22 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRDM14	PR/SET domain 14. (571 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (357 aa)
	COL5A1	Collagen type V alpha 1 chain. (1840 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	ENSMNEP00000037489	Uncharacterized protein. (254 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
	NPM1	Nucleophosmin 1. (294 aa)
	GCM1	Glial cells missing transcription factor 1. (436 aa)
	LENG9	Leukocyte receptor cluster member 9. (437 aa)
	ENSMNEP00000024169	Nucleoplasmin domain-containing protein. (220 aa)
	ENSMNEP00000022200	Uncharacterized protein. (232 aa)
	ETV2	ETS variant 2. (376 aa)
	EVPL	Envoplakin. (2033 aa)
	ENSMNEP00000016207	Uncharacterized protein. (253 aa)
	ENSMNEP00000012292	Uncharacterized protein. (208 aa)
	ENSMNEP00000012230	Uncharacterized protein. (216 aa)
	DMD	Dystrophin. (3685 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	ENSMNEP00000004093	Uncharacterized protein. (305 aa)
	ENSMNEP00000003725	Nucleoplasmin domain-containing protein. (218 aa)
	PAPPA	Pappalysin 1. (1420 aa)
	IL6	Interleukin 6. (214 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	EVPL	ENSMNEP00000007383	ENSMNEP00000018544	Tyrosine-protein kinase.	Envoplakin.	0.575
EVPL	ABL1	ENSMNEP00000018544	ENSMNEP00000007383	Envoplakin.	Tyrosine-protein kinase.	0.575
FGF2	IL1B	ENSMNEP00000045834	ENSMNEP00000033521	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.560
FGF2	IL6	ENSMNEP00000045834	ENSMNEP00000000727	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Interleukin 6.	0.587
FGF2	KDR	ENSMNEP00000045834	ENSMNEP00000039919	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.896
IL1B	FGF2	ENSMNEP00000033521	ENSMNEP00000045834	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.560
IL1B	IL6	ENSMNEP00000033521	ENSMNEP00000000727	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 6.	0.932
IL6	FGF2	ENSMNEP00000000727	ENSMNEP00000045834	Interleukin 6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.587
IL6	IL1B	ENSMNEP00000000727	ENSMNEP00000033521	Interleukin 6.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.932
IL6	KDR	ENSMNEP00000000727	ENSMNEP00000039919	Interleukin 6.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.545
KDR	FGF2	ENSMNEP00000039919	ENSMNEP00000045834	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.896
KDR	IL6	ENSMNEP00000039919	ENSMNEP00000000727	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Interleukin 6.	0.545