(38 nodes) Mixed, incl. Small GTPase, Ras-type, and Ras GTPase-activating protein network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RGL1	Ral guanine nucleotide dissociation stimulator like 1. (803 aa)
	RGL4	Ral guanine nucleotide dissociation stimulator like 4. (471 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	LOC105464688	Ras-GEF domain-containing protein. (387 aa)
	RASGRP2	RAS guanyl releasing protein 2. (771 aa)
	SPRED2	Sprouty related EVH1 domain containing 2. (432 aa)
	RASA1	RAS p21 protein activator 1. (1046 aa)
	RALA	RAS like proto-oncogene A. (206 aa)
	NF1	Neurofibromin 1. (2839 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	RRAS	RAS related. (218 aa)
	SIPA1	Signal-induced proliferation-associated 1. (1042 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (883 aa)
	RASGRP1	RAS guanyl releasing protein 1. (832 aa)
	RASGRP3	RAS guanyl releasing protein 3. (734 aa)
	RASAL2	RAS protein activator like 2. (1280 aa)
	RASA2	RAS p21 protein activator 2. (860 aa)
	RASGRP4	RAS guanyl releasing protein 4. (673 aa)
	LOC105492755	Uncharacterized protein. (905 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (444 aa)
	ENSMNEP00000025369	Uncharacterized protein. (129 aa)
	RALBP1	Rho-GAP domain-containing protein. (539 aa)
	ENSMNEP00000027485	Uncharacterized protein. (118 aa)
	SYNGAP1	Synaptic Ras GTPase activating protein 1. (1328 aa)
	RGL2	Ral guanine nucleotide dissociation stimulator like 2. (777 aa)
	SHOC2	SHOC2 leucine rich repeat scaffold protein. (582 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	RRAS2	RAS related 2. (204 aa)
	RAP1B	Uncharacterized protein. (137 aa)
	RASA3	RAS p21 protein activator 3. (834 aa)
	RAP1GAP	RAP1 GTPase activating protein. (750 aa)
	ENSMNEP00000039571	Uncharacterized protein. (136 aa)
	RALB	RAS like proto-oncogene B. (212 aa)
	RALGDS	Uncharacterized protein. (909 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSMNEP00000027485	ENSMNEP00000045466	ENSMNEP00000027485	Cold shock domain containing E1.	Uncharacterized protein.	0.531
CSDE1	NF1	ENSMNEP00000045466	ENSMNEP00000010411	Cold shock domain containing E1.	Neurofibromin 1.	0.784
CSDE1	NRAS	ENSMNEP00000045466	ENSMNEP00000044488	Cold shock domain containing E1.	NRAS proto-oncogene, GTPase.	0.410
CSDE1	RALBP1	ENSMNEP00000045466	ENSMNEP00000027195	Cold shock domain containing E1.	Rho-GAP domain-containing protein.	0.531
CSDE1	RALGDS	ENSMNEP00000045466	ENSMNEP00000044006	Cold shock domain containing E1.	Uncharacterized protein.	0.670
CSDE1	RAP1GAP	ENSMNEP00000045466	ENSMNEP00000037563	Cold shock domain containing E1.	RAP1 GTPase activating protein.	0.413
CSDE1	RAPGEF5	ENSMNEP00000045466	ENSMNEP00000018165	Cold shock domain containing E1.	Rap guanine nucleotide exchange factor 5.	0.533
CSDE1	RASA1	ENSMNEP00000045466	ENSMNEP00000008267	Cold shock domain containing E1.	RAS p21 protein activator 1.	0.773
CSDE1	RASA2	ENSMNEP00000045466	ENSMNEP00000021469	Cold shock domain containing E1.	RAS p21 protein activator 2.	0.583
CSDE1	RASA3	ENSMNEP00000045466	ENSMNEP00000037172	Cold shock domain containing E1.	RAS p21 protein activator 3.	0.469
CSDE1	RASGRP1	ENSMNEP00000045466	ENSMNEP00000018206	Cold shock domain containing E1.	RAS guanyl releasing protein 1.	0.581
CSDE1	RASGRP2	ENSMNEP00000045466	ENSMNEP00000005211	Cold shock domain containing E1.	RAS guanyl releasing protein 2.	0.559
CSDE1	RASGRP3	ENSMNEP00000045466	ENSMNEP00000020330	Cold shock domain containing E1.	RAS guanyl releasing protein 3.	0.444
CSDE1	RASGRP4	ENSMNEP00000045466	ENSMNEP00000022594	Cold shock domain containing E1.	RAS guanyl releasing protein 4.	0.558
CSDE1	RGL1	ENSMNEP00000045466	ENSMNEP00000000103	Cold shock domain containing E1.	Ral guanine nucleotide dissociation stimulator like 1.	0.741
CSDE1	RGL2	ENSMNEP00000045466	ENSMNEP00000031274	Cold shock domain containing E1.	Ral guanine nucleotide dissociation stimulator like 2.	0.727
CSDE1	SHOC2	ENSMNEP00000045466	ENSMNEP00000031725	Cold shock domain containing E1.	SHOC2 leucine rich repeat scaffold protein.	0.674
CSDE1	SPRED1	ENSMNEP00000045466	ENSMNEP00000024692	Cold shock domain containing E1.	Sprouty related EVH1 domain containing 1.	0.591
CSDE1	SPRED2	ENSMNEP00000045466	ENSMNEP00000007620	Cold shock domain containing E1.	Sprouty related EVH1 domain containing 2.	0.538
ENSMNEP00000025369	LOC105464688	ENSMNEP00000025369	ENSMNEP00000001063	Uncharacterized protein.	Ras-GEF domain-containing protein.	0.844