STRINGSTRING
CDKN2B CDKN2B CDC23 CDC23 ANAPC2 ANAPC2 MAPK9 MAPK9 KRAS KRAS NFKB2 NFKB2 BUB3 BUB3 PIK3R2 PIK3R2 MMP7 MMP7 STAT5B STAT5B CD40 CD40 MAPK8 MAPK8 ELK4 ELK4 ATM ATM ANAPC10 ANAPC10 MSX2 MSX2 CRTC2 CRTC2 PIK3CA PIK3CA IL2RB IL2RB BCL2L1 BCL2L1 TSPO TSPO CRTC1 CRTC1 MAP3K14 MAP3K14 ATR ATR PTEN PTEN TP53 TP53 PIK3CB PIK3CB MAMU-F MAMU-F LTA LTA CRTC3 CRTC3 ETS2 ETS2 ICAM1 ICAM1 CCNA2 CCNA2 TGFBR2 TGFBR2 TERT TERT JAK3 JAK3 PIK3R1 PIK3R1 E2F2 E2F2 RANBP3 RANBP3 TGFB3 TGFB3 CANX CANX MAPK1 MAPK1 RELB RELB PPP3CC PPP3CC MYC MYC KAT2A KAT2A IL2RA IL2RA SPI1 SPI1 PPP3CB PPP3CB CREB3L2 CREB3L2 MAP2K1 MAP2K1 CSF2 CSF2 CD3D CD3D IL2RG IL2RG SMAD4 SMAD4 JAK1 JAK1 CREB3L1 CREB3L1 CDC27 CDC27 CDKN2C CDKN2C IL15 IL15 MAMU-DPA MAMU-DPA ELK1 ELK1 KAT5 KAT5 CREB3L3 CREB3L3 AKT3 AKT3 PRKACG PRKACG CCNE1 CCNE1 ADCY4 ADCY4 ETS1 ETS1 IL1R2 IL1R2 IL2 IL2 HRAS HRAS NFATC3 NFATC3 ESPL1 ESPL1 NFYB NFYB TBPL2 TBPL2 E2F1 E2F1 CDK4 CDK4 TGFB1 TGFB1 IKBKB IKBKB VAC14 VAC14 ITGAL ITGAL SRF SRF MAMU-DMA MAMU-DMA NFKB1 NFKB1 ANAPC4 ANAPC4 CDC16 CDC16 NRP1 NRP1 XPO1 XPO1 CHEK1 CHEK1 CHEK2 CHEK2 CREB1 CREB1 DLG1 DLG1 ANAPC5 ANAPC5 CREB3L4 CREB3L4 CDC20 CDC20 IKBKG IKBKG LOC114672301 LOC114672301 SMAD3 SMAD3 CREB5 CREB5 HLA-E HLA-E CDK2 CDK2 CCNA1 CCNA1 MAPK10 MAPK10 VDAC3 VDAC3 CCND3 CCND3 ZFP36 ZFP36 CHUK CHUK ADCY8 ADCY8 LCK LCK MAP2K4 MAP2K4 SMAD2 SMAD2 E2F3 E2F3 BUB1B BUB1B CALR CALR TBP TBP MAP3K3 MAP3K3 ATF2 ATF2 RB1 RB1 NFATC2 NFATC2 IL6 IL6 ADCY3 ADCY3 TLN2 TLN2 STAT5A STAT5A NRAS NRAS TNFRSF1A TNFRSF1A HLA-DRA HLA-DRA TGFBR1 TGFBR1 GPS2 GPS2 ADCY5 ADCY5 TRRAP TRRAP FOSL1 FOSL1 MAPK3 MAPK3 CD3G CD3G NFKBIA NFKBIA PRKACA PRKACA SLC2A1 SLC2A1 RELA RELA ATF6B ATF6B TNF TNF CCNB2 CCNB2 TLN1 TLN1 AKT2 AKT2 RANBP1 RANBP1 ADCY2 ADCY2 PRKACB PRKACB PIK3R3 PIK3R3 NFATC4 NFATC4 PPP3R1 PPP3R1 KAT2B KAT2B AKT1 AKT1 XIAP XIAP CD3E CD3E SLC25A6 SLC25A6 TCF3 TCF3 PTTG1 PTTG1 CREB3 CREB3 TNFRSF13C TNFRSF13C ADCY6 ADCY6 LOC720132 LOC720132 MAD1L1 MAD1L1 CREBBP CREBBP TSPO2 TSPO2 SLC25A31 SLC25A31 TBPL1 TBPL1 PIK3CD PIK3CD LOC710149 LOC710149 ADCY9 ADCY9 ATF4 ATF4 CD4 CD4 MAP2K2 MAP2K2 ADCY1 ADCY1 ANAPC1 ANAPC1 MAD2L1 MAD2L1 RAN RAN FOS FOS ANAPC7 ANAPC7 LOC114669810 LOC114669810 ITGB2 ITGB2 JUN JUN MAMU-DOA MAMU-DOA ADCY7 ADCY7 B2M B2M HLA-DRB5 HLA-DRB5 CDC26 CDC26 IL1R1 IL1R1 VDAC2 VDAC2 ENSMMUP00000076578 ENSMMUP00000076578 EP300 EP300 MSX1 MSX1 CDKN1A CDKN1A EGR1 EGR1 VDAC1 VDAC1 FDPS FDPS CCND1 CCND1 NFATC1 NFATC1 EGR2 EGR2 MAP3K1 MAP3K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN2BCyclin dependent kinase inhibitor 2B. (158 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (822 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
KRASKRAS proto-oncogene, GTPase. (412 aa)
NFKB2Nuclear factor kappa B subunit 2. (907 aa)
BUB3WD_REPEATS_REGION domain-containing protein. (369 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform 1. (278 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ELK4ETS domain-containing protein Elk-4 isoform a. (431 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
MSX2Msh homeobox 2. (265 aa)
CRTC2CREB-regulated transcription coactivator 2. (694 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
BCL2L1Bcl-2-like protein 1 isoform 1. (233 aa)
TSPOTranslocator protein isoform PBR. (169 aa)
CRTC1CREB-regulated transcription coactivator 1 isoform 3. (650 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
PTENUncharacterized protein. (589 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAMU-FMamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system. (348 aa)
LTALymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. (205 aa)
CRTC3CREB regulated transcription coactivator 3. (803 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ICAM1Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (543 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (432 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1130 aa)
JAK3Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (602 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
E2F2E2F transcription factor 2. (437 aa)
RANBP3Ran-binding protein 3 isoform RANBP3-a. (562 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CANXCalnexin. (592 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
RELBRELB proto-oncogene, NF-kB subunit. (574 aa)
PPP3CCSerine/threonine-protein phosphatase. (511 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
IL2RAInterleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (338 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 1. (520 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
CD3DIg_4 domain-containing protein. (171 aa)
IL2RGCytokine receptor common subunit gamma. (369 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
CDC27Cell division cycle protein 27 homolog isoform 1. (830 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
IL15Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (162 aa)
MAMU-DPAMHC class II antigen; Belongs to the MHC class II family. (260 aa)
