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| | ENSMNEP00000038473 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (214 aa) |
| | LOC105489051 | Uncharacterized protein. (113 aa) |
| | FIG4 | FIG4 phosphoinositide 5-phosphatase. (907 aa) |
| | OSBPL9 | Oxysterol-binding protein; Belongs to the OSBP family. (746 aa) |
| | HDAC6 | Histone deacetylase 6. (1183 aa) |
| | YIPF1 | Protein YIPF. (306 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (400 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (135 aa) |
| | SLC31A2 | Solute carrier family 31 member 2. (143 aa) |
| | SORL1 | Sortilin related receptor 1. (2184 aa) |
| | ENSMNEP00000044273 | Uncharacterized protein. (158 aa) |
| | KIDINS220 | Kinase D interacting substrate 220. (1771 aa) |
| | CDIP1 | Cell death inducing p53 target 1. (208 aa) |
| | LOC105474426 | Ig-like domain-containing protein. (263 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa) |
| | LAMP5 | Lysosomal associated membrane protein family member 5. (280 aa) |
| | MVB12B | Multivesicular body subunit 12B. (321 aa) |
| | ENSMNEP00000043369 | ABC transporter domain-containing protein. (194 aa) |
| | LOC105474413 | Ig-like domain-containing protein. (295 aa) |
| | SLC30A3 | Solute carrier family 30 member 3. (388 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | MITD1 | Microtubule interacting and trafficking domain containing 1. (274 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | LITAFD | LITAF domain containing. (72 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (949 aa) |
| | SLC9A6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa) |
| | ENSMNEP00000041440 | Uncharacterized protein. (168 aa) |
| | TPCN2 | Two pore segment channel 2. (752 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa) |
| | SLC11A1 | Solute carrier family 11 member 1. (477 aa) |
| | ENSMNEP00000040770 | Uncharacterized protein. (156 aa) |
| | ZP2 | Zona pellucida glycoprotein 2. (745 aa) |
| | CD79A | CD79a molecule. (225 aa) |
| | ENSMNEP00000040265 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (586 aa) |
| | ANXA2 | Annexin. (357 aa) |
| | ANKRD27 | Ankyrin repeat domain 27. (1040 aa) |
| | TF | Transferrin; Belongs to the transferrin family. (698 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (960 aa) |
| | TMEM9 | Transmembrane protein 9. (183 aa) |
| | NSG1 | Neuronal vesicle trafficking associated 1. (185 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (341 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (307 aa) |
| | ENSMNEP00000038764 | MENTAL domain-containing protein. (209 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | MDP1 | Magnesium dependent phosphatase 1. (164 aa) |
| | VAC14 | VAC14 component of PIKFYVE complex. (784 aa) |
| | AP5S1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | TSG101 | Tumor susceptibility 101. (390 aa) |
| | MCOLN3 | Mucolipin 3. (553 aa) |
| | CD300LG | CD300 molecule like family member g. (372 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (416 aa) |
| | MVB12A | Multivesicular body subunit 12A. (273 aa) |
| | CLTCL1 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1639 aa) |
| | SLC38A9 | Solute carrier family 38 member 9. (561 aa) |
| | MARCHF1 | Membrane associated ring-CH-type finger 1. (545 aa) |
| | MICALL2 | MICAL like 2. (904 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | ENSMNEP00000036052 | Uncharacterized protein. (331 aa) |
| | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa) |
| | DERL1 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa) |
| | ABCB6 | ATP binding cassette subfamily B member 6 (Langereis blood group). (856 aa) |
| | ENSMNEP00000035159 | Uncharacterized protein. (112 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (380 aa) |
| | RMC1 | Regulator of MON1-CCZ1. (657 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa) |
| | TMEM25 | Transmembrane protein 25. (457 aa) |
| | RAB27B | RAB27B, member RAS oncogene family. (218 aa) |
| | DERL2 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (265 aa) |
| | CLCN4 | Chloride channel protein. (760 aa) |
| | ATP10B | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1461 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | ENSMNEP00000033330 | Uncharacterized protein. (237 aa) |
| | GALNTL5 | Polypeptide N-acetylgalactosaminyltransferase like 5. (408 aa) |
| | LAMP3 | Lysosomal associated membrane protein 3. (418 aa) |
| | DYSF | Dysferlin. (2119 aa) |
| | ARL8A | ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | ENSMNEP00000032942 | UDENN domain-containing protein. (329 aa) |
| | LGMN | Legumain. (433 aa) |
| | SLC9A9 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (645 aa) |
| | VPS29 | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (214 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2522 aa) |
| | RUBCN | Rubicon autophagy regulator. (1011 aa) |
| | CRHBP | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | VPS26B | VPS26, retromer complex component B. (336 aa) |
| | ENSMNEP00000031290 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (579 aa) |
| | CD68 | CD68 molecule. (354 aa) |
| | TMEM192 | Transmembrane protein 192. (230 aa) |
| | VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa) |
| | ENSMNEP00000030339 | Uncharacterized protein. (459 aa) |
| | VPS37D | VPS37D subunit of ESCRT-I. (343 aa) |
| | ANKRD13B | Ankyrin repeat domain 13B. (626 aa) |
| | SLC39A14 | Solute carrier family 39 member 14. (427 aa) |
| | EXOC8 | Exocyst complex component 8. (725 aa) |
| | YIPF2 | Protein YIPF. (315 aa) |
| | ENSMNEP00000028818 | Uncharacterized protein. (212 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | LOC105476744 | Vac14_Fig4_bd domain-containing protein. (130 aa) |
| | ENSMNEP00000000089 | Uncharacterized protein. (197 aa) |
| | LDLR | Low density lipoprotein receptor. (783 aa) |
| | RAB9A | RAB9A, member RAS oncogene family. (201 aa) |
| | NPC1 | NPC intracellular cholesterol transporter 1. (1277 aa) |
| | AP5B1 | Adaptor related protein complex 5 subunit beta 1. (878 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1701 aa) |
| | CYB561A3 | Cytochrome b561 family member A3. (242 aa) |
| | RASGEF1B | RasGEF domain family member 1B. (521 aa) |
| | SIGLEC1 | Sialic acid binding Ig like lectin 1. (1709 aa) |
| | RAB27A | RAB27A, member RAS oncogene family. (221 aa) |
| | ENSMNEP00000002263 | Uncharacterized protein. (329 aa) |
| | TSPAN15 | Tetraspanin. (294 aa) |
| | SNX14 | Sorting nexin 14. (946 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (169 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | FYCO1 | FYVE and coiled-coil domain containing 1. (1497 aa) |
| | ABCA5 | ATP binding cassette subfamily A member 5. (1646 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | ENSMNEP00000002976 | Uncharacterized protein. (95 aa) |
| | SDF4 | Stromal cell derived factor 4. (407 aa) |
| | LRAT | Lecithin retinol acyltransferase. (230 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | LOC105486688 | Annexin. (363 aa) |
| | LOC105481479 | Uncharacterized protein. (115 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | LOC105497160 | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (444 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1306 aa) |
| | NDFIP2 | Nedd4 family interacting protein 2. (336 aa) |
| | UNC13D | Unc-13 homolog D. (1126 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa) |
| | GOSR2 | Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (213 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (218 aa) |
| | MCOLN1 | Mucolipin 1. (580 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | MMD | Monocyte to macrophage differentiation associated. (239 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | ENSMNEP00000006921 | Uncharacterized protein. (522 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | ENSMNEP00000007493 | Uncharacterized protein. (283 aa) |
| | SPAAR | Small regulatory polypeptide of amino acid response. (90 aa) |
| | RAB22A | RAB22A, member RAS oncogene family. (194 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (199 aa) |
| | BAIAP3 | BAI1 associated protein 3. (1191 aa) |
| | CLCN3 | Chloride channel protein. (853 aa) |
| | STOML1 | Stomatin like 1. (398 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | SNX16 | Sorting nexin 16. (344 aa) |
| | TMEM165 | GDT1 family protein. (326 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1184 aa) |
| | MREG | Melanoregulin. (214 aa) |
| | SLC30A4 | Solute carrier family 30 member 4. (429 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2512 aa) |
| | ARL8B | ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | SLC1A1 | Solute carrier family 1 member 1. (524 aa) |
| | RILP | Rab interacting lysosomal protein. (395 aa) |
| | PARM1 | Prostate androgen-regulated mucin-like protein 1. (317 aa) |
| | ENSMNEP00000011402 | Uncharacterized protein. (203 aa) |
| | LOC105498547 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (551 aa) |
| | NSG2 | Neuronal vesicle trafficking associated 2. (171 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | SFTPB | Surfactant protein B. (389 aa) |
| | ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1190 aa) |
| | AP5M1 | Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (490 aa) |
| | CST7 | Cystatin F. (145 aa) |
| | UBXN6 | UBX domain protein 6. (465 aa) |
| | TMEM106B | Transmembrane protein 106B. (274 aa) |
| | ATP7B | ATPase copper transporting beta. (1465 aa) |
| | LAPTM4A | Lysosomal protein transmembrane 4 alpha. (233 aa) |
| | VPS13C | Vacuolar protein sorting 13 homolog C. (3754 aa) |
| | GRN | Granulin precursor. (634 aa) |
| | ENSMNEP00000013103 | Uncharacterized protein. (90 aa) |
| | ENSMNEP00000013201 | C-type lectin domain-containing protein. (239 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | CCZ1 | Uncharacterized protein. (415 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | PLD3 | Phospholipase D family member 3. (490 aa) |
| | WASHC1 | WASH complex subunit 1. (473 aa) |
| | ECPAS | Ecm29 proteasome adaptor and scaffold. (1961 aa) |
| | ATP13A4 | ATPase 13A4; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1178 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | MCOLN2 | Mucolipin 2. (566 aa) |
| | TMEM59 | Transmembrane protein 59. (324 aa) |
