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| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | ENSMNEP00000046151 | Helicase C-terminal domain-containing protein. (633 aa) |
| | CCL19 | C-C motif chemokine. (123 aa) |
| | CD1D | CD1d molecule. (337 aa) |
| | ENSMNEP00000045832 | Ig-like domain-containing protein. (319 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (582 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | LACC1 | Uncharacterized protein. (430 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) |
| | KLRD1 | Killer cell lectin like receptor D1. (179 aa) |
| | ENSMNEP00000043817 | Prohibitin. (263 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ENSMNEP00000043350 | Ig-like domain-containing protein. (233 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1340 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | NCR3 | Natural cytotoxicity triggering receptor 3. (176 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | DHX58 | DExH-box helicase 58. (678 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1035 aa) |
| | GATA1 | GATA binding protein 1. (413 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (507 aa) |
| | CD244 | CD244 molecule. (367 aa) |
| | FGR | Tyrosine-protein kinase. (529 aa) |
| | RABGEF1 | A20-type domain-containing protein. (469 aa) |
| | CADM1 | Cell adhesion molecule 1. (473 aa) |
| | ENSMNEP00000040882 | C-type lectin domain-containing protein. (239 aa) |
| | CD160 | CD160 molecule. (181 aa) |
| | SLAMF6 | SLAM family member 6. (331 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (540 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | BLK | Tyrosine-protein kinase. (505 aa) |
| | TNFRSF4 | TNF receptor superfamily member 4. (277 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | TYROBP | TYRO protein tyrosine kinase binding protein. (144 aa) |
| | MASP2 | Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | ENSMNEP00000037716 | Prohibitin. (236 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | EPHB2 | EPH receptor B2. (1063 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | C4A | Uncharacterized protein. (1744 aa) |
| | ENSMNEP00000037129 | Ig-like domain-containing protein. (346 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (416 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | IL23R | Interleukin 23 receptor. (576 aa) |
| | SHLD1 | Shieldin complex subunit 1. (205 aa) |
| | IL13RA2 | Interleukin 13 receptor subunit alpha 2. (388 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1833 aa) |
| | IL17A | Interleukin 17A. (155 aa) |
| | MALT1 | MALT1 paracaspase. (824 aa) |
| | ENSMNEP00000035659 | Prohibitin. (112 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | CD1C | CD1c molecule. (332 aa) |
| | MBL2 | Mannose binding lectin 2. (255 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (360 aa) |
| | CD300A | CD300a molecule. (296 aa) |
| | MZB1 | Marginal zone B and B1 cell specific protein. (188 aa) |
| | CD37 | Tetraspanin. (270 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | DHX36 | DEAH-box helicase 36. (1008 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (786 aa) |
| | CD84 | CD84 molecule. (345 aa) |
| | LTA | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa) |
| | HLA-F | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (440 aa) |
| | C17orf99 | Chromosome 17 open reading frame 99. (265 aa) |
| | TFRC | Transferrin receptor. (764 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | DENND1B | DENN domain containing 1B. (790 aa) |
| | ENSMNEP00000032223 | Prohibitin. (133 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | ARG1 | Arginase. (322 aa) |
| | TNFSF13 | TNF superfamily member 13; Belongs to the tumor necrosis factor family. (250 aa) |
| | C3 | Complement C3. (1642 aa) |
| | HPX | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | NECTIN2 | Nectin cell adhesion molecule 2. (513 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1926 aa) |
| | FCN2 | Ficolin 2. (337 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) |
| | FCN3 | Ficolin 3. (299 aa) |
| | IL17F | Interleukin 17F. (163 aa) |
| | KIR2DL4 | Uncharacterized protein. (416 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) |
| | SH2D1B | SH2 domain containing 1B. (132 aa) |
| | SNX4 | Sorting nexin 4. (416 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (519 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | SYK | Tyrosine-protein kinase. (629 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | LOC105477893 | Uncharacterized protein. (1747 aa) |
| | KLRK1 | Killer cell lectin like receptor K1. (216 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (365 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | HLX | H2.0 like homeobox. (495 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | ENSMNEP00000026182 | Prohibitin. (238 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) |
| | COLEC10 | Collectin subfamily member 10. (277 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | MR1 | Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (385 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | FOXP3 | Forkhead box P3. (456 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (719 aa) |
| | SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) |
| | SHLD2 | FAM35_C domain-containing protein. (801 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) |
