15 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	IL1A	Interleukin-1; Belongs to the IL-1 family. (224 aa)
	IL37	Interleukin-1. (235 aa)
	IL1RN	Interleukin-1. (179 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (460 aa)
	TRIP6	Thyroid hormone receptor interactor 6. (476 aa)
	IL36A	Interleukin-1. (179 aa)
	IL36RN	Interleukin-1. (155 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
	IL1F10	Interleukin-1. (152 aa)
	ERAP1	Aminopeptidase. (925 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (687 aa)
	TOLLIP	Toll interacting protein. (274 aa)
	IL36G	Interleukin-1. (169 aa)
	IL36B	Interleukin 36 beta. (164 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL1A	IL1B	ENSMNEP00000033931	ENSMNEP00000033521	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.998
IL1A	IL1F10	ENSMNEP00000033931	ENSMNEP00000028549	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.518
IL1A	IL1RAP	ENSMNEP00000033931	ENSMNEP00000026901	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.945
IL1A	IL1RN	ENSMNEP00000033931	ENSMNEP00000038614	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.675
IL1A	IL36A	ENSMNEP00000033931	ENSMNEP00000032471	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.518
IL1A	IL36B	ENSMNEP00000033931	ENSMNEP00000003446	Interleukin-1; Belongs to the IL-1 family.	Interleukin 36 beta.	0.507
IL1A	IL36G	ENSMNEP00000033931	ENSMNEP00000004810	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.556
IL1A	IL36RN	ENSMNEP00000033931	ENSMNEP00000032380	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.511
IL1A	IL37	ENSMNEP00000033931	ENSMNEP00000041053	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.535
IL1A	IRAK4	ENSMNEP00000033931	ENSMNEP00000033497	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor associated kinase 4.	0.698
IL1A	MYD88	ENSMNEP00000033931	ENSMNEP00000032156	Interleukin-1; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.756
IL1A	TOLLIP	ENSMNEP00000033931	ENSMNEP00000021574	Interleukin-1; Belongs to the IL-1 family.	Toll interacting protein.	0.523
IL1B	IL1A	ENSMNEP00000033521	ENSMNEP00000033931	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.998
IL1B	IL1F10	ENSMNEP00000033521	ENSMNEP00000028549	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.473
IL1B	IL1RAP	ENSMNEP00000033521	ENSMNEP00000026901	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.991
IL1B	IL1RN	ENSMNEP00000033521	ENSMNEP00000038614	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.702
IL1B	IL36A	ENSMNEP00000033521	ENSMNEP00000032471	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.530
IL1B	IL36B	ENSMNEP00000033521	ENSMNEP00000003446	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 36 beta.	0.463
IL1B	IL36G	ENSMNEP00000033521	ENSMNEP00000004810	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.514
IL1B	IL36RN	ENSMNEP00000033521	ENSMNEP00000032380	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.597