STRINGSTRING
MESP1 MESP1 NKX2-5 NKX2-5 SOX4 SOX4 WNT5A WNT5A NOTCH2 NOTCH2 NSD2 NSD2 NOTCH1 NOTCH1 GATA4 GATA4 PROX1 PROX1 BMPR2 BMPR2 TBX5 TBX5 SMO SMO ENG ENG WNT2 WNT2 SHOX2 SHOX2 BMP2 BMP2 ACVR1 ACVR1 HEY2 HEY2 NOG NOG HEG1 HEG1 DLL4 DLL4 ISL1 ISL1 ZFPM1 ZFPM1 BMP10 BMP10 TBX20 TBX20 TGFB2 TGFB2 SOS1 SOS1 CCN1 CCN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
NKX2-5NK2 homeobox 5. (324 aa)
SOX4Transcription factor SOX. (475 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
NOTCH2Notch receptor 2. (2471 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
NOTCH1Notch receptor 1. (2556 aa)
GATA4GATA binding protein 4. (443 aa)
PROX1Prospero homeobox 1. (737 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TBX5T-box transcription factor 5. (518 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (657 aa)
ENGEndoglin. (658 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SHOX2Short stature homeobox 2. (355 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HEG1Heart development protein with EGF like domains 1. (1346 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ZFPM1Zinc finger protein, FOG family member 1. (976 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
TBX20T-box transcription factor 20. (447 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
CCN1Cellular communication network factor 1. (381 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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