| | ENSMNEP00000023924 | MHC_I-like_Ag-recog domain-containing protein. (162 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | FCER2 | Fc fragment of IgE receptor II. (321 aa) |
| | PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa) |
| | STXBP2 | Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (640 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | LOC105485223 | NTR domain-containing protein. (131 aa) |
| | ENSMNEP00000022134 | Helicase C-terminal domain-containing protein. (315 aa) |
| | MYO18A | Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2054 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (230 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | ENSMNEP00000021271 | Prohibitin. (286 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9. (222 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | SPON2 | Spondin 2. (331 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | ENSMNEP00000019919 | C-type lectin domain-containing protein. (191 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | CD1E | CD1e molecule. (387 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (846 aa) |
| | FOXF1 | Forkhead box F1. (380 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | COLEC11 | Collectin subfamily member 11. (280 aa) |
| | FCGR1A | Uncharacterized protein. (357 aa) |
| | FBXO38 | F-box protein 38. (1188 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | INAVA | Innate immunity activator. (703 aa) |
| | SCIMP | SLP adaptor and CSK interacting membrane protein. (126 aa) |
| | ENSMNEP00000018934 | MHC_I-like_Ag-recog domain-containing protein. (199 aa) |
| | KIR3DL3 | Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (316 aa) |
| | ENSMNEP00000018745 | Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (832 aa) |
| | ENSMNEP00000018092 | Prohibitin. (270 aa) |
| | CD226 | CD226 molecule. (316 aa) |
| | DDX21 | DExD-box helicase 21. (783 aa) |
| | STAT5B | Signal transducer and activator of transcription. (783 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1044 aa) |
| | ENSMNEP00000016907 | Prohibitin. (173 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | STX7 | Syntaxin 7; Belongs to the syntaxin family. (261 aa) |
| | DDX50 | Uncharacterized protein. (707 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2466 aa) |
| | MASP1 | Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (730 aa) |
| | ENSMNEP00000014571 | Prohibitin. (318 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | PVR | PVR cell adhesion molecule. (417 aa) |
| | STX4 | Syntaxin 4; Belongs to the syntaxin family. (297 aa) |
| | CLNK | Cytokine dependent hematopoietic cell linker. (443 aa) |
| | ITGB2 | Integrin beta. (921 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | ENSMNEP00000013138 | Ig-like domain-containing protein; Belongs to the MHC class I family. (352 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (535 aa) |
| | ENSMNEP00000012842 | Prohibitin. (239 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | DDX60 | DExD/H-box helicase 60. (1691 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) |
| | ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) |
| | GPRC5B | G protein-coupled receptor class C group 5 member B. (421 aa) |
| | ENSMNEP00000011919 | MHC_I-like_Ag-recog domain-containing protein. (259 aa) |
| | NFKBID | NFKB inhibitor delta. (469 aa) |
| | PHB | Prohibitin. (272 aa) |
| | SHB | SH2 domain containing adaptor protein B. (509 aa) |
| | PAXIP1 | PAX interacting protein 1. (1069 aa) |
| | RARA | Retinoic acid receptor alpha. (477 aa) |
| | C12orf4 | Chromosome 12 open reading frame 4. (552 aa) |
| | RTN4 | Reticulon. (1118 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | KLK5 | Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (291 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | DDX1 | DEAD-box helicase 1. (740 aa) |
| | ANKRD17 | Ankyrin repeat domain 17. (2603 aa) |
| | KMT5B | Lysine methyltransferase 5B. (885 aa) |
| | ENSMNEP00000008836 | FAM35_C domain-containing protein. (216 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (295 aa) |
| | LOC105474889 | AIG1-type G domain-containing protein. (307 aa) |
| | CD80 | CD80 molecule. (288 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | CD55 | CD55 molecule (Cromer blood group). (551 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | ENSMNEP00000007269 | VPS9 domain-containing protein. (363 aa) |
| | PGC | Progastricsin; Belongs to the peptidase A1 family. (388 aa) |
| | CD177 | CD177 molecule. (437 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (678 aa) |
| | UNC13D | Unc-13 homolog D. (1126 aa) |
| | LAG3 | Lymphocyte activating 3. (525 aa) |
| | ENSMNEP00000005266 | Prohibitin. (198 aa) |
| | FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CD1B | CD1b molecule. (333 aa) |
| | SEMA7A | Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (697 aa) |
| | ENSMNEP00000002536 | Prohibitin. (151 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | ARID5A | AT-rich interaction domain 5A. (594 aa) |
| | HLA-G | IGc1 domain-containing protein; Belongs to the MHC class I family. (354 aa) |
| | CD81 | Tetraspanin. (274 aa) |
| | TNFRSF14 | TNF receptor superfamily member 14. (280 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | LOC105467297 | Ig-like domain-containing protein; Belongs to the MHC class I family. (242 aa) |
| | KMT5C | Lysine methyltransferase 5C. (461 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) |
