STRINGSTRING
CXCL11 CXCL11 PRCC PRCC CEACAM1 CEACAM1 AHNAK AHNAK CD4 CD4 PPBP PPBP DYNC1H1 DYNC1H1 LTC4S LTC4S DUSP7 DUSP7 CCR2 CCR2 APOB APOB DCSTAMP DCSTAMP IFNAR2 IFNAR2 TLR4 TLR4 ITGAM ITGAM CLEC17A CLEC17A PDE4A PDE4A IL1B IL1B ENSMNEP00000033259 ENSMNEP00000033259 TOR2A TOR2A NFKBIA NFKBIA MYD88 MYD88 CLIP1 CLIP1 TNF TNF HHEX HHEX CLEC10A CLEC10A NFKBIZ NFKBIZ ENSMNEP00000023973 ENSMNEP00000023973 MACF1 MACF1 TFE3 TFE3 CCL23 CCL23 ATP10D ATP10D LITAF LITAF CTSG CTSG ENSMNEP00000019591 ENSMNEP00000019591 PTK2B PTK2B CCL17 CCL17 BANP BANP CXCR4 CXCR4 TNFSF13B TNFSF13B ARIH1 ARIH1 RC3H2 RC3H2 NEU1 NEU1 ADAM17 ADAM17 PTPRC PTPRC RUVBL1 RUVBL1 MARK3 MARK3 LOC105471157 LOC105471157 CD300E CD300E OASL OASL SERPINB2 SERPINB2 CCRL2 CCRL2 IRF8 IRF8 FBP1 FBP1 PARG PARG DDI1 DDI1 TNIP3 TNIP3 CCL24 CCL24 SIRPA SIRPA C1QC C1QC CYSLTR1 CYSLTR1 GPR171 GPR171 CD27 CD27 SIGLEC1 SIGLEC1 TLR2 TLR2 TREM1 TREM1 IL6 IL6 CXCL9 CXCL9 OAS3 OAS3 VSTM1 VSTM1 NFKBIL1 NFKBIL1 FCAR FCAR CD300LD CD300LD LY86 LY86 IFNG IFNG RUNX1 RUNX1 TXN TXN PIK3C2B PIK3C2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL11C-X-C motif chemokine. (96 aa)
PRCCProline rich mitotic checkpoint control factor. (491 aa)
CEACAM1Uncharacterized protein. (544 aa)
AHNAKPDZ domain-containing protein. (155 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
PPBPC-X-C motif chemokine. (128 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4586 aa)
LTC4SLeukotriene C4 synthase. (150 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
APOBApolipoprotein B. (4555 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
IFNAR2Uncharacterized protein. (516 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
CLEC17AC-type lectin domain containing 17A. (310 aa)
PDE4APhosphodiesterase 4A; Belongs to the cyclic nucleotide phosphodiesterase family. (852 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
ENSMNEP00000033259Uncharacterized protein. (1671 aa)
TOR2ATorsin. (321 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
CLEC10AC-type lectin domain containing 10A. (315 aa)
NFKBIZNFKB inhibitor zeta. (719 aa)
ENSMNEP00000023973Ig-like domain-containing protein. (543 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
CCL23C-C motif chemokine. (120 aa)
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1423 aa)
LITAFLipopolysaccharide induced TNF factor. (161 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
ENSMNEP00000019591Uncharacterized protein. (83 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
CCL17C-C motif chemokine. (91 aa)
BANPBTG3 associated nuclear protein. (538 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
ARIH1Ariadne RBR E3 ubiquitin protein ligase 1. (483 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
NEU1Neuraminidase 1. (416 aa)
ADAM17ADAM metallopeptidase domain 17. (803 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MARK3Non-specific serine/threonine protein kinase. (770 aa)
LOC105471157C-X-C motif chemokine. (103 aa)
CD300ECD300e molecule. (228 aa)
OASL2'-5'-oligoadenylate synthetase like. (515 aa)
SERPINB2Serpin family B member 2; Belongs to the serpin family. (415 aa)
CCRL2C-C motif chemokine receptor like 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)
IRF8Interferon regulatory factor 8. (434 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (341 aa)
PARGPoly(ADP-ribose) glycohydrolase. (976 aa)
DDI1DNA damage inducible 1 homolog 1. (396 aa)
TNIP3TNFAIP3 interacting protein 3. (402 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
SIRPAUncharacterized protein. (507 aa)
C1QCComplement C1q C chain. (245 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
GPR171G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. (319 aa)
CD27CD27 molecule. (260 aa)
SIGLEC1Sialic acid binding Ig like lectin 1. (1709 aa)
TLR2Toll-like receptor. (784 aa)
TREM1Triggering receptor expressed on myeloid cells 1. (248 aa)
IL6Interleukin 6. (214 aa)
CXCL9C-X-C motif chemokine ligand 9. (125 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1076 aa)
VSTM1V-set and transmembrane domain containing 1. (236 aa)
NFKBIL1NFKB inhibitor like 1. (403 aa)
FCARFc fragment of IgA receptor. (287 aa)
CD300LDCD300 molecule like family member d. (194 aa)
LY86Lymphocyte antigen 86. (162 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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