STRINGSTRING
LRIG1 LRIG1 LACRT LACRT TNF TNF ENSMNEP00000030245 ENSMNEP00000030245 EDA EDA CD1C CD1C TGFB1 TGFB1 ADIPOQ ADIPOQ ITGAX ITGAX DDC DDC CD207 CD207 IL6 IL6 PPARG PPARG KRT15 KRT15 LGR6 LGR6 KLF4 KLF4 COL1A2 COL1A2 FABP4 FABP4 UCP1 UCP1 MMP1 MMP1 LEP LEP LCN1 LCN1 CIDEA CIDEA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
LACRTLacritin. (137 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ENSMNEP00000030245Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (152 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
CD1CCD1c molecule. (332 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa)
DDCDopa decarboxylase. (480 aa)
CD207CD207 molecule. (328 aa)
IL6Interleukin 6. (214 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (456 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (920 aa)
KLF4Kruppel like factor 4. (479 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LCN1Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (176 aa)
CIDEACell death inducing DFFA like effector a. (196 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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