STRINGSTRING
ENSMNEP00000020493 ENSMNEP00000020493 TMOD1 TMOD1 POF1B POF1B ATRX ATRX FEM1B FEM1B GDF11 GDF11 ESR1 ESR1 TBC1D20 TBC1D20 CLIC4 CLIC4 SIDT2 SIDT2 IL6ST IL6ST NPHS1 NPHS1 EDNRA EDNRA GPR4 GPR4 MYO1E MYO1E RAB25 RAB25 RAPGEF2 RAPGEF2 EXPH5 EXPH5 RAPGEF3 RAPGEF3 MYADM MYADM EPAS1 EPAS1 PLEC PLEC RILPL2 RILPL2 ARID4B ARID4B RILPL1 RILPL1 LOC105464826 LOC105464826 PDE2A PDE2A EDNRB EDNRB VSIG1 VSIG1 ENSMNEP00000004514 ENSMNEP00000004514 ARHGEF26 ARHGEF26 WNT5A WNT5A BHLHA15 BHLHA15 FZD5 FZD5 E2F4 E2F4 SRC SRC SFN SFN DLL1 DLL1 TIGAR TIGAR ADAMTSL4 ADAMTSL4 ABI2 ABI2 PPP1R16B PPP1R16B NOTCH2 NOTCH2 DMD DMD PDE4D PDE4D RAB13 RAB13 KLF5 KLF5 FOSL2 FOSL2 TJP3 TJP3 GATA2 GATA2 RARA RARA AR AR C1GALT1 C1GALT1 HYDIN HYDIN RAPGEF1 RAPGEF1 TNMD TNMD NUP210L NUP210L NOTCH1 NOTCH1 AFDN AFDN AKR1B1 AKR1B1 TJP1 TJP1 ST14 ST14 ABCA12 ABCA12 IFT74 IFT74 WNT7B WNT7B RAP1A RAP1A ASXL1 ASXL1 IQGAP1 IQGAP1 PROX1 PROX1 EPB41L5 EPB41L5 TP63 TP63 RARG RARG PODXL PODXL FAT1 FAT1 COL18A1 COL18A1 BFSP2 BFSP2 YAP1 YAP1 PRDM1 PRDM1 COL15A1 COL15A1 GSTM3 GSTM3 ROS1 ROS1 MARVELD2 MARVELD2 STC1 STC1 LAMB2 LAMB2 SPDEF SPDEF DNASE1L2 DNASE1L2 NKX2-2 NKX2-2 PDPK1 PDPK1 CCM2 CCM2 BFSP1 BFSP1 BMP5 BMP5 FRMD6 FRMD6 RAP2C RAP2C FOXJ1 FOXJ1 HNF4A HNF4A SLC9A4 SLC9A4 CCDC88C CCDC88C GATA1 GATA1 NTRK1 NTRK1 KRT2 KRT2 SIX3 SIX3 CDH2 CDH2 HOXA13 HOXA13 HIF1A HIF1A EPHA2 EPHA2 KDR KDR TGFB1 TGFB1 ENSMNEP00000039571 ENSMNEP00000039571 ENSMNEP00000039545 ENSMNEP00000039545 IHH IHH KDF1 KDF1 PALLD PALLD RDX RDX COL22A1 COL22A1 RARB RARB HOXA5 HOXA5 MSN MSN SHROOM3 SHROOM3 B4GALT1 B4GALT1 RAP1B RAP1B CDK6 CDK6 TMEM79 TMEM79 MAGI2 MAGI2 NOTCH4 NOTCH4 SOX8 SOX8 ENSMNEP00000033108 ENSMNEP00000033108 BCL11B BCL11B MYD88 MYD88 YIPF6 YIPF6 TYMS TYMS EZR EZR DACT2 DACT2 ONECUT2 ONECUT2 GRHL2 GRHL2 MET MET FNDC3A FNDC3A HEG1 HEG1 RFX3 RFX3 PDGFB PDGFB JAG1 JAG1 FASN FASN CLDN3 CLDN3 ROCK1 ROCK1 HPSE HPSE FOXC2 FOXC2 VIM VIM VEZF1 VEZF1 ARID4A ARID4A ATF4 ATF4 NKX3-2 NKX3-2 PECAM1 PECAM1 FOXA1 FOXA1 PKHD1 PKHD1 SIPA1L3 SIPA1L3 SDC1 SDC1 PLOD3 PLOD3 FLNB FLNB BMP4 BMP4 HOXB13 HOXB13 HAPLN2 HAPLN2 ENSMNEP00000025369 ENSMNEP00000025369 FRZB FRZB DMRT1 DMRT1 FSHR FSHR NPHS2 NPHS2 PAX6 PAX6 FRS2 FRS2 FER FER CLDN1 CLDN1 BMP6 BMP6 F11R F11R PTPRS PTPRS BMP15 BMP15 ROBO4 ROBO4 SLC4A5 SLC4A5 HSD17B4 HSD17B4 SMO SMO SOX18 SOX18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000020493Uncharacterized protein. (88 aa)
TMOD1Tropomodulin 1. (359 aa)
POF1BPOF1B actin binding protein. (574 aa)
ATRXATRX chromatin remodeler. (2464 aa)
FEM1BFem-1 homolog B. (627 aa)
GDF11Growth differentiation factor 11. (459 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
TBC1D20TBC1 domain family member 20. (403 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SIDT2SID1 transmembrane family member 2. (858 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1217 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
RAB25RAB25, member RAS oncogene family. (196 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
EXPH5Exophilin 5. (2033 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (878 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
PLECPlectin. (4774 aa)
RILPL2Rab interacting lysosomal protein like 2. (167 aa)
ARID4BAT-rich interaction domain 4B. (1313 aa)
RILPL1Rab interacting lysosomal protein like 1. (417 aa)
LOC105464826Uncharacterized protein. (316 aa)
PDE2APhosphodiesterase. (942 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (516 aa)
VSIG1V-set and immunoglobulin domain containing 1. (423 aa)
ENSMNEP00000004514Aldo_ket_red domain-containing protein. (252 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
BHLHA15Basic helix-loop-helix family member a15. (191 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
E2F4E2F transcription factor 4. (415 aa)
SRCTyrosine-protein kinase. (644 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
ADAMTSL4ADAMTS like 4. (1100 aa)
ABI2Abl interactor 2. (513 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
NOTCH2Notch receptor 2. (2471 aa)
DMDDystrophin. (3685 aa)
PDE4DPhosphodiesterase. (809 aa)
RAB13Uncharacterized protein. (203 aa)
KLF5Kruppel like factor 5. (457 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (830 aa)
GATA2GATA binding protein 2. (480 aa)
RARARetinoic acid receptor alpha. (477 aa)
ARAndrogen receptor. (898 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (371 aa)
HYDINHYDIN axonemal central pair apparatus protein. (5115 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
TNMDTenomodulin. (317 aa)
NUP210LNucleoporin 210 like. (1831 aa)
NOTCH1Notch receptor 1. (2556 aa)
AFDNAfadin, adherens junction formation factor. (1836 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
