(12 nodes) Mixed, incl. Endopeptidase Clp complex, and Chaperonin Cpn60/GroEL network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMNEP00000001242	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	ENSMNEP00000001346	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (251 aa)
	LOC105484136	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	LOC105483144	10 kDa heat shock protein, mitochondrial. (102 aa)
	CLPX	Caseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
	ENSMNEP00000013195	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (520 aa)
	ENSMNEP00000022061	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (588 aa)
	YME1L1	YME1 like 1 ATPase. (735 aa)
	ENSMNEP00000036268	Uncharacterized protein. (256 aa)
	ENSMNEP00000037245	Uncharacterized protein. (56 aa)
	ENSMNEP00000039935	Uncharacterized protein; Belongs to the GrpE family. (216 aa)
	LONP1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPX	ENSMNEP00000037245	ENSMNEP00000011634	ENSMNEP00000037245	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Uncharacterized protein.	0.995
CLPX	LONP1	ENSMNEP00000011634	ENSMNEP00000040040	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]	0.666
CLPX	YME1L1	ENSMNEP00000011634	ENSMNEP00000031738	Caseinolytic mitochondrial matrix peptidase chaperone subunit.	YME1 like 1 ATPase.	0.808
ENSMNEP00000001242	ENSMNEP00000001346	ENSMNEP00000001242	ENSMNEP00000001346	Uncharacterized protein; Belongs to the GroES chaperonin family.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.809
ENSMNEP00000001242	ENSMNEP00000013195	ENSMNEP00000001242	ENSMNEP00000013195	Uncharacterized protein; Belongs to the GroES chaperonin family.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.805
ENSMNEP00000001242	ENSMNEP00000022061	ENSMNEP00000001242	ENSMNEP00000022061	Uncharacterized protein; Belongs to the GroES chaperonin family.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.805
ENSMNEP00000001242	ENSMNEP00000037245	ENSMNEP00000001242	ENSMNEP00000037245	Uncharacterized protein; Belongs to the GroES chaperonin family.	Uncharacterized protein.	0.602
ENSMNEP00000001242	ENSMNEP00000039935	ENSMNEP00000001242	ENSMNEP00000039935	Uncharacterized protein; Belongs to the GroES chaperonin family.	Uncharacterized protein; Belongs to the GrpE family.	0.761
ENSMNEP00000001242	LONP1	ENSMNEP00000001242	ENSMNEP00000040040	Uncharacterized protein; Belongs to the GroES chaperonin family.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]	0.432
ENSMNEP00000001346	ENSMNEP00000001242	ENSMNEP00000001346	ENSMNEP00000001242	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.809
ENSMNEP00000001346	ENSMNEP00000037245	ENSMNEP00000001346	ENSMNEP00000037245	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein.	0.518
ENSMNEP00000001346	ENSMNEP00000039935	ENSMNEP00000001346	ENSMNEP00000039935	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GrpE family.	0.652
ENSMNEP00000001346	LOC105483144	ENSMNEP00000001346	ENSMNEP00000003270	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	10 kDa heat shock protein, mitochondrial.	0.814
ENSMNEP00000001346	LOC105484136	ENSMNEP00000001346	ENSMNEP00000001738	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.814
ENSMNEP00000001346	LONP1	ENSMNEP00000001346	ENSMNEP00000040040	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]	0.531
ENSMNEP00000013195	ENSMNEP00000001242	ENSMNEP00000013195	ENSMNEP00000001242	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.805
ENSMNEP00000013195	ENSMNEP00000037245	ENSMNEP00000013195	ENSMNEP00000037245	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein.	0.518
ENSMNEP00000013195	ENSMNEP00000039935	ENSMNEP00000013195	ENSMNEP00000039935	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GrpE family.	0.652
ENSMNEP00000013195	LOC105483144	ENSMNEP00000013195	ENSMNEP00000003270	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	10 kDa heat shock protein, mitochondrial.	0.810
ENSMNEP00000013195	LOC105484136	ENSMNEP00000013195	ENSMNEP00000001738	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.810