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| | HCK | Tyrosine-protein kinase. (504 aa) |
| | STAT2 | Signal transducer and activator of transcription. (851 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | IL6ST | Uncharacterized protein. (942 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (412 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (597 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | CCR3 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (355 aa) |
| | VEGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (489 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (884 aa) |
| | BID | BH3 interacting domain death agonist. (310 aa) |
| | IRF7 | Interferon regulatory factor 7. (504 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | LOC708622 | CD200 receptor 1 like. (275 aa) |
| | CXCL1 | C-X-C motif chemokine. (107 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | C3 | Uncharacterized protein. (1663 aa) |
| | MAMU-F | Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system. (348 aa) |
| | ICAM1 | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (543 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (513 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (511 aa) |
| | JAK2 | Tyrosine-protein kinase. (1137 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa) |
| | RPS27A-2 | Ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | UBA52 | Ubiquitin-60S ribosomal protein L40. (128 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (144 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | CALML5 | Calmodulin-like protein 5. (146 aa) |
| | CASP9 | Caspase-9 isoform alpha preproprotein; Belongs to the peptidase C14A family. (416 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (589 aa) |
| | RAC1 | Uncharacterized protein. (212 aa) |
| | HRAS | Transforming protein p21. (189 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | CCR4 | C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (632 aa) |
| | CCR8 | C-C chemokine receptor type 8; Receptor for the chemokines CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis (By similarity). (355 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (409 aa) |
| | LOC694631 | Uncharacterized protein. (190 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (711 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa) |
| | NFKB1 | Uncharacterized protein. (977 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. (716 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (489 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (357 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | LOC710751 | Uncharacterized protein. (189 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | STAT3 | Signal transducer and activator of transcription. (871 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (908 aa) |
| | UBC | Uncharacterized protein. (270 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | RB1 | Retinoblastoma-associated protein. (928 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | UBB | Uncharacterized protein. (229 aa) |
| | CD200R1 | Ig-like domain-containing protein. (349 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (554 aa) |
| | CD86 | CD86 molecule. (417 aa) |
| | LYN | Tyrosine-protein kinase. (577 aa) |
| | GABARAPL1 | Uncharacterized protein. (146 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CALML3 | Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (317 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (544 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (826 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | STAT1 | Signal transducer and activator of transcription. (802 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (594 aa) |
| | MAP2K6 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | LOC702827 | Uncharacterized protein. (117 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (961 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa) |
| | PPP3R1 | Uncharacterized protein. (171 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | LOC710568 | Interferon alpha 16. (189 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | LOC114675515 | Uncharacterized protein. (152 aa) |
| | LOC720132 | Major histocompatibility complex, class I, AG; Belongs to the MHC class I family. (339 aa) |
| | CREBBP | CREB-binding protein isoform a. (2442 aa) |
| | IRF9 | Interferon regulatory factor 9. (455 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa) |
| | TYK2 | Tyrosine-protein kinase. (1196 aa) |
| | IFNA6 | Interferon alpha-6. (189 aa) |
| | BAK1 | Uncharacterized protein. (261 aa) |
| | LOC703390 | C-X-C motif chemokine. (198 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | ATG3 | Autophagy-related protein 3. (314 aa) |
| | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa) |
| | FOS | V-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (308 aa) |
| | CCR1 | C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. (355 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | IFNA10 | Uncharacterized protein. (189 aa) |
| | CLEC2B | C-type lectin domain family 2 member B. (151 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (488 aa) |
| | IFNA8 | Interferon alpha-8. (189 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (334 aa) |
| | MIC1 | Ig-like domain-containing protein. (384 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa) |
| | CALM2 | Uncharacterized protein; Belongs to the calmodulin family. (204 aa) |
| | CXCL3 | C-X-C motif chemokine. (318 aa) |
| | EP300 | Histone acetyltransferase p300. (2414 aa) |
| | CALM3 | Calmodulin 3; Belongs to the calmodulin family. (194 aa) |
| | BECN2 | Beclin 2. (431 aa) |
| | IFNA13 | Uncharacterized protein. (190 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | IFNAR2 | Uncharacterized protein. (684 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa) |
| | CCND1 | Uncharacterized protein; Belongs to the cyclin family. (303 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (943 aa) |
