37 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	ADRB2	Adrenoceptor beta 2. (415 aa)
	IL5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
	ENSMNEP00000003725	Nucleoplasmin domain-containing protein. (218 aa)
	ENSMNEP00000004093	Uncharacterized protein. (305 aa)
	TPT1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (191 aa)
	IL13	Interleukin 13. (146 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	NCL	Nucleolin. (736 aa)
	HMGB1	High mobility group box 1. (215 aa)
	GADD45A	Growth arrest and DNA damage inducible alpha. (165 aa)
	ENSMNEP00000009545	TCTP domain-containing protein; Belongs to the TCTP family. (128 aa)
	ENSMNEP00000010344	Uncharacterized protein. (206 aa)
	ENSMNEP00000011718	Uncharacterized protein. (188 aa)
	ENSMNEP00000012230	Uncharacterized protein. (216 aa)
	ENSMNEP00000012292	Uncharacterized protein. (208 aa)
	SCGB1A1	Secretoglobin family 1A member 1. (91 aa)
	ENSMNEP00000013739	Uncharacterized protein. (202 aa)
	SFTPC	Surfactant protein C. (191 aa)
	ENSMNEP00000016207	Uncharacterized protein. (253 aa)
	SNTN	Sentan, cilia apical structure protein. (118 aa)
	SFTPD	Surfactant protein D. (375 aa)
	LOC105472153	Keratin 19; Belongs to the intermediate filament family. (340 aa)
	ENSMNEP00000020609	TCTP domain-containing protein; Belongs to the TCTP family. (170 aa)
	ENSMNEP00000022200	Uncharacterized protein. (232 aa)
	ANXA5	Annexin. (328 aa)
	ENSMNEP00000023431	IF rod domain-containing protein; Belongs to the intermediate filament family. (381 aa)
	ENSMNEP00000024169	Nucleoplasmin domain-containing protein. (220 aa)
	KRT5	Keratin 5; Belongs to the intermediate filament family. (597 aa)
	NPM1	Nucleophosmin 1. (294 aa)
	S100A2	Protein S100; Belongs to the S-100 family. (98 aa)
	RSPH1	Radial spoke head component 1. (343 aa)
	ENSMNEP00000037489	Uncharacterized protein. (254 aa)
	ENSMNEP00000041082	Uncharacterized protein; Belongs to the heat shock protein 70 family. (558 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	KRT14	Keratin 14; Belongs to the intermediate filament family. (475 aa)
	C9orf24	Chromosome 9 open reading frame 24. (262 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA5	IL1B	ENSMNEP00000023237	ENSMNEP00000033521	Annexin.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.410
ENSMNEP00000003725	NCL	ENSMNEP00000003725	ENSMNEP00000005239	Nucleoplasmin domain-containing protein.	Nucleolin.	0.812
ENSMNEP00000004093	NCL	ENSMNEP00000004093	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.781
ENSMNEP00000012230	NCL	ENSMNEP00000012230	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.812
ENSMNEP00000012292	NCL	ENSMNEP00000012292	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.781
ENSMNEP00000016207	NCL	ENSMNEP00000016207	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.812
ENSMNEP00000022200	NCL	ENSMNEP00000022200	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.781
ENSMNEP00000024169	NCL	ENSMNEP00000024169	ENSMNEP00000005239	Nucleoplasmin domain-containing protein.	Nucleolin.	0.781
ENSMNEP00000037489	NCL	ENSMNEP00000037489	ENSMNEP00000005239	Uncharacterized protein.	Nucleolin.	0.781
HIF1A	IL1B	ENSMNEP00000041174	ENSMNEP00000033521	Hypoxia inducible factor 1 subunit alpha.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.418
IL13	IL1B	ENSMNEP00000004502	ENSMNEP00000033521	Interleukin 13.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.769
IL13	IL5	ENSMNEP00000004502	ENSMNEP00000001992	Interleukin 13.	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	0.941
IL1B	ANXA5	ENSMNEP00000033521	ENSMNEP00000023237	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Annexin.	0.410
IL1B	HIF1A	ENSMNEP00000033521	ENSMNEP00000041174	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Hypoxia inducible factor 1 subunit alpha.	0.418
IL1B	IL13	ENSMNEP00000033521	ENSMNEP00000004502	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 13.	0.769
IL1B	IL5	ENSMNEP00000033521	ENSMNEP00000001992	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	0.788
IL5	IL13	ENSMNEP00000001992	ENSMNEP00000004502	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	Interleukin 13.	0.941
IL5	IL1B	ENSMNEP00000001992	ENSMNEP00000033521	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.788
KRT14	KRT5	ENSMNEP00000042473	ENSMNEP00000026118	Keratin 14; Belongs to the intermediate filament family.	Keratin 5; Belongs to the intermediate filament family.	0.989
KRT14	RSPH1	ENSMNEP00000042473	ENSMNEP00000036667	Keratin 14; Belongs to the intermediate filament family.	Radial spoke head component 1.	0.403