STRINGSTRING
PSMD2 PSMD2 MAPK9 MAPK9 PSMD12 PSMD12 FGF14 FGF14 RYR1 RYR1 PIK3R2 PIK3R2 RBPJL RBPJL PSMC2 PSMC2 CACNA1A CACNA1A ATG2B ATG2B ATG2A ATG2A MAPK8 MAPK8 SEM1-2 SEM1-2 PLCB1 PLCB1 PIK3CA PIK3CA GRIN2D GRIN2D PSMB5 PSMB5 MYOD1 MYOD1 XBP1 XBP1 WIPI1 WIPI1 PSMD4 PSMD4 ATP2A3 ATP2A3 PIK3CB PIK3CB ATXN10 ATXN10 GRIA3 GRIA3 OPA1 OPA1 PDYN PDYN RB1CC1 RB1CC1 PSMA4 PSMA4 AMBRA1 AMBRA1 TRAF2 TRAF2 PIK3R1 PIK3R1 PSMD1 PSMD1 PLCB3 PLCB3 PSMB6 PSMB6 PSMB2 PSMB2 NOP56 NOP56 VLDLR VLDLR ERN1 ERN1 PSMC3 PSMC3 PSMD9 PSMD9 GRIN3A GRIN3A PSMC4 PSMC4 NRBF2 NRBF2 PSMA7 PSMA7 GRIN2B GRIN2B KAT5 KAT5 PSMB1 PSMB1 AKT3 AKT3 PIK3R4 PIK3R4 SPTBN2 SPTBN2 PSMD3 PSMD3 MCU MCU PSMB4 PSMB4 OMA1 OMA1 TBPL2 TBPL2 PRKCG PRKCG KCNC3 KCNC3 PSMC1 PSMC1 F7ALC4_MACMU F7ALC4_MACMU TRPC3 TRPC3 ITPR2 ITPR2 DAB1 DAB1 GRIN1 GRIN1 MAPK10 MAPK10 VDAC3 VDAC3 SLC1A6 SLC1A6 PSMA8 PSMA8 ITPR3 ITPR3 ATP2A2 ATP2A2 ATXN2 ATXN2 PIK3C3 PIK3C3 GRIN2A GRIN2A RORA RORA TBP TBP ITPR1 ITPR1 PSMB3 PSMB3 PSMA6 PSMA6 ULK2 ULK2 GRIN3B GRIN3B PSMD14 PSMD14 MAP3K5 MAP3K5 PSMA2 PSMA2 RBPJ RBPJ PSMD8 PSMD8 CIC CIC ATXN3 ATXN3 RELN RELN AKT2 AKT2 PSMA3 PSMA3 GRIA1 GRIA1 PIK3R3 PIK3R3 GRIA2 GRIA2 AKT1 AKT1 GNAQ GNAQ PRKCB PRKCB PPIF PPIF PLCB4 PLCB4 ATXN1 ATXN1 PSMC5 PSMC5 SLC25A6 SLC25A6 KCND3 KCND3 PSMD7 PSMD7 SLC25A31 SLC25A31 SH2B1 SH2B1 TBPL1 TBPL1 PIK3CD PIK3CD PLCB2 PLCB2 ATG14 ATG14 PRKCA PRKCA BEAN1 BEAN1 GRIN2C GRIN2C PSMA1 PSMA1 PSMB7 PSMB7 TWNK TWNK ATXN1L ATXN1L CYCS CYCS MTOR MTOR GTF2B GTF2B AFG3L2 AFG3L2 ATXN2L ATXN2L ATG101 ATG101 VDAC2 VDAC2 BECN2 BECN2 ULK1 ULK1 VDAC1 VDAC1 PUM1 PUM1 SP1 SP1 PSMA5 PSMA5 GRM1 GRM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (476 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
RYR1Ryanodine receptor 1. (4928 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (517 aa)
PSMC226S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family. (433 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa)
ATG2BAutophagy related 2B. (2078 aa)
ATG2AAutophagy related 2A. (1932 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
SEM1-226S proteasome complex subunit DSS1. (70 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
PSMB5Proteasome subunit beta. (263 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
XBP1X-box binding protein 1. (376 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (437 aa)
PSMD4VWFA domain-containing protein. (400 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1092 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ATXN10Uncharacterized protein. (545 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1071 aa)
PDYNProenkephalin-B preproprotein. (253 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform 1. (1594 aa)
PSMA4Proteasome subunit alpha type. (300 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1238 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (513 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1120 aa)
PSMB6Proteasome subunit beta. (285 aa)
PSMB2Proteasome subunit beta. (201 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
VLDLRVery low density lipoprotein receptor. (947 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (978 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
PSMC426S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family. (418 aa)
NRBF2Nuclear receptor-binding factor 2. (287 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
PSMB1Proteasome subunit beta. (241 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
MCUMitochondrial calcium uniporter. (351 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
OMA1OMA1 zinc metallopeptidase. (555 aa)
TBPL2TATA-box binding protein like 2. (376 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (757 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
F7ALC4_MACMUAAA domain-containing protein; Belongs to the AAA ATPase family. (360 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
DAB1DAB adaptor protein 1. (555 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
VDAC3Uncharacterized protein. (299 aa)
SLC1A6Amino acid transporter. (564 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1011 aa)
ATXN2Ataxin 2. (1330 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (908 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
RORARAR related orphan receptor A. (555 aa)
TBPTATA-box binding protein. (326 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
PSMB3Proteasome subunit beta. (261 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1025 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1042 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1483 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
RBPJUncharacterized protein. (500 aa)
PSMD8CSN8_PSD8_EIF3K domain-containing protein. (364 aa)
CICCapicua transcriptional repressor. (2517 aa)
ATXN3Ataxin-3 reference isoform. (360 aa)
RELNReelin. (3460 aa)
AKT2AKT serine/threonine kinase 2. (594 aa)
PSMA3Proteasome subunit alpha type. (267 aa)
GRIA1Uncharacterized protein. (916 aa)
PIK3R3Uncharacterized protein. (507 aa)
GRIA2Uncharacterized protein. (883 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PPIFPeptidylprolyl isomerase F. (309 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
ATXN1Ataxin 1. (817 aa)
PSMC526S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family. (406 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (399 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (655 aa)
PSMD7MPN domain-containing protein. (323 aa)
SLC25A31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
SH2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
ATG14Autophagy related 14. (492 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
BEAN1Brain expressed associated with NEDD4 1. (259 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1317 aa)
PSMA1Proteasome endopeptidase complex. (301 aa)
PSMB7Proteasome subunit beta. (277 aa)
TWNKTwinkle protein, mitochondrial isoform A. (684 aa)
ATXN1LAXH domain-containing protein. (691 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
GTF2BGeneral transcription factor IIB. (312 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (800 aa)
ATXN2LAtaxin 2 like. (1099 aa)
ATG101Autophagy-related protein 101. (218 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
BECN2Beclin 2. (431 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (283 aa)
PUM1Pumilio RNA binding family member 1. (1188 aa)
SP1Uncharacterized protein. (845 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
GRM1Metabotropic glutamate receptor 1 isoform alpha. (1195 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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