TJP1Tight junction protein 1. (1743 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
IFT74Intraflagellar transport 74. (600 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ASXL1ASXL transcriptional regulator 1. (1536 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1627 aa)
PROX1Prospero homeobox 1. (737 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa)
RARGRetinoic acid receptor gamma. (456 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (522 aa)
FAT1FAT atypical cadherin 1. (4643 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1754 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
YAP1Yes associated protein 1. (506 aa)
PRDM1PR/SET domain 1. (825 aa)
COL15A1Uncharacterized protein. (1388 aa)
GSTM3Glutathione S-transferase. (225 aa)
ROS1Tyrosine-protein kinase receptor. (2338 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
STC1Stanniocalcin 1. (247 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
NKX2-2NK2 homeobox 2. (273 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (582 aa)
CCM2CCM2 scaffold protein. (466 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (659 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
FRMD6FERM domain containing 6. (622 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
FOXJ1Forkhead box J1. (421 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (800 aa)
CCDC88CCoiled-coil domain containing 88C. (2033 aa)
GATA1GATA binding protein 1. (413 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
KRT2Keratin 2; Belongs to the intermediate filament family. (641 aa)
SIX3SIX homeobox 3. (337 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
HOXA13Homeobox A13. (389 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
EPHA2EPH receptor A2. (976 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ENSMNEP00000039571Uncharacterized protein. (136 aa)
ENSMNEP00000039545Uncharacterized protein. (196 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
PALLDPalladin, cytoskeletal associated protein. (1124 aa)
RDXRadixin. (604 aa)
COL22A1Collagen type XXII alpha 1 chain. (1626 aa)
RARBRetinoic acid receptor beta. (448 aa)
HOXA5Homeobox A5. (270 aa)
MSNMoesin. (577 aa)
SHROOM3Shroom family member 3. (1996 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
RAP1BUncharacterized protein. (137 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TMEM79Transmembrane protein 79. (394 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
NOTCH4Notch receptor 4. (2001 aa)
SOX8SRY-box transcription factor 8. (361 aa)
ENSMNEP00000033108Uncharacterized protein. (217 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
YIPF6Protein YIPF. (236 aa)
TYMSThymidylate synthetase. (313 aa)
EZREzrin. (603 aa)
DACT2Dishevelled binding antagonist of beta catenin 2. (643 aa)
ONECUT2One cut domain family member. (429 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1403 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
HEG1Heart development protein with EGF like domains 1. (1346 aa)
RFX3Regulatory factor X3. (777 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
FASNFatty acid synthase. (2505 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
HPSEHeparanase. (545 aa)
FOXC2Forkhead box C2. (501 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
VEZF1Vascular endothelial zinc finger 1. (519 aa)
ARID4AAT-rich interaction domain 4A. (1262 aa)
ATF4Activating transcription factor 4. (351 aa)
NKX3-2NK3 homeobox 2. (333 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (717 aa)
FOXA1Forkhead box A1. (470 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4072 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1780 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (741 aa)
FLNBFilamin B. (2556 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
HOXB13Homeobox B13. (288 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (340 aa)
ENSMNEP00000025369Uncharacterized protein. (129 aa)
FRZBFrizzled related protein. (325 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
NPHS2NPHS2 stomatin family member, podocin. (380 aa)
PAX6Paired box 6. (462 aa)
FRS2Fibroblast growth factor receptor substrate 2. (515 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
F11RF11 receptor. (328 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1911 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
ROBO4Roundabout guidance receptor 4. (1007 aa)
SLC4A5Anion exchange protein. (1136 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (750 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (657 aa)
SOX18SRY-box transcription factor 18. (354 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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