(27 nodes) Chaperonin-containing T-complex, and Prefoldin complex network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCT6A	Uncharacterized protein. (391 aa)
	ENSMNEP00000002554	Uncharacterized protein. (530 aa)
	VBP1	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
	ENSMNEP00000005495	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (77 aa)
	CCT3	T-complex protein 1 subunit gamma. (545 aa)
	PFDN4	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
	ENSMNEP00000007348	Uncharacterized protein. (318 aa)
	PFDN6	Prefoldin subunit 6. (129 aa)
	ENSMNEP00000017255	Uncharacterized protein. (152 aa)
	CCT8	Chaperonin containing TCP1 subunit 8. (553 aa)
	CCT2	Chaperonin containing TCP1 subunit 2. (535 aa)
	ENSMNEP00000020011	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (474 aa)
	ENSMNEP00000020415	Uncharacterized protein. (382 aa)
	ENSMNEP00000020570	Uncharacterized protein. (366 aa)
	ERMARD	ER membrane associated RNA degradation. (764 aa)
	ENSMNEP00000027869	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (146 aa)
	CCT5	Chaperonin containing TCP1 subunit 5. (541 aa)
	PFDN2	Prefoldin subunit 2. (154 aa)
	PFDN1	Prefoldin subunit 1. (122 aa)
	PFDN5	Uncharacterized protein. (160 aa)
	ENSMNEP00000030430	Uncharacterized protein. (474 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	CCT7	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (639 aa)
	BBS10	Bardet-Biedl syndrome 10. (720 aa)
	TCP1	Uncharacterized protein. (556 aa)
	CCT6B	Chaperonin containing TCP1 subunit 6B. (535 aa)
	CCT4	T-complex protein 1 subunit delta. (552 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS10	CCT2	ENSMNEP00000034002	ENSMNEP00000018990	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 2.	0.980
BBS10	CCT3	ENSMNEP00000034002	ENSMNEP00000006436	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit gamma.	0.950
BBS10	CCT4	ENSMNEP00000034002	ENSMNEP00000043452	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit delta.	0.977
BBS10	CCT5	ENSMNEP00000034002	ENSMNEP00000029109	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 5.	0.943
BBS10	CCT6A	ENSMNEP00000034002	ENSMNEP00000000887	Bardet-Biedl syndrome 10.	Uncharacterized protein.	0.871
BBS10	CCT6B	ENSMNEP00000034002	ENSMNEP00000036987	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 6B.	0.871
BBS10	CCT7	ENSMNEP00000034002	ENSMNEP00000033952	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.943
BBS10	CCT8	ENSMNEP00000034002	ENSMNEP00000018042	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 8.	0.986
BBS10	ENSMNEP00000002554	ENSMNEP00000034002	ENSMNEP00000002554	Bardet-Biedl syndrome 10.	Uncharacterized protein.	0.871
BBS10	ENSMNEP00000005495	ENSMNEP00000034002	ENSMNEP00000005495	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.943
BBS10	ENSMNEP00000007348	ENSMNEP00000034002	ENSMNEP00000007348	Bardet-Biedl syndrome 10.	Uncharacterized protein.	0.871
BBS10	ENSMNEP00000017255	ENSMNEP00000034002	ENSMNEP00000017255	Bardet-Biedl syndrome 10.	Uncharacterized protein.	0.433
BBS10	ENSMNEP00000020011	ENSMNEP00000034002	ENSMNEP00000020011	Bardet-Biedl syndrome 10.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.871
BBS10	ENSMNEP00000027869	ENSMNEP00000034002	ENSMNEP00000027869	Bardet-Biedl syndrome 10.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.943
BBS10	ERMARD	ENSMNEP00000034002	ENSMNEP00000022402	Bardet-Biedl syndrome 10.	ER membrane associated RNA degradation.	0.935
BBS10	MKKS	ENSMNEP00000034002	ENSMNEP00000032600	Bardet-Biedl syndrome 10.	McKusick-Kaufman syndrome.	0.660
BBS10	PFDN1	ENSMNEP00000034002	ENSMNEP00000030120	Bardet-Biedl syndrome 10.	Prefoldin subunit 1.	0.519
BBS10	PFDN2	ENSMNEP00000034002	ENSMNEP00000029377	Bardet-Biedl syndrome 10.	Prefoldin subunit 2.	0.412
BBS10	PFDN4	ENSMNEP00000034002	ENSMNEP00000007042	Bardet-Biedl syndrome 10.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.614
BBS10	PFDN5	ENSMNEP00000034002	ENSMNEP00000030243	Bardet-Biedl syndrome 10.	Uncharacterized protein.	0.433