node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOD1 | TNF | ENSMNEP00000034664 | ENSMNEP00000029202 | Aconitate decarboxylase 1. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.448 |
C3 | HPX | ENSMNEP00000031258 | ENSMNEP00000031248 | Complement C3. | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | 0.612 |
C3 | LOC105477893 | ENSMNEP00000031258 | ENSMNEP00000028254 | Complement C3. | Uncharacterized protein. | 0.566 |
CCR7 | IL1B | ENSMNEP00000012848 | ENSMNEP00000033521 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.573 |
CCR7 | LTA | ENSMNEP00000012848 | ENSMNEP00000032571 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.491 |
CCR7 | PTPRC | ENSMNEP00000012848 | ENSMNEP00000012745 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | Protein tyrosine phosphatase receptor type C. | 0.501 |
CCR7 | TNF | ENSMNEP00000012848 | ENSMNEP00000029202 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.696 |
HPX | C3 | ENSMNEP00000031248 | ENSMNEP00000031258 | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | Complement C3. | 0.612 |
HPX | LOC105477893 | ENSMNEP00000031248 | ENSMNEP00000028254 | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | Uncharacterized protein. | 0.565 |
IL17A | IL17F | ENSMNEP00000035713 | ENSMNEP00000030688 | Interleukin 17A. | Interleukin 17F. | 0.988 |
IL17A | IL1B | ENSMNEP00000035713 | ENSMNEP00000033521 | Interleukin 17A. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.703 |
IL17A | TNF | ENSMNEP00000035713 | ENSMNEP00000029202 | Interleukin 17A. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.667 |
IL17F | IL17A | ENSMNEP00000030688 | ENSMNEP00000035713 | Interleukin 17F. | Interleukin 17A. | 0.988 |
IL17F | IL1B | ENSMNEP00000030688 | ENSMNEP00000033521 | Interleukin 17F. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.556 |
IL17F | TNF | ENSMNEP00000030688 | ENSMNEP00000029202 | Interleukin 17F. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.526 |
IL1B | CCR7 | ENSMNEP00000033521 | ENSMNEP00000012848 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | 0.573 |
IL1B | IL17A | ENSMNEP00000033521 | ENSMNEP00000035713 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | Interleukin 17A. | 0.703 |
IL1B | IL17F | ENSMNEP00000033521 | ENSMNEP00000030688 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | Interleukin 17F. | 0.556 |
IL1B | LTA | ENSMNEP00000033521 | ENSMNEP00000032571 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.598 |
IL1B | NOD2 | ENSMNEP00000033521 | ENSMNEP00000017054 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | Nucleotide binding oligomerization domain containing 2. | 0.709 |