STRINGSTRING
LOC105470579 LOC105470579 PACS1 PACS1 CLBA1 CLBA1 SLC18A3 SLC18A3 ATP7A ATP7A STK26 STK26 MAP6D1 MAP6D1 CLTC CLTC DIPK2A DIPK2A CLHC1 CLHC1 SYNRG SYNRG TMED10 TMED10 COPA COPA PRR15L PRR15L AP1S2 AP1S2 ZDHHC17 ZDHHC17 MAP6 MAP6 STEAP2 STEAP2 CHIC2 CHIC2 RAB13 RAB13 NCALD NCALD ENSMNEP00000010193 ENSMNEP00000010193 LRRK2 LRRK2 ACR ACR KDELR3 KDELR3 ENSMNEP00000012395 ENSMNEP00000012395 KDELR1 KDELR1 TMED7 TMED7 CNGA4 CNGA4 SPPL3 SPPL3 COPE COPE SPPL2A SPPL2A AP1G2 AP1G2 PI4KA PI4KA AP1B1 AP1B1 COPG1 COPG1 VPS41 VPS41 SCYL1 SCYL1 CLRN1 CLRN1 NRGN NRGN RASSF9 RASSF9 RAB8B RAB8B IGF2R IGF2R TGOLN2 TGOLN2 SORT1 SORT1 AP1S1 AP1S1 FURIN FURIN COPG2 COPG2 TMEM199 TMEM199 AP1G1 AP1G1 SLC2A4 SLC2A4 SCFD1 SCFD1 CNGA2 CNGA2 ITM2B ITM2B ZDHHC13 ZDHHC13 CSPG5 CSPG5 AP2A1 AP2A1 COPZ2 COPZ2 RHOQ RHOQ COPB2 COPB2 COPZ1 COPZ1 OCRL OCRL TMED2 TMED2 PACSIN1 PACSIN1 SPPL2B SPPL2B CLTB CLTB RAB27B RAB27B CNGB1 CNGB1 SPG21 SPG21 AFTPH AFTPH CLTA CLTA ADAM10 ADAM10 COPB1 COPB1 GOPC GOPC CLTCL1 CLTCL1 AP1S3 AP1S3 CCDC115 CCDC115 AP1M2 AP1M2 ENSMNEP00000039545 ENSMNEP00000039545 PKD1 PKD1 ARCN1 ARCN1 BACE1 BACE1 TSGA13 TSGA13 STK16 STK16 TMED9 TMED9 KDELR2 KDELR2 TTC17 TTC17 TMED3 TMED3 APP APP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105470579Uncharacterized protein. (245 aa)
PACS1Phosphofurin acidic cluster sorting protein 1. (1089 aa)
CLBA1Clathrin binding box of aftiphilin containing 1. (325 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
STK26Serine/threonine kinase 26. (428 aa)
MAP6D1MAP6 domain containing 1. (203 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
SYNRGSynergin gamma. (1415 aa)
TMED10Transmembrane p24 trafficking protein 10. (219 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1233 aa)
PRR15LProline rich 15 like. (103 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa)
MAP6Microtubule associated protein 6. (792 aa)
STEAP2STEAP2 metalloreductase. (490 aa)
CHIC2Cysteine rich hydrophobic domain 2. (165 aa)
RAB13Uncharacterized protein. (203 aa)
NCALDNeurocalcin delta. (193 aa)
ENSMNEP00000010193GOLD domain-containing protein; Belongs to the EMP24/GP25L family. (190 aa)
LRRK2Leucine rich repeat kinase 2. (2512 aa)
ACRAcrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. (399 aa)
KDELR3ER lumen protein-retaining receptor. (214 aa)
ENSMNEP00000012395GOLD domain-containing protein. (188 aa)
KDELR1KDEL endoplasmic reticulum protein retention receptor 1. (220 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
COPECoatomer protein complex subunit epsilon. (340 aa)
SPPL2ASignal peptide peptidase like 2A. (480 aa)
AP1G2AP-1 complex subunit gamma. (785 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2118 aa)
AP1B1AP complex subunit beta. (949 aa)
COPG1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (928 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
SCYL1SCY1 like pseudokinase 1. (808 aa)
CLRN1Clarin 1. (245 aa)
NRGNNeurogranin. (78 aa)
RASSF9Ras association domain family member 9. (452 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
IGF2RInsulin like growth factor 2 receptor. (2491 aa)
TGOLN2Trans-golgi network protein 2. (417 aa)
SORT1Sortilin. (831 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
COPG2Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa)
TMEM199Transmembrane protein 199. (208 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (559 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
ITM2BIntegral membrane protein 2B. (266 aa)
ZDHHC13Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (622 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (556 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (210 aa)
RHOQRas homolog family member Q. (193 aa)
COPB2Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (906 aa)
COPZ1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (197 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (900 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
SPPL2BSignal peptide peptidase like 2B. (546 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (1247 aa)
SPG21SPG21 abhydrolase domain containing, maspardin. (308 aa)
AFTPHAftiphilin. (935 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
COPB1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
GOPCPDZ domain-containing protein. (462 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1639 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
CCDC115Coiled-coil domain containing 115. (209 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (400 aa)
ENSMNEP00000039545Uncharacterized protein. (196 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (544 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
TSGA13Testis specific 13. (275 aa)
STK16Serine/threonine kinase 16. (349 aa)
TMED9Transmembrane p24 trafficking protein 9. (235 aa)
KDELR2ER lumen protein-retaining receptor. (323 aa)
TTC17Tetratricopeptide repeat domain 17. (1198 aa)
TMED3Transmembrane p24 trafficking protein 3. (246 aa)
APPAmyloid beta precursor protein. (770 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.