STRINGSTRING
HEXIM1 HEXIM1 SOWAHB SOWAHB NR2F2 NR2F2 AKT1 AKT1 RGCC RGCC GTF2H1 GTF2H1 CDC37 CDC37 HHEX HHEX SPDYE4 SPDYE4 CCND3 CCND3 CDC25A CDC25A CCNY CCNY PDGFB PDGFB LOC105476830 LOC105476830 CDKN3 CDKN3 CDK5RAP1 CDK5RAP1 MYOCD MYOCD CKS1B CKS1B PKMYT1 PKMYT1 CDKN2A CDKN2A ENSMNEP00000044053 ENSMNEP00000044053 CCNF CCNF GTPBP4 GTPBP4 ENSMNEP00000043093 ENSMNEP00000043093 PLK1 PLK1 APC APC PSMD10 PSMD10 PKD1 PKD1 CCNL1 CCNL1 CCNT2 CCNT2 ENSMNEP00000039425 ENSMNEP00000039425 LATS1 LATS1 CCNT1 CCNT1 ENSMNEP00000038942 ENSMNEP00000038942 CCNK CCNK CCNI2 CCNI2 ENSMNEP00000036332 ENSMNEP00000036332 CDKN2B CDKN2B CNPPD1 CNPPD1 CCND1 CCND1 ENSMNEP00000034956 ENSMNEP00000034956 HERC5 HERC5 IPO5 IPO5 ENSMNEP00000020148 ENSMNEP00000020148 MEN1 MEN1 CDKN2D CDKN2D SPDYC SPDYC BCCIP BCCIP WEE2 WEE2 HEXIM2 HEXIM2 CCNE2 CCNE2 PIM1 PIM1 CKS2 CKS2 CDKN2C CDKN2C CDKN1B CDKN1B ENSMNEP00000031812 ENSMNEP00000031812 SPDYA SPDYA CCNG2 CCNG2 ENSMNEP00000032887 ENSMNEP00000032887 ENSMNEP00000014340 ENSMNEP00000014340 PROX1 PROX1 CCNO CCNO CCND2 CCND2 CDK7 CDK7 SRC SRC SFN SFN CNTD2 CNTD2 CCNE1 CCNE1 KAT2B KAT2B PTEN PTEN FBXO7 FBXO7 CCNI CCNI CDK5R1 CDK5R1 EGFR EGFR CCNJL CCNJL ENSMNEP00000008233 ENSMNEP00000008233 CCNA1 CCNA1 PSRC1 PSRC1 ENSMNEP00000008717 ENSMNEP00000008717 GADD45A GADD45A PKD2 PKD2 ENSMNEP00000012244 ENSMNEP00000012244 TFAP4 TFAP4 ENSMNEP00000012932 ENSMNEP00000012932 ADAM17 ADAM17 INCA1 INCA1 BLM BLM LOC105499837 LOC105499837 CDC6 CDC6 CDK5R2 CDK5R2 CCNA2 CCNA2 SERTAD1 SERTAD1 MNAT1 MNAT1 CCNYL1 CCNYL1 CDKN1A CDKN1A ENSMNEP00000023008 ENSMNEP00000023008 CCNB3 CCNB3 CCNJ CCNJ IPO7 IPO7 ENSMNEP00000000865 ENSMNEP00000000865 MAPRE3 MAPRE3 CCNB1 CCNB1 LATS2 LATS2 CDC25C CDC25C TNFAIP3 TNFAIP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
SOWAHBSosondowah ankyrin repeat domain family member B. (793 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RGCCRegulator of cell cycle. (137 aa)
GTF2H1General transcription factor IIH subunit 1. (562 aa)
CDC37Cell division cycle 37. (378 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
SPDYE4Speedy/RINGO cell cycle regulator family member E4. (237 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (242 aa)
CDC25ACell division cycle 25A. (524 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC105476830Uncharacterized protein. (295 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)
CDK5RAP1CDK5 regulatory subunit associated protein 1. (587 aa)
MYOCDMyocardin. (986 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
PKMYT1Protein kinase, membrane associated tyrosine/threonine 1. (555 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (160 aa)
ENSMNEP00000044053CYCLIN domain-containing protein; Belongs to the cyclin family. (329 aa)
CCNFCyclin F; Belongs to the cyclin family. (874 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
ENSMNEP00000043093CYCLIN domain-containing protein; Belongs to the cyclin family. (393 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
APCAPC regulator of WNT signaling pathway. (2864 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (526 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (760 aa)
ENSMNEP00000039425Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
LATS1Large tumor suppressor kinase 1. (1129 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
ENSMNEP00000038942Uncharacterized protein. (476 aa)
CCNKCyclin K; Belongs to the cyclin family. (571 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (384 aa)
ENSMNEP00000036332Uncharacterized protein. (348 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
CNPPD1Cyclin Pas1/PHO80 domain containing 1. (410 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ENSMNEP00000034956Uncharacterized protein. (314 aa)
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (947 aa)
IPO5Importin 5. (1115 aa)
ENSMNEP00000020148BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (274 aa)
MEN1Menin 1. (610 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
SPDYCSpeedy/RINGO cell cycle regulator family member C. (293 aa)
BCCIPBRCA2 and CDKN1A interacting protein. (323 aa)
WEE2Wee1-like protein kinase. (568 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (339 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
PIM1Pim-1 proto-oncogene, serine/threonine kinase. (529 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ENSMNEP00000031812Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (94 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (313 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
ENSMNEP00000032887Protein kinase domain-containing protein. (324 aa)
ENSMNEP00000014340Uncharacterized protein. (206 aa)
PROX1Prospero homeobox 1. (737 aa)
CCNOCyclin O; Belongs to the cyclin family. (350 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
SRCTyrosine-protein kinase. (644 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (800 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
FBXO7F-box protein 7. (522 aa)
CCNICYCLIN domain-containing protein; Belongs to the cyclin family. (377 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (436 aa)
ENSMNEP00000008233Uncharacterized protein. (855 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PSRC1Proline and serine rich coiled-coil 1. (385 aa)
ENSMNEP00000008717Cyclin N-terminal domain-containing protein. (304 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
ENSMNEP00000012244Uncharacterized protein. (216 aa)
TFAP4Transcription factor AP-4. (338 aa)
ENSMNEP00000012932Uncharacterized protein. (343 aa)
ADAM17ADAM metallopeptidase domain 17. (803 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (236 aa)
BLMBLM RecQ like helicase. (1375 aa)
LOC105499837CYCLIN domain-containing protein. (360 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (544 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
SERTAD1SERTA domain containing 1. (236 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (316 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1363 aa)
CCNJCyclin J; Belongs to the cyclin family. (431 aa)
IPO7Importin 7. (1038 aa)
ENSMNEP00000000865Uncharacterized protein. (124 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
CDC25CCell division cycle 25C. (507 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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