A1 SLC9A1 RYR3 RYR3 SLC12A2 SLC12A2 ADCY2 ADCY2 PRKACB PRKACB CST3 CST3 GNAQ GNAQ PRKCB PRKCB AMY2B AMY2B PLCB4 PLCB4 ADRA1D ADRA1D ADCY6 ADCY6 PLCB2 PLCB2 CST5 CST5 ATP1B3 ATP1B3 ADCY9 ADCY9 ADCY1 ADCY1 PRKCA PRKCA AQP5 AQP5 GUCY1A2 GUCY1A2 ADCY7 ADCY7 GUCY1A1 GUCY1A1 BEST2 BEST2 CALM2 CALM2 CALM3 CALM3 ATP2B4 ATP2B4 ADRA1B ADRA1B FXYD6 FXYD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (415 aa)
LPOLactoperoxidase. (712 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC694289Uncharacterized protein. (394 aa)
CAMPCathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. (173 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
BST1Bone marrow stromal cell antigen 1. (315 aa)
CD38ADP-ribosyl cyclase 1. (301 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (821 aa)
CALML5Calmodulin-like protein 5. (146 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] (1233 aa)
MUC7Mucin 7, secreted. (446 aa)
PRKG2cGMP-dependent protein kinase. (781 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
SLC4A2Anion exchange protein. (1238 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
DMBT1Uncharacterized protein. (278 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
ADRB3Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (418 aa)
LOC713027Alpha-amylase. (511 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC698176Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (194 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CALML6Calmodulin like 6. (181 aa)
LYZLysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. (148 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
ADRB1Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (478 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
LOC703642Cystatin domain-containing protein; Belongs to the cystatin family. (141 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
ADRA1AAdrenoceptor alpha 1A. (445 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (299 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
RYR3Ryanodine receptor 3. (4870 aa)
SLC12A2Solute carrier family 12 member 2. (1210 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
CST3Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity; Belongs to the cystatin family. (146 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
AMY2BAlpha-amylase. (511 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ADRA1DAdrenoceptor alpha 1D. (570 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
CST5Cystatin D; Belongs to the cystatin family. (143 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (403 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (733 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (509 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (174 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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