STRINGSTRING
SNRPD3 SNRPD3 LOC695427-2 LOC695427-2 LOC704994 LOC704994 H2BU1 H2BU1 H2AC20 H2AC20 H2AC21 H2AC21 HIST1H2BJ HIST1H2BJ CD40 CD40 CTSG CTSG H2AFY H2AFY C3 C3 H2AFB3 H2AFB3 ELANE ELANE SNRPB SNRPB H2BW2 H2BW2 ENSMMUP00000017083 ENSMMUP00000017083 LOC698767 LOC698767 LOC699443 LOC699443 H2AFJ H2AFJ GRIN2B GRIN2B MAMU-DPA MAMU-DPA C9 C9 C5 C5 C1QC C1QC C6 C6 HIST1H2BA HIST1H2BA C8A C8A IL10 IL10 HIST1H2AE HIST1H2AE LOC714001 LOC714001 MAMU-DMA MAMU-DMA HIST1H2AJ HIST1H2AJ HIST1H2AA HIST1H2AA H2BC18 H2BC18 FCGR1A FCGR1A LOC699317 LOC699317 C8G C8G CD40LG CD40LG H2BFWT H2BFWT C7 C7 LOC721200 LOC721200 H2AFX H2AFX LOC722133 LOC722133 ACTN1 ACTN1 GRIN2A GRIN2A H2AFZ H2AFZ LOC704664 LOC704664 HIST1H2AC HIST1H2AC FCGR3 FCGR3 LOC710748 LOC710748 HLA-DRA HLA-DRA CD86 CD86 HIST1H2BM HIST1H2BM ACTN4 ACTN4 H2BC5 H2BC5 LOC114669830 LOC114669830 TNF TNF H2BE1 H2BE1 HIST1H2BH HIST1H2BH LOC696506 LOC696506 C8B C8B IFNG IFNG H3-4 H3-4 CD28 CD28 SNRPD1 SNRPD1 LOC106999628 LOC106999628 LOC693939 LOC693939 LOC710149 LOC710149 LOC718280 LOC718280 RO60 RO60 H2AFY2 H2AFY2 LOC114669810 LOC114669810 MAMU-DOA MAMU-DOA CD80 CD80 HLA-DRB5 HLA-DRB5 C1QB C1QB C1S C1S TRIM21 TRIM21 ENSMMUP00000076578 ENSMMUP00000076578 HIST1H2BO HIST1H2BO FCGR2A FCGR2A HIST1H2BK HIST1H2BK H2AFV H2AFV H2BC15 H2BC15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD3Small nuclear ribonucleoprotein D3 polypeptide. (259 aa)
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
LOC704994Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
HIST1H2BJHistone H2B; Belongs to the histone H2B family. (126 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform 1. (278 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
H2AFYCore histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
C3Uncharacterized protein. (1663 aa)
H2AFB3Histone H2A; Belongs to the histone H2A family. (115 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
H2BW2H2B histone family member M; Belongs to the histone H2B family. (153 aa)
ENSMMUP00000017083Ig-like domain-containing protein. (183 aa)
LOC698767Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
LOC699443Histone H3; Belongs to the histone H3 family. (136 aa)
H2AFJHistone H2A; Belongs to the histone H2A family. (129 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
MAMU-DPAMHC class II antigen; Belongs to the MHC class II family. (260 aa)
C9Complement C9. (561 aa)
C5Complement C5. (1676 aa)
C1QCComplement C1q subcomponent subunit C. (245 aa)
C6Complement C6. (962 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (127 aa)
C8AComplement C8 alpha chain. (584 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
HIST1H2AEHistone H2A; Belongs to the histone H2A family. (130 aa)
LOC714001Histone H2B; Belongs to the histone H2B family. (126 aa)
MAMU-DMAIg-like domain-containing protein. (276 aa)
HIST1H2AJHistone H2A; Belongs to the histone H2A family. (128 aa)
HIST1H2AAHistone H2A; Belongs to the histone H2A family. (131 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (134 aa)
FCGR1AFCGRI variant 1. (357 aa)
LOC699317Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
H2BFWTHistone domain-containing protein; Belongs to the histone H2B family. (164 aa)
C7Complement C7. (855 aa)
LOC721200Uncharacterized protein. (1743 aa)
H2AFXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC722133Uncharacterized protein; Belongs to the peptidase S1 family. (750 aa)
ACTN1Actinin alpha 1. (914 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
LOC704664Histone H2A; Belongs to the histone H2A family. (130 aa)
HIST1H2ACHistone H2A; Belongs to the histone H2A family. (130 aa)
FCGR3Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Binds IgG1 and IgG2 (By similarity). (277 aa)
LOC710748Histone H3; Belongs to the histone H3 family. (136 aa)
HLA-DRAMamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (378 aa)
CD86CD86 molecule. (417 aa)
HIST1H2BMHistone H2B; Belongs to the histone H2B family. (126 aa)
ACTN4Actinin alpha 4. (911 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC114669830Histone H3; Belongs to the histone H3 family. (136 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
HIST1H2BHHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC696506Histone H2B; Belongs to the histone H2B family. (126 aa)
C8BComplement C8 beta chain. (591 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
CD28T-cell-specific surface glycoprotein CD28. (220 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (152 aa)
LOC106999628Ig-like domain-containing protein. (242 aa)
LOC693939Histone H3; Belongs to the histone H3 family. (136 aa)
LOC710149Ig-like domain-containing protein. (228 aa)
LOC718280Histone domain-containing protein. (136 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
H2AFY2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC114669810Ig-like domain-containing protein; Belongs to the MHC class II family. (266 aa)
MAMU-DOAIg-like domain-containing protein; Belongs to the MHC class II family. (342 aa)
CD80CD80 molecule. (288 aa)
HLA-DRB5Ig-like domain-containing protein. (287 aa)
C1QBComplement C1q subcomponent subunit B. (253 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (688 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21. (475 aa)
ENSMMUP00000076578Ig-like domain-containing protein. (275 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
FCGR2AUncharacterized protein. (316 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (138 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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