node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAD | CPS1 | ENSMNEP00000014237 | ENSMNEP00000023976 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Carbamoyl-phosphate synthase 1. | 0.995 |
CAD | CTPS1 | ENSMNEP00000014237 | ENSMNEP00000042641 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.545 |
CAD | CTPS2 | ENSMNEP00000014237 | ENSMNEP00000027325 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.513 |
CAD | DHODH | ENSMNEP00000014237 | ENSMNEP00000001649 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.999 |
CAD | DPYD | ENSMNEP00000014237 | ENSMNEP00000009049 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.945 |
CAD | DPYS | ENSMNEP00000014237 | ENSMNEP00000018180 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydropyrimidinase. | 0.830 |
CAD | ENSMNEP00000023472 | ENSMNEP00000014237 | ENSMNEP00000023472 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.917 |
CAD | UMPS | ENSMNEP00000014237 | ENSMNEP00000026701 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine monophosphate synthetase. | 0.917 |
CDA | CMPK1 | ENSMNEP00000022025 | ENSMNEP00000027464 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.486 |
CDA | CTPS1 | ENSMNEP00000022025 | ENSMNEP00000042641 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.423 |
CDA | CTPS2 | ENSMNEP00000022025 | ENSMNEP00000027325 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.423 |
CDA | DHODH | ENSMNEP00000022025 | ENSMNEP00000001649 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.655 |
CDA | DPYD | ENSMNEP00000022025 | ENSMNEP00000009049 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.639 |
CDA | ENSMNEP00000023472 | ENSMNEP00000022025 | ENSMNEP00000023472 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uncharacterized protein. | 0.491 |
CDA | TYMP | ENSMNEP00000022025 | ENSMNEP00000044984 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.999 |
CDA | TYMS | ENSMNEP00000022025 | ENSMNEP00000031849 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidylate synthetase. | 0.887 |
CDA | UMPS | ENSMNEP00000022025 | ENSMNEP00000026701 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine monophosphate synthetase. | 0.491 |
CMPK1 | CDA | ENSMNEP00000027464 | ENSMNEP00000022025 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.486 |
CMPK1 | CTPS1 | ENSMNEP00000027464 | ENSMNEP00000042641 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.533 |
CMPK1 | CTPS2 | ENSMNEP00000027464 | ENSMNEP00000027325 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.533 |