20 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IFNGR1	Interferon gamma receptor 1. (488 aa)
	CLU	Clusterin. (534 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
	APP	Amyloid beta precursor protein. (770 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	AGER	Advanced glycosylation end-product specific receptor. (414 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (407 aa)
	AZU1	Azurocidin 1. (250 aa)
	ITGB2	Integrin beta. (921 aa)
	GRN	Granulin precursor. (634 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
	IFNGR2	Interferon gamma receptor 2. (312 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	JAK2	Tyrosine-protein kinase. (1139 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	C5AR1	Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
	IL33	Interleukin 33. (270 aa)
	TYROBP	TYRO protein tyrosine kinase binding protein. (144 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	APP	ENSMNEP00000018479	ENSMNEP00000045820	Advanced glycosylation end-product specific receptor.	Amyloid beta precursor protein.	0.650
AGER	JAK2	ENSMNEP00000018479	ENSMNEP00000014154	Advanced glycosylation end-product specific receptor.	Tyrosine-protein kinase.	0.918
APP	AGER	ENSMNEP00000045820	ENSMNEP00000018479	Amyloid beta precursor protein.	Advanced glycosylation end-product specific receptor.	0.650
APP	CLU	ENSMNEP00000045820	ENSMNEP00000040244	Amyloid beta precursor protein.	Clusterin.	0.904
APP	TNF	ENSMNEP00000045820	ENSMNEP00000029202	Amyloid beta precursor protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.406
APP	TREM2	ENSMNEP00000045820	ENSMNEP00000026141	Amyloid beta precursor protein.	Triggering receptor expressed on myeloid cells 2.	0.583
CLU	APP	ENSMNEP00000040244	ENSMNEP00000045820	Clusterin.	Amyloid beta precursor protein.	0.904
CLU	TREM2	ENSMNEP00000040244	ENSMNEP00000026141	Clusterin.	Triggering receptor expressed on myeloid cells 2.	0.576
CX3CL1	CX3CR1	ENSMNEP00000018858	ENSMNEP00000014456	C-X3-C motif chemokine ligand 1.	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.999
CX3CL1	IFNG	ENSMNEP00000018858	ENSMNEP00000045088	C-X3-C motif chemokine ligand 1.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.507
CX3CR1	CX3CL1	ENSMNEP00000014456	ENSMNEP00000018858	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	C-X3-C motif chemokine ligand 1.	0.999
CX3CR1	IFNG	ENSMNEP00000014456	ENSMNEP00000045088	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.582
CX3CR1	ITGAM	ENSMNEP00000014456	ENSMNEP00000034715	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.406
CX3CR1	JAK2	ENSMNEP00000014456	ENSMNEP00000014154	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Tyrosine-protein kinase.	0.855
CX3CR1	TNF	ENSMNEP00000014456	ENSMNEP00000029202	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.534
CX3CR1	TREM2	ENSMNEP00000014456	ENSMNEP00000026141	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Triggering receptor expressed on myeloid cells 2.	0.574
CX3CR1	TYROBP	ENSMNEP00000014456	ENSMNEP00000038088	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	TYRO protein tyrosine kinase binding protein.	0.547
IFNG	CX3CL1	ENSMNEP00000045088	ENSMNEP00000018858	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	C-X3-C motif chemokine ligand 1.	0.507
IFNG	CX3CR1	ENSMNEP00000045088	ENSMNEP00000014456	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.582
IFNG	IFNGR1	ENSMNEP00000045088	ENSMNEP00000039279	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interferon gamma receptor 1.	0.999