(18 nodes) Sin3 complex, and Sds3-like network (Macaca nemestrina)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMNEP00000002766	Uncharacterized protein. (266 aa)
	ARID4B	AT-rich interaction domain 4B. (1313 aa)
	SIN3B	SIN3 transcription regulator family member B. (1159 aa)
	ENSMNEP00000016650	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa)
	HDAC8	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
	SIN3A	SIN3 transcription regulator family member A. (1273 aa)
	SAP30L	SAP30 like. (184 aa)
	ENSMNEP00000024141	Uncharacterized protein. (106 aa)
	BRMS1	BRMS1 transcriptional repressor and anoikis regulator. (246 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (483 aa)
	ARID4A	AT-rich interaction domain 4A. (1262 aa)
	SAP130	Sin3A associated protein 130. (1083 aa)
	SUDS3	SDS3 homolog, SIN3A corepressor complex component. (328 aa)
	SAP30	Sin3A associated protein 30. (220 aa)
	ING1	Inhibitor of growth protein. (419 aa)
	SINHCAF	Uncharacterized protein. (221 aa)
	BRMS1L	BRMS1 like transcriptional repressor. (323 aa)
	ING2	Inhibitor of growth protein. (280 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ARID4B	ENSMNEP00000028380	ENSMNEP00000003255	AT-rich interaction domain 4A.	AT-rich interaction domain 4B.	0.643
ARID4A	BRMS1	ENSMNEP00000028380	ENSMNEP00000026259	AT-rich interaction domain 4A.	BRMS1 transcriptional repressor and anoikis regulator.	0.985
ARID4A	BRMS1L	ENSMNEP00000028380	ENSMNEP00000042130	AT-rich interaction domain 4A.	BRMS1 like transcriptional repressor.	0.983
ARID4A	ENSMNEP00000002766	ENSMNEP00000028380	ENSMNEP00000002766	AT-rich interaction domain 4A.	Uncharacterized protein.	0.983
ARID4A	ENSMNEP00000016650	ENSMNEP00000028380	ENSMNEP00000016650	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.943
ARID4A	ENSMNEP00000024141	ENSMNEP00000028380	ENSMNEP00000024141	AT-rich interaction domain 4A.	Uncharacterized protein.	0.981
ARID4A	HDAC1	ENSMNEP00000028380	ENSMNEP00000027311	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.943
ARID4A	HDAC8	ENSMNEP00000028380	ENSMNEP00000019671	AT-rich interaction domain 4A.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.943
ARID4A	ING1	ENSMNEP00000028380	ENSMNEP00000033441	AT-rich interaction domain 4A.	Inhibitor of growth protein.	0.766
ARID4A	ING2	ENSMNEP00000028380	ENSMNEP00000046197	AT-rich interaction domain 4A.	Inhibitor of growth protein.	0.766
ARID4A	SAP30	ENSMNEP00000028380	ENSMNEP00000032972	AT-rich interaction domain 4A.	Sin3A associated protein 30.	0.981
ARID4A	SAP30L	ENSMNEP00000028380	ENSMNEP00000024102	AT-rich interaction domain 4A.	SAP30 like.	0.981
ARID4A	SIN3A	ENSMNEP00000028380	ENSMNEP00000023540	AT-rich interaction domain 4A.	SIN3 transcription regulator family member A.	0.941
ARID4A	SIN3B	ENSMNEP00000028380	ENSMNEP00000014750	AT-rich interaction domain 4A.	SIN3 transcription regulator family member B.	0.941
ARID4A	SINHCAF	ENSMNEP00000028380	ENSMNEP00000039718	AT-rich interaction domain 4A.	Uncharacterized protein.	0.779
ARID4A	SUDS3	ENSMNEP00000028380	ENSMNEP00000031464	AT-rich interaction domain 4A.	SDS3 homolog, SIN3A corepressor complex component.	0.983
ARID4B	ARID4A	ENSMNEP00000003255	ENSMNEP00000028380	AT-rich interaction domain 4B.	AT-rich interaction domain 4A.	0.643
ARID4B	BRMS1	ENSMNEP00000003255	ENSMNEP00000026259	AT-rich interaction domain 4B.	BRMS1 transcriptional repressor and anoikis regulator.	0.984
ARID4B	BRMS1L	ENSMNEP00000003255	ENSMNEP00000042130	AT-rich interaction domain 4B.	BRMS1 like transcriptional repressor.	0.986
ARID4B	ENSMNEP00000002766	ENSMNEP00000003255	ENSMNEP00000002766	AT-rich interaction domain 4B.	Uncharacterized protein.	0.986