ELK1ETS domain-containing protein Elk-1. (428 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (603 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
ETS1ETS proto-oncogene 1, transcription factor. (548 aa)
IL1R2Uncharacterized protein. (398 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
HRASTransforming protein p21. (189 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2120 aa)
NFYBCBFD_NFYB_HMF domain-containing protein. (208 aa)
TBPL2TATA-box binding protein like 2. (376 aa)
E2F1E2F transcription factor 1. (437 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa)
VAC14Tax1-binding protein 2. (782 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1169 aa)
SRFSerum response factor. (508 aa)
MAMU-DMAIg-like domain-containing protein. (276 aa)
NFKB1Uncharacterized protein. (977 aa)
ANAPC4Anaphase promoting complex subunit 4. (981 aa)
CDC16Cell division cycle protein 16 homolog. (620 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
XPO1Exportin-1. (1071 aa)
CHEK1STT3 oligosaccharyltransferase complex catalytic subunit A. (768 aa)
CHEK2Checkpoint kinase 2. (539 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform a. (755 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (489 aa)
LOC114672301ETS domain-containing protein. (488 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (357 aa)
CDK2Diacylglycerol kinase. (1053 aa)
CCNA1Cyclin-A1 isoform a; Belongs to the cyclin family. (465 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
VDAC3Uncharacterized protein. (299 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (315 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LCKTyrosine-protein kinase. (567 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
E2F3E2F transcription factor 3. (465 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1063 aa)
CALRCalreticulin. (417 aa)
TBPTATA-box binding protein. (326 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3 isoform 1. (657 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
RB1Retinoblastoma-associated protein. (928 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
TLN2Talin 2. (2547 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
HLA-DRAMamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (378 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
GPS2G protein pathway suppressor 2. (327 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CD3GCD3g molecule. (209 aa)
NFKBIANF-kappa-B inhibitor alpha. (317 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (669 aa)
RELARELA proto-oncogene, NF-kB subunit. (544 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
TLN1Talin 1. (2558 aa)
AKT2AKT serine/threonine kinase 2. (594 aa)
RANBP1RAN binding protein 1. (278 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
PIK3R3Uncharacterized protein. (507 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
PPP3R1Uncharacterized protein. (171 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
XIAPX-linked inhibitor of apoptosis. (535 aa)
CD3ECD3e molecule. (217 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (399 aa)
TCF3Transcription factor 3. (654 aa)
PTTG1Securin. (202 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (372 aa)
TNFRSF13CTNF receptor superfamily member 13C. (184 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
LOC720132Major histocompatibility complex, class I, AG; Belongs to the MHC class I family. (339 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
CREBBPCREB-binding protein isoform a. (2442 aa)
TSPO2Uncharacterized protein. (170 aa)
SLC25A31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC710149Ig-like domain-containing protein. (228 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
ATF4BZIP domain-containing protein. (351 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
ANAPC1Anaphase promoting complex subunit 1. (2016 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (280 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
LOC114669810Ig-like domain-containing protein; Belongs to the MHC class II family. (266 aa)
ITGB2Integrin beta. (911 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (334 aa)
MAMU-DOAIg-like domain-containing protein; Belongs to the MHC class II family. (342 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
HLA-DRB5Ig-like domain-containing protein. (287 aa)
CDC26Anaphase-promoting complex subunit CDC26. (85 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
ENSMMUP00000076578Ig-like domain-containing protein. (275 aa)
EP300Histone acetyltransferase p300. (2414 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (283 aa)
FDPSFarnesyl pyrophosphate synthase isoform a; Belongs to the FPP/GGPP synthase family. (419 aa)
CCND1Uncharacterized protein; Belongs to the cyclin family. (303 aa)
NFATC1Nuclear factor of activated T cells 1. (943 aa)
EGR2Uncharacterized protein. (489 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1508 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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