STRINGSTRING
NFKBIA NFKBIA TNF TNF PTGS2 PTGS2 TNFSF11 TNFSF11 ACP5 ACP5 IL6 IL6 TLR4 TLR4 IL1B IL1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFKBIANFKB inhibitor alpha. (317 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
IL6Interleukin 6. (214 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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