40 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG2B	Autophagy related 2B. (2078 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	SQSTM1	Sequestosome 1. (440 aa)
	NRBF2	Nuclear receptor binding factor 2. (287 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
	ATG13	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
	ATG16L1	Autophagy related 16 like 1. (624 aa)
	ENSMNEP00000012226	Uncharacterized protein. (104 aa)
	ULK2	Unc-51 like autophagy activating kinase 2. (1035 aa)
	BECN1	Beclin 1. (450 aa)
	LOC105476784	Uncharacterized protein. (147 aa)
	ATG14	Autophagy related 14. (493 aa)
	RB1CC1	RB1 inducible coiled-coil 1. (1594 aa)
	ENSMNEP00000015675	Uncharacterized protein. (105 aa)
	ENSMNEP00000016623	Uncharacterized protein. (111 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	PLEKHM1	Pleckstrin homology and RUN domain containing M1. (1055 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (125 aa)
	ULK1	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
	MAP1LC3B	Uncharacterized protein. (125 aa)
	WIPI2	WD repeat domain, phosphoinositide interacting 2. (451 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
	ATG16L2	Autophagy related 16 like 2. (696 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
	ATG4B	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (508 aa)
	ATG101	Autophagy related 101. (218 aa)
	ATG4C	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
	ULK3	Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
	ATG4A	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
	ATG2A	Autophagy related 2A. (1968 aa)
	FUNDC1	FUN14 domain containing 1. (155 aa)
	GABARAPL1	GABA type A receptor associated protein like 1. (146 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1298 aa)
	WIPI1	WD repeat domain, phosphoinositide interacting 1. (462 aa)
	NBR1	NBR1 autophagy cargo receptor. (960 aa)
	ATG3	Autophagy-related protein 3. (314 aa)
	ATG4D	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (447 aa)
	ENSMNEP00000043248	Uncharacterized protein. (82 aa)
	GABARAP	GABA type A receptor-associated protein. (117 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG101	ENSMNEP00000036577	ENSMNEP00000029648	Autophagy and beclin 1 regulator 1.	Autophagy related 101.	0.793
AMBRA1	ATG12	ENSMNEP00000036577	ENSMNEP00000018984	Autophagy and beclin 1 regulator 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.571
AMBRA1	ATG13	ENSMNEP00000036577	ENSMNEP00000008352	Autophagy and beclin 1 regulator 1.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.815
AMBRA1	ATG14	ENSMNEP00000036577	ENSMNEP00000014955	Autophagy and beclin 1 regulator 1.	Autophagy related 14.	0.975
AMBRA1	ATG16L1	ENSMNEP00000036577	ENSMNEP00000011457	Autophagy and beclin 1 regulator 1.	Autophagy related 16 like 1.	0.459
AMBRA1	ATG3	ENSMNEP00000036577	ENSMNEP00000040593	Autophagy and beclin 1 regulator 1.	Autophagy-related protein 3.	0.571
AMBRA1	ATG4A	ENSMNEP00000036577	ENSMNEP00000032816	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.533
AMBRA1	ATG4B	ENSMNEP00000036577	ENSMNEP00000029581	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.429
AMBRA1	ATG4C	ENSMNEP00000036577	ENSMNEP00000030425	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.502
AMBRA1	ATG4D	ENSMNEP00000036577	ENSMNEP00000042387	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.555
AMBRA1	ATG5	ENSMNEP00000036577	ENSMNEP00000017832	Autophagy and beclin 1 regulator 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.561
AMBRA1	ATG7	ENSMNEP00000036577	ENSMNEP00000007685	Autophagy and beclin 1 regulator 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.499
AMBRA1	BECN1	ENSMNEP00000036577	ENSMNEP00000014448	Autophagy and beclin 1 regulator 1.	Beclin 1.	0.981
AMBRA1	NRBF2	ENSMNEP00000036577	ENSMNEP00000005581	Autophagy and beclin 1 regulator 1.	Nuclear receptor binding factor 2.	0.939
AMBRA1	PIK3C3	ENSMNEP00000036577	ENSMNEP00000023886	Autophagy and beclin 1 regulator 1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.952
AMBRA1	PIK3R4	ENSMNEP00000036577	ENSMNEP00000028123	Autophagy and beclin 1 regulator 1.	Phosphoinositide-3-kinase regulatory subunit 4.	0.955
AMBRA1	RB1CC1	ENSMNEP00000036577	ENSMNEP00000015358	Autophagy and beclin 1 regulator 1.	RB1 inducible coiled-coil 1.	0.716
AMBRA1	ULK1	ENSMNEP00000036577	ENSMNEP00000021111	Autophagy and beclin 1 regulator 1.	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.	0.951
AMBRA1	ULK2	ENSMNEP00000036577	ENSMNEP00000013235	Autophagy and beclin 1 regulator 1.	Unc-51 like autophagy activating kinase 2.	0.938
ATG101	AMBRA1	ENSMNEP00000029648	ENSMNEP00000036577	Autophagy related 101.	Autophagy and beclin 1 regulator 1.	0.793