52 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PHB2	Prohibitin. (299 aa)
	ATG2B	Autophagy related 2B. (2078 aa)
	C5orf51	Chromosome 5 open reading frame 51. (332 aa)
	FUNDC2	FUN14 domain containing 2. (189 aa)
	ENSMNEP00000003819	Uncharacterized protein. (322 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	LRBA	LPS responsive beige-like anchor protein. (2852 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	BNIP3	BCL2 interacting protein 3. (253 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	FBXO7	F-box protein 7. (522 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (270 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
	ENSMNEP00000012226	Uncharacterized protein. (104 aa)
	ULK2	Unc-51 like autophagy activating kinase 2. (1035 aa)
	LOC105476784	Uncharacterized protein. (147 aa)
	ATG14	Autophagy related 14. (493 aa)
	RB1CC1	RB1 inducible coiled-coil 1. (1594 aa)
	ENSMNEP00000016623	Uncharacterized protein. (111 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	SNX30	Sorting nexin family member 30. (437 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ENSMNEP00000018005	Uncharacterized protein. (133 aa)
	ENSMNEP00000018092	Prohibitin. (270 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (125 aa)
	SPATA18	Spermatogenesis associated 18. (538 aa)
	FBXL4	F-box and leucine rich repeat protein 4. (621 aa)
	ULK1	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
	ENSMNEP00000021271	Prohibitin. (286 aa)
	PRAF2	Uncharacterized protein. (361 aa)
	MAP1LC3B	Uncharacterized protein. (125 aa)
	WIPI2	WD repeat domain, phosphoinositide interacting 2. (451 aa)
	SPATA33	Spermatogenesis associated 33. (140 aa)
	ATG9B	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
	ATG4B	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (508 aa)
	SLC25A46	Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
	TAZ	Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa)
	ATG2A	Autophagy related 2A. (1968 aa)
	FUNDC1	FUN14 domain containing 1. (155 aa)
	ENSMNEP00000035659	Prohibitin. (112 aa)
	CISD2	CDGSH iron sulfur domain 2. (142 aa)
	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1298 aa)
	RETREG1	Reticulophagy regulator 1. (497 aa)
	ENSMNEP00000038142	Uncharacterized protein. (194 aa)
	WIPI1	WD repeat domain, phosphoinositide interacting 1. (462 aa)
	ARFIP2	ADP ribosylation factor interacting protein 2. (341 aa)
	ATG3	Autophagy-related protein 3. (314 aa)
	USP30	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
	ATG4D	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (447 aa)
	ENSMNEP00000043248	Uncharacterized protein. (82 aa)
	MARK2	Non-specific serine/threonine protein kinase. (788 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG14	ENSMNEP00000036577	ENSMNEP00000014955	Autophagy and beclin 1 regulator 1.	Autophagy related 14.	0.975
AMBRA1	ATG3	ENSMNEP00000036577	ENSMNEP00000040593	Autophagy and beclin 1 regulator 1.	Autophagy-related protein 3.	0.571
AMBRA1	ATG4B	ENSMNEP00000036577	ENSMNEP00000029581	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.429
AMBRA1	ATG4D	ENSMNEP00000036577	ENSMNEP00000042387	Autophagy and beclin 1 regulator 1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.555
AMBRA1	ATG5	ENSMNEP00000036577	ENSMNEP00000017832	Autophagy and beclin 1 regulator 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.561
AMBRA1	ATG7	ENSMNEP00000036577	ENSMNEP00000007685	Autophagy and beclin 1 regulator 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.499
AMBRA1	BNIP3	ENSMNEP00000036577	ENSMNEP00000006494	Autophagy and beclin 1 regulator 1.	BCL2 interacting protein 3.	0.479
AMBRA1	PRKN	ENSMNEP00000036577	ENSMNEP00000006722	Autophagy and beclin 1 regulator 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.943
AMBRA1	RB1CC1	ENSMNEP00000036577	ENSMNEP00000015358	Autophagy and beclin 1 regulator 1.	RB1 inducible coiled-coil 1.	0.716
AMBRA1	ULK1	ENSMNEP00000036577	ENSMNEP00000021111	Autophagy and beclin 1 regulator 1.	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.	0.951
AMBRA1	ULK2	ENSMNEP00000036577	ENSMNEP00000013235	Autophagy and beclin 1 regulator 1.	Unc-51 like autophagy activating kinase 2.	0.938
ATG14	AMBRA1	ENSMNEP00000014955	ENSMNEP00000036577	Autophagy related 14.	Autophagy and beclin 1 regulator 1.	0.975
ATG14	ATG2A	ENSMNEP00000014955	ENSMNEP00000032894	Autophagy related 14.	Autophagy related 2A.	0.437
ATG14	ATG2B	ENSMNEP00000014955	ENSMNEP00000002607	Autophagy related 14.	Autophagy related 2B.	0.437
ATG14	ATG3	ENSMNEP00000014955	ENSMNEP00000040593	Autophagy related 14.	Autophagy-related protein 3.	0.602
ATG14	ATG4B	ENSMNEP00000014955	ENSMNEP00000029581	Autophagy related 14.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.555
ATG14	ATG4D	ENSMNEP00000014955	ENSMNEP00000042387	Autophagy related 14.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.436
ATG14	ATG5	ENSMNEP00000014955	ENSMNEP00000017832	Autophagy related 14.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.867
ATG14	ATG7	ENSMNEP00000014955	ENSMNEP00000007685	Autophagy related 14.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.556
ATG14	ATG9B	ENSMNEP00000014955	ENSMNEP00000027518	Autophagy related 14.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.696