STRINGSTRING
HAS2 HAS2 NOTCH1 NOTCH1 LOXL3 LOXL3 PDCD6 PDCD6 SMAD4 SMAD4 OLFM1 OLFM1 RFLNB RFLNB EPB41L5 EPB41L5 TGFBR1 TGFBR1 MSX1 MSX1 NOLC1 NOLC1 EOMES EOMES FGFR1 FGFR1 HEY1 HEY1 FAM83D FAM83D SNAI2 SNAI2 ADAM15 ADAM15 LRP6 LRP6 RTN4 RTN4 WNT4 WNT4 EDN1 EDN1 GSK3B GSK3B DLG5 DLG5 DDX17 DDX17 WNT5A WNT5A TMEM100 TMEM100 SPRY1 SPRY1 FOXF2 FOXF2 HEYL HEYL TBX3 TBX3 BMP7 BMP7 DACT3 DACT3 CTNNB1 CTNNB1 EDNRA EDNRA TGFBR3L TGFBR3L AKNA AKNA WNT8A WNT8A ENG ENG TGFBR3 TGFBR3 HMGA2 HMGA2 GSC GSC TASOR TASOR S100A4 S100A4 WNT2 WNT2 POLR1B POLR1B EFNA1 EFNA1 TRIM28 TRIM28 BMP2 BMP2 SNAI1 SNAI1 SFRP1 SFRP1 HEY2 HEY2 WNT16 WNT16 ROCK1 ROCK1 TCOF1 TCOF1 NOG NOG ENSMNEP00000030390 ENSMNEP00000030390 PEF1 PEF1 DDX5 DDX5 HGF HGF NOTCH4 NOTCH4 FGFR2 FGFR2 LOXL2 LOXL2 FLNA FLNA KBTBD8 KBTBD8 WNT11 WNT11 KLHL12 KLHL12 SOX9 SOX9 TGFB1 TGFB1 TGFB2 TGFB2 HIF1A HIF1A LEF1 LEF1 PPP3R1 PPP3R1 CUL7 CUL7 ROCK2 ROCK2 FGF8 FGF8 HNRNPAB HNRNPAB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HAS2Hyaluronan synthase 2. (552 aa)
NOTCH1Notch receptor 1. (2556 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
PDCD6Programmed cell death 6. (121 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
OLFM1Olfactomedin 1. (485 aa)
RFLNBRefilin B. (144 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MSX1Msh homeobox 1. (303 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (619 aa)
EOMESEomesodermin. (705 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
FAM83DFamily with sequence similarity 83 member D. (645 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ADAM15ADAM metallopeptidase domain 15. (861 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
RTN4Reticulon. (1118 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
EDN1Endothelin 1. (211 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
TMEM100Transmembrane protein 100. (134 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
FOXF2Forkhead box F2. (447 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
TBX3T-box transcription factor 3. (743 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (547 aa)
CTNNB1Catenin beta 1. (781 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (314 aa)
AKNAAT-hook transcription factor. (1437 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ENGEndoglin. (658 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
GSCGoosecoid homeobox. (259 aa)
TASORTranscription activation suppressor. (1612 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1158 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
TRIM28Tripartite motif containing 28. (835 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1524 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSMNEP00000030390BTB domain-containing protein. (492 aa)
PEF1Penta-EF-hand domain containing 1. (283 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (576 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
NOTCH4Notch receptor 4. (2001 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
FLNAFilamin A. (2647 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
KLHL12BTB domain-containing protein. (568 aa)
SOX9SRY-box transcription factor 9. (509 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
PPP3R1Uncharacterized protein. (189 aa)
CUL7Cullin 7; Belongs to the cullin family. (1780 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (332 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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