| | STX7 | Syntaxin 7; Belongs to the syntaxin family. (261 aa) |
| | PMEL | Premelanosome protein. (703 aa) |
| | VPS33B | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (617 aa) |
| | STARD3 | StAR related lipid transfer domain containing 3. (493 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | ANKRD13A | Ankyrin repeat domain 13A. (584 aa) |
| | SPPL2A | Signal peptide peptidase like 2A. (480 aa) |
| | VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (519 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa) |
| | CD63 | Tetraspanin. (238 aa) |
| | ENSMNEP00000017179 | PA domain-containing protein. (156 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (210 aa) |
| | MARCHF8 | Membrane associated ring-CH-type finger 8. (573 aa) |
| | KIAA1324 | KIAA1324. (993 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa) |
| | STX8 | Syntaxin 8. (217 aa) |
| | SFTPA1 | C-type lectin domain-containing protein. (248 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | WDR91 | WD repeat domain 91. (747 aa) |
| | CLCN6 | Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (903 aa) |
| | ENSMNEP00000019155 | Interfer-bind domain-containing protein. (338 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1055 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | SFTPD | Surfactant protein D. (375 aa) |
| | VPS18 | VPS18 core subunit of CORVET and HOPS complexes. (973 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (125 aa) |
| | VPS37A | VPS37A subunit of ESCRT-I. (397 aa) |
| | AP1AR | Adaptor related protein complex 1 associated regulatory protein. (302 aa) |
| | ENSMNEP00000019591 | Uncharacterized protein. (83 aa) |
| | CD1E | CD1e molecule. (387 aa) |
| | SCARB2 | Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa) |
| | WDR48 | WD repeat domain 48. (714 aa) |
| | IGF2R | Insulin like growth factor 2 receptor. (2491 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (886 aa) |
| | LOC105494194 | Uncharacterized protein. (222 aa) |
| | LOC105465405 | Charged multivesicular body protein 3. (222 aa) |
| | LITAF | Lipopolysaccharide induced TNF factor. (161 aa) |
| | OSBPL11 | Oxysterol-binding protein; Belongs to the OSBP family. (752 aa) |
| | ENSMNEP00000020540 | Uncharacterized protein. (299 aa) |
| | SLC30A2 | Solute carrier family 30 member 2. (372 aa) |
| | ENSMNEP00000020734 | Uncharacterized protein. (74 aa) |
| | STARD3NL | MENTAL domain-containing protein. (234 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (196 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (411 aa) |
| | VPS4B | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (532 aa) |
| | RNF128 | Ring finger protein 128. (428 aa) |
| | NEDD4L | NEDD4 like E3 ubiquitin protein ligase. (1259 aa) |
| | AP5Z1 | Adaptor related protein complex 5 subunit zeta 1. (811 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | VPS37C | VPS37C subunit of ESCRT-I. (355 aa) |
| | SLC17A8 | Solute carrier family 17 member 8. (589 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (498 aa) |
| | ENSMNEP00000022820 | Uncharacterized protein. (148 aa) |
| | ANKRD13D | Ankyrin repeat domain 13D. (605 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (559 aa) |
| | MON1A | MON1 homolog A, secretory trafficking associated. (652 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | TMEM230 | Uncharacterized protein. (177 aa) |
| | ENSMNEP00000023823 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (520 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa) |
| | ANXA6 | Annexin. (649 aa) |
| | SMIM22 | Small integral membrane protein 22. (138 aa) |
| | ENSMNEP00000025146 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (572 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (811 aa) |
| | UVRAG | UV radiation resistance associated. (699 aa) |
| | MR1 | Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (385 aa) |
| | VAMP5 | Vesicle associated membrane protein 5. (116 aa) |
| | ENSMNEP00000025490 | V-SNARE domain-containing protein. (198 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | BST2 | Bone marrow stromal cell antigen 2. (182 aa) |
| | TTPA | Alpha tocopherol transfer protein. (278 aa) |
| | DENND10 | UDENN domain-containing protein. (352 aa) |
| | SLA2 | Src like adaptor 2. (261 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | SLC29A3 | Solute carrier family 29 member 3. (475 aa) |
| | MFSD12 | Major facilitator superfamily domain containing 12. (511 aa) |
| | WDR81 | WD repeat domain 81. (1928 aa) |
| | STEAP3 | STEAP3 metalloreductase. (498 aa) |
| | VPS37B | VPS37B subunit of ESCRT-I. (285 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1698 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | CLN3 | Battenin. (438 aa) |
| | LAMTOR4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (112 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (223 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | HTT | Huntingtin. (3123 aa) |
| | MON1B | MON1 homolog B, secretory trafficking associated. (547 aa) |
| | NAPSA | Napsin A aspartic peptidase; Belongs to the peptidase A1 family. (421 aa) |
| | SLC11A2 | Solute carrier family 11 member 2. (568 aa) |
